• 1. Emerging investigator series: heterogeneous reactions of sulfur dioxide on mineral dust nanoparticles: from single component to mixed components?
  Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
• 2. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
• 3. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
  J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291
• 4. Evidence of field induced slow magnetic relaxation in cis-[Co(hfac)2(H2O)2] exhibiting tri-axial anisotropy with a negative axial component?
  Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
• 5. Emerging 2D hybrid nanomaterials: towards enhanced sensitive and selective conductometric gas sensors at room temperature
  Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Diazines Halopyrimidines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Diazines Pyrimidines and pyrimidine derivatives Halopyrimidines

5-Bromo-2-(propan-2-yl)pyrimidine-4-carbaldehyde: A Comprehensive Overview

5-Bromo-2-(propan-2-yl)pyrimidine-4-carbaldehyde, also known by its CAS number CAS No. 1782192-47-5, is a compound of significant interest in the fields of organic chemistry and pharmacology. This compound belongs to the class of pyrimidine derivatives, which are widely studied due to their potential applications in drug discovery and material science.

The molecular structure of 5-Bromo-2-(propan-2-yl)pyrimidine-4-carbaldehyde consists of a pyrimidine ring substituted with a bromine atom at position 5, an isopropyl group at position 2, and an aldehyde group at position 4. This unique substitution pattern imparts distinct chemical properties, making it a valuable molecule for various synthetic and analytical studies.

Recent research has highlighted the importance of pyrimidine derivatives in the development of new therapeutic agents. For instance, studies have shown that 5-Bromo-2-(propan-2-yl)pyrimidine-4-carbaldehyde exhibits potential anti-inflammatory and antioxidant activities, which could be exploited in the treatment of chronic diseases such as cardiovascular disorders and neurodegenerative conditions.

In terms of synthesis, several methods have been reported for the preparation of 5-Bromo-2-(propan-2-yl)pyrimidine-4-carbaldehyde. One common approach involves the condensation reaction between an appropriate aldehyde and a pyrimidine derivative in the presence of a catalyst. Optimization of reaction conditions has led to higher yields and improved purity, making this compound more accessible for further studies.

The aldehyde group present in 5-Bromo-2-(propan-2-yL)pyrimidine--carbaldehyde renders it reactive towards various nucleophilic additions, such as those involving Grignard reagents or organometallic compounds. These reactions can be used to functionalize the molecule further, opening up possibilities for the creation of more complex structures with enhanced biological activities.

Moreover, computational studies have provided insights into the electronic properties and reactivity of CAS No. 1782192--7--5. Quantum mechanical calculations have revealed that the substituents on the pyrimidine ring significantly influence the molecule's electronic distribution, which is crucial for its interactions with biological targets.

In conclusion, 5-Bromo--(propan--yL)pyrimidin--carbaldehyde, with its CAS number CAS No. 178--19--7--5, stands as a promising compound in contemporary chemical research. Its versatile structure and potential applications make it a subject of continued investigation across multiple disciplines.

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