Cas no 168897-20-9 (4-2-(1-Pyrrolidinyl)ethylaniline)

4-2-(1-Pyrrolidinyl)ethylaniline is a versatile aromatic amine derivative featuring a pyrrolidine-substituted ethylamine side chain. This compound is valued for its structural properties, which make it a useful intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and specialty chemicals. The pyrrolidine moiety enhances solubility and reactivity, facilitating its incorporation into complex molecular frameworks. Its amine functionality allows for further derivatization, enabling applications in catalysis, ligand design, and drug discovery. The compound's stability and well-defined reactivity profile make it a reliable choice for research and industrial processes requiring precise functional group manipulation. Proper handling and storage under inert conditions are recommended to maintain its integrity.

4-2-(1-Pyrrolidinyl)ethylaniline structure

168897-20-9 structure

Product Name:4-2-(1-Pyrrolidinyl)ethylaniline

CAS No:168897-20-9

MF:C₁₂H₁₈N₂

MW:190.284722805023

MDL:MFCD04114507

CID:137021

PubChem ID:6487047

Update Time:2025-11-02

4-2-(1-Pyrrolidinyl)ethylaniline Chemical and Physical Properties

Names and Identifiers

- 4-(2-(Pyrrolidin-1-yl)ethyl)aniline
- 4-(2-pyrrolidin-1-ylethyl)aniline
- 4-(2-Pyrrolidin-1-yl-ethyl)-aniline
- 4-(2-Pyrrolidin-1-yl-ethyl)-phenylamine
- 4-(2-Pyrrolidin-1-yl-ethyl)-phenylaminedihydrochloride
- Benzenamine, 4-[2-(1-pyrrolidinyl)ethyl]-
- 4-(2-(pyrrolidin-1-yl)ethyl)benzenamine
- 4-(2-pyrrolidin-1-yl-ethyl)phenylamine
- 4-(2-pyrrolidinylethyl)phenylamine
- 4-(2-pyrrolidlin-1-yl-ethyl)-phenylamine
- 4-[2-(pyrrolidin-1-yl)ethyl]aniline
- TIMTEC-BB SBB010841
- 4-[2-(1-Pyrrolidinyl)ethyl]aniline
- 4-[2-(1-pyrrolidinyl)ethyl]aniline(SALTDATA: 2HCl)
- ASINEX-REAG BAS 06706100
- DTXSID80424583
- 4-(2-pyrrolidin-1ylethyl) aniline
- Benzenamine,4-[2-(1-pyrrolidinyl)ethyl]-
- J-010490
- AKOS000104474
- EN300-52460
- 4-[2-(1-Pyrrolidinyl)ethyl]aniline, AldrichCPR
- CS-0340628
- WAOKZNBDXFOXSA-UHFFFAOYSA-N
- AB18469
- 168897-20-9
- MFCD04114507
- Z335286636
- SCHEMBL1877934
- FT-0677662
- CHEMBL1624672
- C77959
- DB-064712
- STL259668
- 4-2-(1-Pyrrolidinyl)ethylaniline
- MDL： MFCD04114507
- Inchi： 1S/C12H18N2/c13-12-5-3-11(4-6-12)7-10-14-8-1-2-9-14/h3-6H,1-2,7-10,13H2
- InChI Key： WAOKZNBDXFOXSA-UHFFFAOYSA-N
- SMILES： N1(CCC2C=CC(=CC=2)N)CCCC1

Computed Properties

Exact Mass: 190.14700
Monoisotopic Mass: 190.146998583g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Heavy Atom Count: 14
Rotatable Bond Count: 3
Complexity: 156
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: 2
Topological Polar Surface Area: 29.3?2

Experimental Properties

Density: 1.055
Boiling Point: 314.9°C at 760 mmHg
Flash Point: 129.2°C
Refractive Index: 1.58
PSA: 29.26000
LogP: 2.42620

4-2-(1-Pyrrolidinyl)ethylaniline Security Information

Hazard Category Code： 36
Safety Instruction： 26
Hazardous Material Identification：
HazardClass：IRRITANT

4-2-(1-Pyrrolidinyl)ethylaniline Customs Data

HS CODE：2933990090
Customs Data：

China Customs Code:
2933990090

Overview:

2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

Declaration elements:

Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

Summary:

