Cas no 1644-68-4 (2,3-Bis(trifluoromethyl)pyridine)

2,3-Bis(trifluoromethyl)pyridine is a fluorinated heterocyclic compound characterized by the presence of two trifluoromethyl groups at the 2- and 3-positions of the pyridine ring. This structure imparts high electron-withdrawing properties, enhancing reactivity in nucleophilic substitution and cross-coupling reactions. The compound is particularly valuable in pharmaceutical and agrochemical synthesis, where its trifluoromethyl groups contribute to improved metabolic stability and lipophilicity of target molecules. Its thermal and chemical stability makes it suitable for demanding reaction conditions. Additionally, the electron-deficient pyridine core facilitates applications in materials science, such as ligand design for catalysis. The compound is typically handled under inert conditions due to its sensitivity to moisture.
2,3-Bis(trifluoromethyl)pyridine structure
1644-68-4 structure
Product Name:2,3-Bis(trifluoromethyl)pyridine
CAS No:1644-68-4
MF:C7H3F6N
MW:215.095842599869
MDL:MFCD03093763
CID:83856
PubChem ID:87565200
Update Time:2025-10-14

2,3-Bis(trifluoromethyl)pyridine Chemical and Physical Properties

Names and Identifiers

    • 2,3-Bis(trifluoromethyl)pyridine
    • 2,3,4-TRIHYDROXYBENZOPHENONE
    • 2,3-Bis-trifluormethyl-pyridin
    • 2,3-bis-trifluoromethyl-pyridine
    • 2,3-Di(trifluormethyl)pyridin
    • 2,3-Bis(trfluoromethyl)pyridine
    • Pyridine, 2,3-bis(trifluoromethyl)-
    • PubChem7694
    • bis(trifluoromethyl)pyridine
    • RRNXYHYDSDAOFW-UHFFFAOYSA-N
    • Pyridine,2,3-bis(trifluoromethyl)-
    • 2,3-Bis(trifluoromethyl)pyridine #
    • STL557861
    • BBL104047
    • 8357AA
    • SBB095068
    • PC4028
    • RP26893
    • VP10532
    • FCH1321186
    • HC150200
    • 2,3-Bis(trifluoromethyl)pyridine, 96%
    • B2394
    • MFCD03093763
    • 1644-68-4
    • 2 pound not3-Bis(trifluoromethyl)pyridine
    • AKOS005063758
    • FD10467
    • J-506902
    • DTXSID70343471
    • FT-0609501
    • A810571
    • SCHEMBL8436654
    • PS-7941
    • DB-043592
    • MDL： MFCD03093763
    • Inchi： 1S/C7H3F6N/c8-6(9,10)4-2-1-3-14-5(4)7(11,12)13/h1-3H
    • InChI Key： RRNXYHYDSDAOFW-UHFFFAOYSA-N
    • SMILES： FC(C1=CC=CN=C1C(F)(F)F)(F)F
    • BRN： 1622028

Computed Properties

  • Exact Mass: 215.01700
  • Monoisotopic Mass: 215.017
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 7
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 0
  • Complexity: 195
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 2.7
  • Topological Polar Surface Area: 12.9

Experimental Properties

  • Color/Form: Liquid
  • Density: 1.498?g/mL?at 25?°C
  • Melting Point: 2°C(lit.)
  • Boiling Point: 158°C(lit.)
  • Flash Point: Degrees Fahrenheit:158°F
    Degrees Celsius:70°C
  • Refractive Index: n20/D 1.393
  • PSA: 12.89000
  • LogP: 3.11920
  • Solubility: Insoluble in water.

2,3-Bis(trifluoromethyl)pyridine Security Information

2,3-Bis(trifluoromethyl)pyridine Customs Data

  • HS CODE：2933399090
  • Customs Data：

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2,3-Bis(trifluoromethyl)pyridine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Fluorochem
010402-250mg
2,3-Bis(trifluoromethyl)pyridine
 1644-68-4 97%
250mg
 ￡23.00 2022-03-01
Fluorochem
010402-1g
2,3-Bis(trifluoromethyl)pyridine
 1644-68-4 97%
1g
 ￡45.00 2022-03-01
Fluorochem
010402-5g
2,3-Bis(trifluoromethyl)pyridine
 1644-68-4 97%
5g
 ￡139.00 2022-03-01
Fluorochem
010402-25g
2,3-Bis(trifluoromethyl)pyridine
 1644-68-4 97%
25g
 ￡624.00 2022-03-01
Alichem
A029002507-5g
2,3-Bis(trifluoromethyl)pyridine
 1644-68-4 95%
5g
 $158.80 2022-04-02
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.
R023473-1g
2，3-Bis(trifluoromethyl)pyridine,97%
 1644-68-4 97%
1g
 ￥177 2024-05-25
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.
R023473-250mg
2，3-Bis(trifluoromethyl)pyridine,97%
 1644-68-4 97%
250mg
 ￥214 2024-05-25
Matrix Scientific
007212-1g
2,3-Bis(trifluoromethyl)pyridine
 1644-68-4
1g
 $47.00 2023-09-09
Matrix Scientific
007212-5g
2,3-Bis(trifluoromethyl)pyridine
 1644-68-4
5g
 $146.00 2023-09-09
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.
665657-250MG
2,3-Bis(trifluoromethyl)pyridine
 1644-68-4 96%
250MG
 292.78 2021-05-17

2,3-Bis(trifluoromethyl)pyridine Related Literature

  • 1. Notes
    C.-Y. Chen,R. J. W. Le Fèvre,K. K. Chakravarti,U. G. Nayak,S. C. Bhattacharyya,V. K. Balakrishnan,R. K. Razdan,A. S. Kertes,P. J. Lloyd,J. A. Reader,P. W. G. Smith,N. Boden,J. Feeney,L. H. Sutcliffe,R. J. Ferrier,W. G. Overend,A. E. Ryan,Johannes Dale,Raymond Coulon,H. El Khadem,M. M. Abdel Rahman,G. Birch,C. W. Bird,J. H. Knox,J. M. C. Turner,M. C. Ganorkar,M. H. B. Stiddard,D. A. H. Taylor,S. Nadkarni,N. R. Williams,A. H. Jackson,A. E. Smith,J. McKechnie,D. S. Payne,W. Sim,W. J. Feast,R. Stephens J. Chem. Soc. 1965 3473

Related Categories

1644-68-4 (2,3-Bis(trifluoromethyl)pyridine) Related Products

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Suzhou Senfeida Chemical Co., Ltd
Shandong Feiyang Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Feiyang Chemical Co., Ltd
Zhangzhou Sinobioway Peptide Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Zhangzhou Sinobioway Peptide Co.,Ltd.
Xiamen PinR Bio-tech Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Xiamen PinR Bio-tech Co., Ltd.
Jiangsu Xinsu New Materials Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jiangsu Xinsu New Materials Co., Ltd