Cas no 1804381-07-4 (4-Bromo-6-fluoropicolinonitrile)
4-Bromo-6-fluoropicolinonitrile is a halogenated pyridine derivative with significant utility in pharmaceutical and agrochemical synthesis. The presence of both bromo and fluoro substituents on the pyridine ring enhances its reactivity, making it a versatile intermediate for cross-coupling reactions, nucleophilic substitutions, and other functionalization processes. The nitrile group further expands its applicability in heterocyclic chemistry, enabling transformations into amides, carboxylic acids, or tetrazoles. This compound is particularly valuable in the development of bioactive molecules due to its ability to introduce structural diversity. High purity and stability under standard conditions ensure reliable performance in synthetic applications.
1804381-07-4 structure
Product Name:4-Bromo-6-fluoropicolinonitrile
CAS No:1804381-07-4
MF:C6H2BrFN2
MW:200.995883464813
CID:4900394
Update Time:2025-10-17
4-Bromo-6-fluoropicolinonitrile Chemical and Physical Properties
Names and Identifiers
-
- 4-bromo-6-fluoropicolinonitrile
- 4-Bromo-6-fluoropicolinonitrile
-
- Inchi: 1S/C6H2BrFN2/c7-4-1-5(3-9)10-6(8)2-4/h1-2H
- InChI Key: NSCIYWIBWLYYLK-UHFFFAOYSA-N
- SMILES: BrC1C=C(N=C(C#N)C=1)F
Computed Properties
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 10
- Rotatable Bond Count: 0
- Complexity: 164
- XLogP3: 2
- Topological Polar Surface Area: 36.7
4-Bromo-6-fluoropicolinonitrile Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A029013722-250mg |
4-Bromo-6-fluoropicolinonitrile |
1804381-07-4 | 95% | 250mg |
$1,048.60 | 2022-04-02 | |
| Alichem | A029013722-1g |
4-Bromo-6-fluoropicolinonitrile |
1804381-07-4 | 95% | 1g |
$3,010.80 | 2022-04-02 |
4-Bromo-6-fluoropicolinonitrile Related Literature
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Piotr Szcze?niak,Sebastian Stecko RSC Adv., 2015,5, 30882-30888
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Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099
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H. V. Jain,D. Verthelyi,S. L. Beaucage RSC Adv., 2017,7, 42519-42528
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4. An integrated microfluidic 3D tumor system for parallel and high-throughput chemotherapy evaluation?Dan Liu,Rui Hu,Zhongchao Huang,Meilin Sun,Kai Han Analyst, 2020,145, 6447-6455
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Yaqing Liu,Jiangtao Ren,Jing Li,Jiyang Liu,Erkang Wang Chem. Commun., 2012,48, 802-804
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