Cas no 166602-13-7 (3,5-Bis(trifluoromethyl)piperidine)
3,5-Bis(trifluoromethyl)piperidine is a fluorinated heterocyclic compound featuring two trifluoromethyl groups at the 3 and 5 positions of the piperidine ring. This structural configuration imparts high electronegativity and lipophilicity, making it valuable in pharmaceutical and agrochemical applications where enhanced metabolic stability and bioavailability are required. The presence of trifluoromethyl groups also contributes to increased chemical and thermal stability. Its rigid piperidine backbone allows for precise steric control in synthesis, facilitating its use as a building block in medicinal chemistry for the development of bioactive molecules. The compound is particularly useful in the design of enzyme inhibitors and receptor modulators due to its strong electron-withdrawing properties.
166602-13-7 structure
Product Name:3,5-Bis(trifluoromethyl)piperidine
CAS No:166602-13-7
MF:C7H9F6N
MW:221.143482923508
CID:4610780
Update Time:2025-06-08
3,5-Bis(trifluoromethyl)piperidine Chemical and Physical Properties
Names and Identifiers
-
- 3,5-Bis(trifluoromethyl)piperidine
-
- Inchi: 1S/C7H9F6N/c8-6(9,10)4-1-5(3-14-2-4)7(11,12)13/h4-5,14H,1-3H2
- InChI Key: WNSWTDWANMVMDB-UHFFFAOYSA-N
- SMILES: N1CC(C(F)(F)F)CC(C(F)(F)F)C1
Computed Properties
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 14
- Rotatable Bond Count: 2
3,5-Bis(trifluoromethyl)piperidine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 094240-250mg |
3,5-Bis(trifluoromethyl)piperidine |
166602-13-7 | 250mg |
£165.00 | 2022-03-01 | ||
| Fluorochem | 094240-1g |
3,5-Bis(trifluoromethyl)piperidine |
166602-13-7 | 1g |
£371.00 | 2022-03-01 | ||
| TRC | T900330-25mg |
3,5-Bis(trifluoromethyl)piperidine |
166602-13-7 | 25mg |
$ 87.00 | 2023-04-16 | ||
| TRC | T900330-50mg |
3,5-bis(trifluoromethyl)piperidine |
166602-13-7 | 50mg |
$ 95.00 | 2022-06-02 | ||
| TRC | T900330-250mg |
3,5-Bis(trifluoromethyl)piperidine |
166602-13-7 | 250mg |
$ 0.00 | 2023-04-16 | ||
| A2B Chem LLC | AV17193-100mg |
3,5-Bis(trifluoromethyl)piperidine |
166602-13-7 | 95% | 100mg |
$221.00 | 2024-04-20 | |
| A2B Chem LLC | AV17193-500mg |
3,5-Bis(trifluoromethyl)piperidine |
166602-13-7 | 95% | 500mg |
$452.00 | 2024-04-20 | |
| A2B Chem LLC | AV17193-2.5g |
3,5-Bis(trifluoromethyl)piperidine |
166602-13-7 | 95% | 2.5g |
$1141.00 | 2024-04-20 | |
| A2B Chem LLC | AV17193-5g |
3,5-Bis(trifluoromethyl)piperidine |
166602-13-7 | 95% | 5g |
$2206.00 | 2024-04-20 | |
| A2B Chem LLC | AV17193-10g |
3,5-Bis(trifluoromethyl)piperidine |
166602-13-7 | 95% | 10g |
$4258.00 | 2024-04-20 |
3,5-Bis(trifluoromethyl)piperidine Related Literature
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Christopher B. Rodell,Christopher B. Highley,Minna H. Chen,Neville N. Dusaj,Chao Wang,Lin Han,Jason A. Burdick Soft Matter, 2016,12, 7839-7847
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Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
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Guiying Zhang,Maosheng Cheng,Yanni Li,Keliang Liu,Lifeng Cai Chem. Commun., 2013,49, 11086-11088
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Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
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