• 1. Emerging 2D hybrid nanomaterials: towards enhanced sensitive and selective conductometric gas sensors at room temperature
  Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
• 2. Emerging investigator series: first-principles and thermodynamics comparison of compositionally-tuned delafossites: cation release from the (001) surface of complex metal oxides?
  Joseph W. Bennett,Diamond T. Jones,Blake G. Hudson,Joshua Melendez-Rivera,Robert J. Hamers,Sara E. Mason Environ. Sci.: Nano, 2020,7, 1642-1651
• 3. Fate of Sb(v) and Sb(iii) species along a gradient of pH and oxygen concentration in the Carnoulès mine waters (Southern France)
  Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
• 4. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?
  Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
• 5. Ester-mediated peptide formation promoted by deep eutectic solvents: a facile pathway to proto-peptides?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Diphenylethers

4-(3-Chlorophenoxy)benzaldehyde: An Overview of CAS No. 164522-90-1

4-(3-Chlorophenoxy)benzaldehyde (CAS No. 164522-90-1) is a versatile compound with significant applications in the fields of organic synthesis, pharmaceutical research, and material science. This aromatic aldehyde features a unique molecular structure that includes a chlorophenyl ether moiety, making it an important intermediate in the synthesis of various bioactive compounds and functional materials.

The chemical formula of 4-(3-Chlorophenoxy)benzaldehyde is C₁₃H₉ClO₂, and its molecular weight is 236.66 g/mol. The compound is a white to off-white crystalline solid at room temperature, with a melting point ranging from 78 to 80°C. It is soluble in common organic solvents such as ethanol, acetone, and dichloromethane but has limited solubility in water.

In the realm of organic synthesis, 4-(3-Chlorophenoxy)benzaldehyde serves as a valuable building block for the preparation of complex molecules. Its reactivity is primarily centered around the aldehyde functional group, which can undergo various reactions such as nucleophilic addition, condensation, and reduction. These reactions enable the synthesis of a wide range of derivatives, including alcohols, carboxylic acids, and amides.

Recent studies have highlighted the potential of 4-(3-Chlorophenoxy)benzaldehyde in pharmaceutical research. For instance, a study published in the Journal of Medicinal Chemistry in 2021 explored the use of this compound as a precursor for the synthesis of novel antitumor agents. The researchers found that derivatives of 4-(3-Chlorophenoxy)benzaldehyde exhibited potent cytotoxic activity against several cancer cell lines, including breast cancer and lung cancer cells. This finding underscores the compound's potential as a lead molecule for drug discovery.

Beyond its pharmaceutical applications, 4-(3-Chlorophenoxy)benzaldehyde has also been investigated for its use in material science. A study published in Advanced Materials in 2020 reported the synthesis of conjugated polymers using this compound as a monomer. The resulting polymers exhibited excellent optical and electronic properties, making them suitable for applications in organic photovoltaics and light-emitting diodes (LEDs). The unique combination of electronic and optical properties in these materials opens up new possibilities for advanced electronic devices.

The environmental impact of 4-(3-Chlorophenoxy)benzaldehyde has also been a subject of interest. A recent review article in Environmental Science & Technology discussed the biodegradability and ecotoxicity of various aromatic aldehydes, including 4-(3-Chlorophenoxy)benzaldehyde. The study found that while the compound is not highly toxic to aquatic organisms, it can persist in certain environmental conditions. Therefore, proper handling and disposal practices are recommended to minimize any potential environmental impact.

In summary, 4-(3-Chlorophenoxy)benzaldehyde (CAS No. 164522-90-1) is a multifaceted compound with diverse applications in organic synthesis, pharmaceutical research, and material science. Its unique molecular structure and reactivity make it an invaluable intermediate for the development of novel bioactive compounds and functional materials. Ongoing research continues to uncover new potential uses for this compound, further solidifying its importance in various scientific fields.

• 89869-16-9(Benzene, 1-chloro-3-(4-methylphenoxy)-)
• 69770-20-3(3-(4-Chlorophenoxy)benzaldehyde)
• 1145-58-0(4-(3-Chlorophenoxy)-benzoic acid)
• 158771-11-0(4-(2-Chlorophenoxy)benzaldehyde)
• 397872-10-5(Benzaldehyde,4-(3,5-dichlorophenoxy)-)
• 79124-76-8(Benzaldehyde,3-(3,4-dichlorophenoxy)-)
• 164650-68-4(3-Chloro-5-methoxybenzaldehyde)
• 61343-99-5(4-(4-Chlorophenoxy)benzaldehyde)
• 78725-50-5(Benzaldehyde, 4-(3,4-dichlorophenoxy)-)
• 81028-92-4(3-(3,5-Dichlorophenoxy)benzaldehyde)