Cas no 174264-62-1 (Benzenemethanol, 2-hydroxy-5-(trifluoromethoxy)-)

Benzenemethanol, 2-hydroxy-5-(trifluoromethoxy)-, is a fluorinated aromatic alcohol with a hydroxyl group at the 2-position and a trifluoromethoxy substituent at the 5-position of the benzene ring. This compound is of interest in synthetic chemistry due to its unique electronic and steric properties, imparted by the trifluoromethoxy group, which enhances lipophilicity and metabolic stability. The presence of both hydroxyl and trifluoromethoxy functionalities makes it a versatile intermediate for pharmaceuticals, agrochemicals, and specialty materials. Its structural features enable selective modifications, facilitating the development of bioactive molecules with improved binding affinity and pharmacokinetic profiles. The compound's stability under various reaction conditions further underscores its utility in advanced synthetic applications.
Benzenemethanol, 2-hydroxy-5-(trifluoromethoxy)- structure
174264-62-1 structure
Product Name:Benzenemethanol, 2-hydroxy-5-(trifluoromethoxy)-
CAS No:174264-62-1
MF:C8H7F3O3
MW:208.134593248367
CID:1359194
PubChem ID:11694149
Update Time:2025-10-15

Benzenemethanol, 2-hydroxy-5-(trifluoromethoxy)- Chemical and Physical Properties

Names and Identifiers

    • Benzenemethanol, 2-hydroxy-5-(trifluoromethoxy)-
    • CS-0378128
    • SCHEMBL1905592
    • OTEPOBZTTWZMFK-UHFFFAOYSA-N
    • 174264-62-1
    • 2-Hydroxy-5-(trifluoromethoxy)benzyl alcohol
    • 2-(hydroxymethyl)-4-(trifluoromethoxy)phenol
    • Inchi： 1S/C8H7F3O3/c9-8(10,11)14-6-1-2-7(13)5(3-6)4-12/h1-3,12-13H,4H2
    • InChI Key： OTEPOBZTTWZMFK-UHFFFAOYSA-N
    • SMILES： FC(OC1=CC=C(C(CO)=C1)O)(F)F

Computed Properties

  • Exact Mass: 208.03471
  • Monoisotopic Mass: 208.03472857g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 2
  • Complexity: 183
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.2
  • Topological Polar Surface Area: 49.7?2

Experimental Properties

  • PSA: 49.69

Benzenemethanol, 2-hydroxy-5-(trifluoromethoxy)- Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
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2-Hydroxy-5-(trifluoromethoxy)benzyl alcohol
 174264-62-1 97%
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