Cas no 17833-53-3 (N-Methyl-DL-aspartic acid)

N-Methyl-DL-aspartic acid is a synthetic derivative of aspartic acid, featuring a methyl group substitution at the nitrogen atom. This modification enhances its utility in biochemical and pharmacological research, particularly as an excitatory amino acid receptor agonist. It is commonly employed in studies of neurotransmission, synaptic plasticity, and neurotoxicity due to its ability to selectively activate NMDA and metabotropic glutamate receptors. The racemic (DL) form allows for broad experimental applications, including investigations into receptor binding and neuronal signaling pathways. Its stability and solubility in aqueous solutions make it suitable for in vitro and in vivo studies. The compound is widely used in neuroscience research to explore mechanisms underlying neurological disorders.
N-Methyl-DL-aspartic acid structure
N-Methyl-DL-aspartic acid structure
Product Name:N-Methyl-DL-aspartic acid
CAS No:17833-53-3
MF:C5H9NO4
MW:147.129261732101
MDL:MFCD00065918
CID:144131
Update Time:2025-10-24

N-Methyl-DL-aspartic acid Chemical and Physical Properties

Names and Identifiers

    • N-Methyl-DL-aspartic acid
    • Aspartic acid,N-methyl-
    • N-Me-DL-Asp-OH
    • Aspartic acid,N-methyl
    • DL-2-METHYLAMINOSUCCINIC ACID
    • DL-Aspartic acid,N-methyl
    • L-Aspartic acid,N-methyl
    • N-methylaminosuccinic acid
    • N-methylaspartic acid
    • N-methyl-D,L-aspartate
    • Asparticacid, N-methyl-, DL- (8CI)
    • DL-Aspartic acid, N-methyl-
    • DL-N-Methylasparticacid
    • NMDA
    • N-Methyl-DL-aspartate
    • 2-(Methylamino)succinic acid
    • 2-(methylamino)butanedioic acid
    • L-Aspartic acid, N-methyl-
    • H-D-MeAsp-OH
    • 2-Methylaminosuccinic acid
    • KSC492K7T
    • HMS3652P20
    • HMS3675A03
    • HMS3411A03
    • HMS3370L14
    • HMS3266A05
    • NSC16206
    • BCP21209
    • STK246904
    • FCH831963
    • BDBM50002343
    • MCUL
    • MDL: MFCD00065918
    • Inchi: 1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)
    • InChI Key: HOKKHZGPKSLGJE-UHFFFAOYSA-N
    • SMILES: OC(C(CC(=O)O)NC)=O

Computed Properties

  • Exact Mass: 147.05300
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 4
  • Complexity: 145
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: -3.4
  • Topological Polar Surface Area: 86.6

Experimental Properties

  • Solubility: H2O: 25?mg/mL, clear, colorless
  • PSA: 86.63000
  • LogP: -0.47540

N-Methyl-DL-aspartic acid Security Information

  • WGK Germany:3
  • Safety Instruction: S22; S24/25
  • FLUKA BRAND F CODES:10

N-Methyl-DL-aspartic acid Customs Data

  • HS CODE:2922499990
  • Customs Data:

    China Customs Code:

    2922499990

    Overview:

    2922499990 Other amino acids and their esters and their salts(Except those containing more than one oxygen-containing group). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods) MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, The color of ethanolamine and its salt should be reported, The package of ethanolamine and its salt shall be declared

    Regulatory conditions:

    A.Customs clearance form for Inbound Goods
    B.Customs clearance form for outbound goods

    Inspection and quarantine category:

    P.Imported animals and plants\Quarantine of animal and plant products
    Q.Outbound animals and plants\Quarantine of animal and plant products
    R.Sanitary supervision and inspection of imported food
    S.Sanitary supervision and inspection of exported food
    M.Import commodity inspection
    N.Export commodity inspection

    Summary:

    HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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N-Methyl-DL-aspartic acid Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:17833-53-3)N-Methyl-DL-aspartic acid
Order Number:A881399
Stock Status:in Stock
Quantity:500g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 11:03
Price ($):290.0
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:17833-53-3)甲基天冬氨酸
Order Number:LE27068913
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 13:04
Price ($):discuss personally

Additional information on N-Methyl-DL-aspartic acid

N-Methyl-DL-Aspartic Acid: A Comprehensive Overview

N-Methyl-DL-Aspartic Acid, commonly referred to as NMA and identified by the CAS Number 17833-53-3, is a significant compound in the field of chemistry and biochemistry. This compound, also known as DL-N-methylaspartate, has garnered attention due to its versatile applications across various industries, including food additives, pharmaceuticals, and nutraceuticals. Recent advancements in research have further highlighted its potential in areas such as neuroscience and material science.

The chemical structure of N-Methyl-DL-Aspartic Acid consists of a methyl group attached to the nitrogen atom of the aspartic acid molecule. This modification imparts unique properties to the compound, making it more stable and bioavailable compared to its unmodified counterpart. The compound is synthesized through a series of chemical reactions, including methylation of aspartic acid, which is typically derived from renewable resources or synthetic processes.

One of the most notable applications of N-Methyl-DL-Aspartic Acid is in the food industry, where it serves as a flavor enhancer. Its ability to enhance umami flavors makes it a valuable ingredient in soups, sauces, and processed foods. Recent studies have explored its synergistic effects with other flavor compounds, leading to innovative formulations that cater to evolving consumer preferences for natural and healthy food products.

In the pharmaceutical sector, N-Methyl-DL-Aspartic Acid has been investigated for its potential therapeutic benefits. Research indicates that it may play a role in neuroprotection by modulating glutamate receptors, which are critical in neuronal communication. This property has led to exploratory studies in treating neurodegenerative diseases such as Alzheimer's and Parkinson's. Additionally, its role in amino acid metabolism has been studied in the context of sports nutrition, where it is believed to enhance physical performance and recovery.

The compound's stability under various pH conditions and thermal treatments makes it suitable for use in processed foods and beverages. Recent advancements in food chemistry have focused on optimizing its delivery systems to ensure maximum efficacy while maintaining sensory quality. For instance, encapsulation techniques have been developed to protect the compound from degradation during processing and storage.

From an environmental perspective, the production and use of N-Methyl-DL-Aspartic Acid are increasingly aligned with sustainable practices. Researchers are exploring green chemistry methods for its synthesis, including enzymatic catalysis and fermentation processes that reduce reliance on petrochemical feedstocks. These efforts aim to minimize the environmental footprint while maintaining high-quality standards.

In conclusion, N-Methyl-DL-Aspartic Acid (CAS No. 17833-53-3) is a multifaceted compound with applications spanning various industries. Its unique chemical properties, coupled with ongoing research into its biological effects and sustainable production methods, position it as a key ingredient in modern formulations. As scientific understanding deepens, so too does its potential for innovation across diverse fields.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:17833-53-3)N-Methyl-DL-aspartic acid
A881399
Purity:99%
Quantity:500g
Price ($):290.0
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:17833-53-3)甲基天冬氨酸
LE27068913
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
Email