Cas no 1806531-03-2 (2,5-Bis(trifluoromethyl)-3-(difluoromethyl)pyridine)

2,5-Bis(trifluoromethyl)-3-(difluoromethyl)pyridine is a fluorinated pyridine derivative characterized by its high electron-withdrawing properties due to the presence of multiple fluorine substituents. This compound is particularly valuable in pharmaceutical and agrochemical research, where its trifluoromethyl and difluoromethyl groups enhance metabolic stability and lipophilicity. Its structural features make it a versatile intermediate for synthesizing bioactive molecules, including potential enzyme inhibitors or receptor modulators. The strong inductive effects of the fluorine substituents also contribute to improved binding affinity in target interactions. Additionally, the compound's stability under various reaction conditions allows for further functionalization, making it a useful building block in medicinal chemistry and material science applications.
2,5-Bis(trifluoromethyl)-3-(difluoromethyl)pyridine structure
1806531-03-2 structure
Product Name:2,5-Bis(trifluoromethyl)-3-(difluoromethyl)pyridine
CAS No:1806531-03-2
MF:C8H3F8N
MW:265.103349924088
CID:4801967
Update Time:2025-10-13

2,5-Bis(trifluoromethyl)-3-(difluoromethyl)pyridine Chemical and Physical Properties

Names and Identifiers

    • 2,5-Bis(trifluoromethyl)-3-(difluoromethyl)pyridine
    • Inchi: 1S/C8H3F8N/c9-6(10)4-1-3(7(11,12)13)2-17-5(4)8(14,15)16/h1-2,6H
    • InChI Key: HEFYYIYXOVEGSW-UHFFFAOYSA-N
    • SMILES: FC(C1=CC(C(F)(F)F)=CN=C1C(F)(F)F)F

Computed Properties

  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 9
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 1
  • Complexity: 257
  • XLogP3: 3.3
  • Topological Polar Surface Area: 12.9

2,5-Bis(trifluoromethyl)-3-(difluoromethyl)pyridine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A029002444-250mg
2,5-Bis(trifluoromethyl)-3-(difluoromethyl)pyridine
1806531-03-2 95%
250mg
$1,038.80 2022-03-31
Alichem
A029002444-500mg
2,5-Bis(trifluoromethyl)-3-(difluoromethyl)pyridine
1806531-03-2 95%
500mg
$1,685.00 2022-03-31
Alichem
A029002444-1g
2,5-Bis(trifluoromethyl)-3-(difluoromethyl)pyridine
1806531-03-2 95%
1g
$2,923.95 2022-03-31
Recommended suppliers
ASIACHEM I&E (JIANGSU) CO., LTD
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
ASIACHEM I&E (JIANGSU) CO., LTD
Yunnanjiuzhen
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Yunnanjiuzhen
Shandong Jing Kun Chemical Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Jing Kun Chemical Co.,Ltd.
SunaTech Inc.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
SunaTech Inc.
Jiangsu Xinsu New Materials Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jiangsu Xinsu New Materials Co., Ltd