Cas no 1785371-84-7 ((2-(Difluoromethyl)thiazol-4-yl)methanamine)
(2-(Difluoromethyl)thiazol-4-yl)methanamine is a versatile heterocyclic amine derivative featuring a difluoromethyl-substituted thiazole core. Its unique structure, combining a thiazole ring with a difluoromethyl group and a primary amine functionality, makes it a valuable intermediate in pharmaceutical and agrochemical synthesis. The difluoromethyl moiety enhances metabolic stability and bioavailability, while the amine group provides a reactive site for further derivatization. This compound is particularly useful in the development of bioactive molecules, including enzyme inhibitors and receptor modulators. Its well-defined reactivity and stability under standard conditions ensure consistent performance in synthetic applications. High purity and precise characterization further support its utility in research and industrial settings.
1785371-84-7 structure
Product Name:(2-(Difluoromethyl)thiazol-4-yl)methanamine
CAS No:1785371-84-7
MF:C5H6F2N2S
MW:164.176346302032
CID:6343710
PubChem ID:84764771
Update Time:2025-10-19
(2-(Difluoromethyl)thiazol-4-yl)methanamine Chemical and Physical Properties
Names and Identifiers
-
- (2-(Difluoromethyl)thiazol-4-yl)methanamine
- [2-(difluoromethyl)-1,3-thiazol-4-yl]methanamine
- 1785371-84-7
- EN300-7056754
-
- Inchi: 1S/C5H6F2N2S/c6-4(7)5-9-3(1-8)2-10-5/h2,4H,1,8H2
- InChI Key: RKHHUFQXXRGEQQ-UHFFFAOYSA-N
- SMILES: S1C=C(CN)N=C1C(F)F
Computed Properties
- Exact Mass: 164.02197570g/mol
- Monoisotopic Mass: 164.02197570g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 10
- Rotatable Bond Count: 2
- Complexity: 112
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 0.5
- Topological Polar Surface Area: 67.2?2
(2-(Difluoromethyl)thiazol-4-yl)methanamine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Enamine | EN300-7056754-0.05g |
[2-(difluoromethyl)-1,3-thiazol-4-yl]methanamine |
1785371-84-7 | 95.0% | 0.05g |
$912.0 | 2025-03-12 | |
| Enamine | EN300-7056754-0.1g |
[2-(difluoromethyl)-1,3-thiazol-4-yl]methanamine |
1785371-84-7 | 95.0% | 0.1g |
$956.0 | 2025-03-12 | |
| Enamine | EN300-7056754-0.25g |
[2-(difluoromethyl)-1,3-thiazol-4-yl]methanamine |
1785371-84-7 | 95.0% | 0.25g |
$999.0 | 2025-03-12 | |
| Enamine | EN300-7056754-0.5g |
[2-(difluoromethyl)-1,3-thiazol-4-yl]methanamine |
1785371-84-7 | 95.0% | 0.5g |
$1043.0 | 2025-03-12 | |
| Enamine | EN300-7056754-1.0g |
[2-(difluoromethyl)-1,3-thiazol-4-yl]methanamine |
1785371-84-7 | 95.0% | 1.0g |
$1086.0 | 2025-03-12 | |
| Enamine | EN300-7056754-2.5g |
[2-(difluoromethyl)-1,3-thiazol-4-yl]methanamine |
1785371-84-7 | 95.0% | 2.5g |
$2127.0 | 2025-03-12 | |
| Enamine | EN300-7056754-5.0g |
[2-(difluoromethyl)-1,3-thiazol-4-yl]methanamine |
1785371-84-7 | 95.0% | 5.0g |
$3147.0 | 2025-03-12 | |
| Enamine | EN300-7056754-10.0g |
[2-(difluoromethyl)-1,3-thiazol-4-yl]methanamine |
1785371-84-7 | 95.0% | 10.0g |
$4667.0 | 2025-03-12 |
(2-(Difluoromethyl)thiazol-4-yl)methanamine Related Literature
-
Li-Hua Gan,Rui Wu,Jian-Lei Tian,Patrick W. Fowler Phys. Chem. Chem. Phys., 2017,19, 419-425
-
Kanjun Sun,Fengting Hua,Shuzhen Cui,Yanrong Zhu,Hui Peng,Guofu Ma RSC Adv., 2021,11, 37631-37642
-
Supaporn Sawadjoon,Joseph S. M. Samec Org. Biomol. Chem., 2011,9, 2548-2554
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Yu-Nong Li,Liang-Nian He,Xian-Dong Lang,Xiao-Fang Liu,Shuai Zhang RSC Adv., 2014,4, 49995-50002
-
Yang Xu,Min Wang,Donghui Wei,Rongqiang Tian,Zheng Duan,Fran?ois Mathey Dalton Trans., 2019,48, 5523-5526
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