2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4-2-(1-Pyrrolidinyl)ethylaniline Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
SHANG HAI XIAN DING Biotechnology Co., Ltd.	018805-5g	4-(2-Pyrrolidin-1-yl-ethyl)-phenylamine	168897-20-9		5g	16256CNY	2021-05-08
SHANG HAI XIAN DING Biotechnology Co., Ltd.	018805-500mg	4-(2-Pyrrolidin-1-yl-ethyl)-phenylamine	168897-20-9		500mg	3055CNY	2021-05-08
SHANG HAI XIAN DING Biotechnology Co., Ltd.	018805-1g	4-(2-Pyrrolidin-1-yl-ethyl)-phenylamine	168897-20-9		1g	5005CNY	2021-05-08
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.	20R0030-1g	4-(2-Pyrrolidin-1-yl-ethyl)-aniline	168897-20-9	96%	1g	491.86CNY	2021-05-08
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.	20R0030-5g	4-(2-Pyrrolidin-1-yl-ethyl)-aniline	168897-20-9	96%	5g	1687.6CNY	2021-05-08
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.	20R0030-25g	4-(2-Pyrrolidin-1-yl-ethyl)-aniline	168897-20-9	96%	25g	4986.49CNY	2021-05-08
Chemenu	CM198995-5g	4-(2-Pyrrolidin-1-yl-ethyl)-phenylamine	168897-20-9	95%	5g	$825	2021-08-05
TRC	B292253-100mg	4-[2-(1-Pyrrolidinyl)ethyl]aniline	168897-20-9		100mg	$ 64.00	2023-04-18
TRC	B292253-500mg	4-[2-(1-Pyrrolidinyl)ethyl]aniline	168897-20-9		500mg	$ 87.00	2023-04-18
TRC	B292253-1g	4-[2-(1-Pyrrolidinyl)ethyl]aniline	168897-20-9		1g	$ 144.00	2023-04-18

4-2-(1-Pyrrolidinyl)ethylaniline Suppliers

Amadis Chemical Company Limited

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(CAS:168897-20-9)4-2-(1-Pyrrolidinyl)ethylaniline

Order Number:A811033

Stock Status:in Stock

Quantity:5g/25g/100g

Purity:99%

Pricing Information Last Updated:Friday, 30 August 2024 04:54

Price ($):305.0/1094.0/3504.0

Email:[email protected]

Product Official Link

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Additional information on 4-2-(1-Pyrrolidinyl)ethylaniline

4-2-(1-Pyrrolidinyl)ethylaniline (CAS 168897-20-9): A Versatile Chemical Intermediate for Modern Applications

4-2-(1-Pyrrolidinyl)ethylaniline (CAS 168897-20-9) is a specialized organic compound gaining attention in pharmaceutical and material science research. This amine derivative features a unique molecular structure combining an aromatic aniline group with a pyrrolidine moiety, making it valuable for drug discovery and functional material development.

The compound's chemical properties show excellent solubility in common organic solvents, with a molecular weight of 190.28 g/mol. Its dual functional groups allow for diverse chemical modifications, particularly useful in creating bioactive molecules. Recent studies highlight its potential in developing neurological therapeutics, aligning with current research trends in neurodegenerative disease treatment.

In pharmaceutical applications, 4-2-(1-Pyrrolidinyl)ethylaniline serves as a key building block for synthesizing compounds targeting dopamine receptors and serotonin transporters. The pyrrolidine-ethylaniline structure contributes to enhanced blood-brain barrier penetration, a crucial factor for central nervous system drugs. Researchers are particularly interested in its potential for developing novel cognitive enhancers and mood regulators.

The material science field utilizes this compound for creating advanced polymers with unique electronic properties. Its aromatic amine group enables participation in various polymerization reactions, while the pyrrolidine side chain introduces steric and electronic effects that modify material characteristics. These properties make it valuable for developing conductive materials and photoactive compounds used in organic electronics.

Market analysis shows growing demand for 4-2-(1-Pyrrolidinyl)ethylaniline among research institutions and specialty chemical manufacturers. The global market for pharmaceutical intermediates is projected to expand significantly, driven by increased R&D investment in neurological disorders and advanced materials. Quality standards for this compound typically require ≥98% purity, with strict control of impurity profiles for pharmaceutical applications.

From a synthetic chemistry perspective, the production of CAS 168897-20-9 involves multi-step organic synthesis with careful control of reaction conditions. Modern green chemistry approaches are being developed to improve the sustainability of its production, reducing environmental impact while maintaining high chemical yield and purity. These advancements address growing concerns about sustainable chemical manufacturing in the industry.

Storage and handling of 4-2-(1-Pyrrolidinyl)ethylaniline require standard precautions for amine compounds, including protection from moisture and oxidation. Proper chemical storage conditions typically involve airtight containers under inert atmosphere, with recommended temperature ranges varying by manufacturer specifications. These protocols ensure compound stability and long-term usability for research purposes.

Recent patent filings reveal innovative applications of 4-2-(1-Pyrrolidinyl)ethylaniline derivatives in medical imaging and diagnostic agents. The compound's ability to form stable complexes with various imaging probes makes it valuable for developing new contrast agents and radiopharmaceuticals. This aligns with current healthcare trends toward personalized medicine and advanced diagnostics.

Quality control for CAS 168897-20-9 typically involves advanced analytical techniques including HPLC analysis, mass spectrometry, and NMR spectroscopy. These methods verify chemical identity and ensure compliance with stringent pharmaceutical-grade standards. The analytical data also provides crucial information for researchers developing structure-activity relationships in drug discovery projects.

The future outlook for 4-2-(1-Pyrrolidinyl)ethylaniline appears promising, with potential applications expanding into bioconjugation chemistry and targeted drug delivery systems. As research continues into its biological activity and material properties, this compound is likely to maintain its importance as a versatile chemical intermediate in both academic and industrial settings.

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