Cas no 17466-45-4 (Phalloidin)
Phalloidin is a bicyclic heptapeptide toxin derived from the death cap mushroom (Amanita phalloides). It is widely utilized in life sciences research due to its high affinity for F-actin, stabilizing filamentous actin structures and preventing depolymerization. This property makes it a valuable tool for visualizing actin cytoskeletons in fluorescence microscopy, often conjugated to fluorophores such as FITC, TRITC, or Alexa Fluor dyes. Phalloidin's selective binding enables precise localization of actin filaments in fixed cells, aiding studies in cell motility, morphology, and structural organization. Its stability and specificity ensure minimal interference with cellular architecture, providing reliable results in cytoskeletal research.
Phalloidin structure
Product Name:Phalloidin
CAS No:17466-45-4
MF:C35H48N8O11S
MW:788.86762714386
MDL:MFCD06201852
CID:194943
PubChem ID:24898277
Update Time:2025-10-19
Phalloidin Chemical and Physical Properties
Names and Identifiers
-
- Phalloidin
- Phalloidin from Amanita phalloides
- Phalloidin, Amanita phalloides
- 28-(2,3-dihydroxy-2-methylpropyl)-18-hydroxy-34-(1-hydroxyethyl)-23,31-dimethyl-12-thia-10,16,22,25,27,30,33,36-octaazapentacyclo[12.11.11.03,11.04,9.016,20]hexatriaconta-3(11),4,6,8-tetraene-15,21,24,26,29,32,35-heptone
- Cyclic(L-alanyl-D-threonyl-L-cysteinyl-cis-4-hydroxy-L-prolyl-L-alanyl-2-mercapto-L-tryptophyl-4,5-dihydroxy-L-leucyl),cyclic (3,6)-sulfide
- EINECS 241-484-5
- Phalloidin from Amanita phalloi
- Phalloidine
- Nsc523214
- pto-l-tryptophyl-4,5-dihydroxy-l-leucyl),cyclic(3,6)-sulfide
- Cyclo(L-Ala-D-Thr-L-Cys(1)-L-c4Hyp-L-Ala-L-Trp2(1)-4,5'-dihydroxy-L-Leu-)
- Phalloidin *CAS#: 17466-45-4*
- Phalloidin, 90%, from Amanita phalloides
- cyclic(l-alanyl-d-threonyl-l-cysteinyl-cis-4-hydroxy-l-prolyl-l-alanyl-2-merca
- NSC-523214
- 17466-45-4
- Phalloidin from Amanita phalloides, >=90%
- LS-15367
- Cyclic(L-alanyl-D-threonyl-L-cysteinyl-cis-4-hydroxy-L-prolyl-L-alanyl-2-mercapto-L-tryptophyl-4, cyclic (3.fwdarw.6)-sulfide
- NS00015477
- GTPL4736
- 28-(2,3-Dihydroxy-2-methylpropyl)-18-hydroxy-34-(1-hydroxyethyl)-23,31-dimethyl-12-thia-10,16,22,25,27,30,33,36-octazapentacyclo[12.11.11.03,11.04,9.016,20]hexatriaconta-3(11),4,6,8-tetraene-15,21,24,26,29,32,35-heptone
- SCHEMBL39329
- DTXSID3037254
- Phalloidin is known as a heptapeptide phallotoxin.
- SMP1_000234
- (2,3-dihydroxy-2-methyl-propyl)-hydroxy-(1-hydroxyethyl)-dimethyl-[?]heptone
- 28-(2,3-dihydroxy-2-methylpropyl)-18-hydroxy-34-(1-hydroxyethyl)-23,31-dimethyl-12-thia-10,16,22,25,27,30,33,36-octaazapentacyclo[12.11.11.0^{3,11}.0^{4,9}.0^{16,20}]hexatriaconta-3(11),4,6,8-tetraene-15,21,24,26,29,32,35-heptone
- J-011024
- Cyclo(L-alanyl-2-mercapto-L-tryptophanyl-4,5-dihydroxy-L-leucyl-L-alanyl-threonyl-cysteinyl-L-cis-4-hydroxy-L-prolyl, cyclic (2, 6)-sulfide
- SCHEMBL39330
- CYCLIC(L-ALANYL-D-THREONYL-L-CYSTEINYL-CIS-4-HYDROXY-L- PROLYL-L-ALANYL-2-MERCAPTO-L-TRYPTOPHYL-4,5-DIHYDROXY-L- LEUCYL), CYCLIC (3,6)-SULFIDE
- PHALLOIDINE [HSDB]
- (1S,14R,18S,20S,23S,28S,31S,34R)-28-[(2R)-2,3-dihydroxy-2-methylpropyl]-18-hydroxy-34-[(1S)-1-hydroxyethyl]-23,31-dimethyl-12-thia-10,16,22,25,27,30,33,36-octazapentacyclo[12.11.11.03,11.04,9.016,20]hexatriaconta-3(11),4,6,8-tetraene-15,21,24,26,29,32,35-heptone
- CYCLO(L-ALANYL-D-THREONYL-L-CYSTEINYL-(4S)-4-HYDROXY-L-PROLYL-L-ALANYL-2-MERCAPTO-L-TRYPTOPHYL-(4R)-4,5-DIHYDROXY-L-LEUCYL), CYCLIC (3->6)-THIOETHER
- NSC 523214
- 5A520O87TI
- Phalloidine (>80%)
- HSDB 3524
- (1S,14R,18S,20S,23S,28S,31S,34R)-28-[(2R)-2,3-dihydroxy-2-methylpropyl]-18-hydroxy-34-[(1S)-1-hydroxyethyl]-23,31-dimethyl-12-thia-10,16,22,25,27,30,33,36-octaazapentacyclo[12.11.11.0(3,11).0(4,9).0(16,20)]hexatriaconta-3(11),4,6,8-tetraene-15,21,24,26,29,32,35-heptone
- CHEBI:8040
- C08439
- Cyclic(L-alanyl-D-threonyl-L-cysteinyl-cis-4-hydroxy-L-prolyl-L-alanyl-2-mercapto-L-tryptophyl-4,5-dihydroxy-L-leucyl), cyclic (3,6)-sulfide
- PHALLOIDIN [MI]
- Q2266164
- BRN 4347460
- UNII-5A520O87TI
- KPKZJLCSROULON-UHFFFAOYSA-N
- Mast Cell Degranulating (MCD) Peptide
- DA-65261
-
- MDL： MFCD06201852
- Inchi： 1S/C35H48N8O11S/c1-15-27(47)38-22-10-20-19-7-5-6-8-21(19)41-33(20)55-13-24(34(53)43-12-18(46)9-25(43)31(51)37-15)40-32(52)26(17(3)45)42-28(48)16(2)36-30(50)23(39-29(22)49)11-35(4,54)14-44/h5-8,15-18,22-26,41,44-46,54H,9-14H2,1-4H3,(H,36,50)(H,37,51)(H,38,47)(H,39,49)(H,40,52)(H,42,48)
- InChI Key： KPKZJLCSROULON-UHFFFAOYSA-N
- SMILES： S1C2=C(C3C=CC=CC=3N2)CC2C(NC(C(NC(C)C(NC(C(C)O)C(NC(C1)C(N1CC(CC1C(NC(C)C(N2)=O)=O)O)=O)=O)=O)=O)CC(C)(CO)O)=O
Computed Properties
- Exact Mass: 788.31600
- Monoisotopic Mass: 788.316
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 11
- Hydrogen Bond Acceptor Count: 19
- Heavy Atom Count: 55
- Rotatable Bond Count: 4
- Complexity: 1510
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 10
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 317A^2
- Surface Charge: 0
- Tautomer Count: 324
- XLogP3: -1.7
Experimental Properties
- Color/Form: Uncertain
- Density: 1.1612 (rough estimate)
- Melting Point: 280-282°
- Boiling Point: 1370.5°Cat760mmHg
- Flash Point: 782.6°C
- Refractive Index: 1.7400 (estimate)
- Stability/Shelf Life: Stable. Incompatible with strong oxidizing agents.
- PSA: 316.92000
- LogP: -1.83500
- Solubility: Uncertain
- Merck: 13,7273
- Specific Rotation: +55.7°(D/20℃)(c=0.5,メタノール)
Phalloidin Security Information
-
Symbol:
- Signal Word：Danger
- Hazard Statement： H300 +H310 + H330
- Warning Statement： P260-P264-P280-P284-P301 + P310-P302 + P350
- Hazardous Material transportation number：UN 3462 6.1/PG 2
- WGK Germany：3
- Hazard Category Code： 26/27/28
- Safety Instruction： 22-28-36/37-45
- FLUKA BRAND F CODES：18
- RTECS：SE9800000
-
Hazardous Material Identification：
- HazardClass：6.1(a)
- PackingGroup：I
- Toxicity：LD50 i.m. in albino mice: 3.3 mg/g (Vogt); LD50 i.p. in mice: 2 mg/kg (Wieland, Wieland)
- Storage Condition：Powder -80°C 2 years ? -20°C 1 year In solvent -80°C 6 months ? -20°C 1 month
- Safety Term：6.1(a)
- Risk Phrases：R26/27/28
- Hazard Level：6.1(a)
Phalloidin Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| MedChemExpress | HY-P0028-1mg |
Phalloidin |
17466-45-4 | 98.46% | 1mg |
￥3600 | 2024-05-24 | |
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | P2141-1MG |
Phalloidin |
17466-45-4 | 1mg |
￥3496.46 | 2023-09-21 | ||
| BAI LING WEI Technology Co., Ltd. | 568167-1MG |
Phalloidin, 90%, from Amanita phalloides |
17466-45-4 | 90% | 1MG |
￥ 2849 | 2022-04-26 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | P911807-1mg |
Phalloidin |
17466-45-4 | 98% | 1mg |
￥5,800.00 | 2022-09-01 | |
| abcr | AB545343-1 mg |
Phalloidin Trifluoroacetate; . |
17466-45-4 | 1mg |
€263.70 | 2022-07-29 | ||
| Apollo Scientific | BIP0842-1mg |
Phalloidin |
17466-45-4 | 1mg |
￡210.00 | 2025-02-19 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | P31700-1mg |
Phalloidin |
17466-45-4 | 1mg |
￥5708.0 | 2021-09-08 | ||
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajci15626-1mg |
Phalloidin |
17466-45-4 | 98% | 1mg |
￥1776.00 | 2023-09-09 | |
| TRC | P294523-100μg |
Phalloidine |
17466-45-4 | 100μg |
$91.00 | 2023-05-17 | ||
| TRC | P294523-1mg |
Phalloidine (>80%) |
17466-45-4 | 1mg |
$ 509.00 | 2023-09-06 |
Phalloidin Suppliers
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:17466-45-4)Phalloidin
Order Number:A1201069
Stock Status:in Stock
Quantity:1mg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 02:44
Price ($):357.0
Email:[email protected]
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:17466-45-4)Phalloidin
Order Number:LE12211
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:06
Price ($):discuss personally
Email:[email protected]
Phalloidin Related Literature
-
Joo Chuan Yeo,Kenry Lab Chip, 2016,16, 4082-4090
-
Bo Wei,Zhenyu Liu,Chen Xie,Shu Yang,Wentao Tang,Aiwei Gu,Wing-Tak Wong,Ka-Leung Wong J. Mater. Chem. C, 2015,3, 12322-12327
-
Jing Yu,Yu-Qi Lyu,Jiapeng Liu,Mohammed B. Effat,Junxiong Wu J. Mater. Chem. A, 2019,7, 17995-18002
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M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
-
Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
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