Cas no 1628507-87-8 (1-4-(Dihydroxyboranyl)-3-fluorophenylcyclopropane-1-carboxylic acid)

1-4-(Dihydroxyboranyl)-3-fluorophenylcyclopropane-1-carboxylic acid is a boronic acid derivative featuring a cyclopropane-carboxylic acid scaffold with a fluorine substituent on the phenyl ring. This compound is of interest in medicinal chemistry and cross-coupling reactions due to its unique structural properties. The presence of the boronic acid group enables its use in Suzuki-Miyaura couplings, facilitating the synthesis of complex biaryl structures. The fluorine atom enhances metabolic stability and binding selectivity in drug design, while the cyclopropane ring contributes to conformational rigidity. This combination of functional groups makes it a versatile intermediate for pharmaceutical research and organoboron chemistry applications.
1-4-(Dihydroxyboranyl)-3-fluorophenylcyclopropane-1-carboxylic acid structure
1628507-87-8 structure
Product Name:1-4-(Dihydroxyboranyl)-3-fluorophenylcyclopropane-1-carboxylic acid
CAS No:1628507-87-8
MF:C10H10BFO4
MW:223.993406772614
MDL:MFCD21609530
CID:4609775
Update Time:2025-10-24

1-4-(Dihydroxyboranyl)-3-fluorophenylcyclopropane-1-carboxylic acid Chemical and Physical Properties

Names and Identifiers

    • 1-[4-(Dihydroxyboranyl)-3-fluorophenyl]cyclopropane-1-carboxylic acid
    • 1-(4-borono-3-fluorophenyl)cyclopropanecarboxylic acid
    • 1-(4-borono-3-fluorophenyl)cyclopropane-1-carboxylic acid
    • W2866
    • 1-[4-(dihydroxyboranyl)-3-fluorophenyl]-cyclopropane-1-carboxylic acid
    • 1-4-(Dihydroxyboranyl)-3-fluorophenylcyclopropane-1-carboxylic acid
    • MDL: MFCD21609530
    • Inchi: 1S/C10H10BFO4/c12-8-5-6(1-2-7(8)11(15)16)10(3-4-10)9(13)14/h1-2,5,15-16H,3-4H2,(H,13,14)
    • InChI Key: ZJKFGOYSWXSOAH-UHFFFAOYSA-N
    • SMILES: FC1=C(B(O)O)C=CC(=C1)C1(C(=O)O)CC1

Computed Properties

  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 3
  • Complexity: 293
  • Topological Polar Surface Area: 77.8

Experimental Properties

  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 445.8±55.0 °C at 760 mmHg
  • Flash Point: 223.4±31.5 °C
  • Vapor Pressure: 0.0±1.1 mmHg at 25°C

1-4-(Dihydroxyboranyl)-3-fluorophenylcyclopropane-1-carboxylic acid Security Information

1-4-(Dihydroxyboranyl)-3-fluorophenylcyclopropane-1-carboxylic acid Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A019124096-1g
1-(4-Borono-3-fluorophenyl)cyclopropanecarboxylic acid
1628507-87-8 95%
1g
1,019.20 USD 2021-06-16
TRC
D678930-10mg
1-[4-(Dihydroxyboranyl)-3-fluorophenyl]cyclopropane-1-carboxylic acid
1628507-87-8
10mg
$81.00 2023-05-18
TRC
D678930-25mg
1-[4-(Dihydroxyboranyl)-3-fluorophenyl]cyclopropane-1-carboxylic acid
1628507-87-8
25mg
$161.00 2023-05-18
TRC
D678930-50mg
1-[4-(Dihydroxyboranyl)-3-fluorophenyl]cyclopropane-1-carboxylic acid
1628507-87-8
50mg
$253.00 2023-05-18
TRC
D678930-100mg
1-[4-(Dihydroxyboranyl)-3-fluorophenyl]cyclopropane-1-carboxylic acid
1628507-87-8
100mg
$339.00 2023-05-18
abcr
AB309330-100 mg
1-[4-(Dihydroxyboranyl)-3-fluorophenyl]cyclopropane-1-carboxylic acid; 96%
1628507-87-8
100mg
€450.00 2023-04-26
abcr
AB309330-250 mg
1-[4-(Dihydroxyboranyl)-3-fluorophenyl]cyclopropane-1-carboxylic acid; 96%
1628507-87-8
250mg
€807.00 2023-04-26
abcr
AB309330-100mg
1-[4-(Dihydroxyboranyl)-3-fluorophenyl]cyclopropane-1-carboxylic acid, 96%; .
1628507-87-8 96%
100mg
€450.00 2025-04-20
abcr
AB309330-250mg
1-[4-(Dihydroxyboranyl)-3-fluorophenyl]cyclopropane-1-carboxylic acid, 96%; .
1628507-87-8 96%
250mg
€807.00 2025-04-20
Chemenu
CM210794-1g
1-(4-Borono-3-fluorophenyl)cyclopropanecarboxylic acid
1628507-87-8 95%
1g
$1564 2023-02-17

1-4-(Dihydroxyboranyl)-3-fluorophenylcyclopropane-1-carboxylic acid Related Literature

Additional information on 1-4-(Dihydroxyboranyl)-3-fluorophenylcyclopropane-1-carboxylic acid

Compound CAS No. 1628507-87-8: 1-4-(Dihydroxyboranyl)-3-fluorophenylcyclopropane-1-carboxylic Acid

The compound CAS No. 1628507-87-8, also known as 1-4-(Dihydroxyboranyl)-3-fluorophenylcyclopropane-1-carboxylic Acid, is a highly specialized organic molecule with significant potential in various scientific and industrial applications. This compound is characterized by its unique structure, which includes a cyclopropane ring, a fluorophenyl group, and a dihydroxyboranyl substituent. The combination of these functional groups makes it a versatile compound with intriguing chemical properties.

Recent advancements in synthetic chemistry have enabled the precise synthesis of this compound, leveraging cutting-edge methodologies such as transition metal-catalyzed coupling reactions and boron-based intermediates. The synthesis of 1-4-(Dihydroxyboranyl)-3-fluorophenylcyclopropane-1-carboxylic Acid involves a multi-step process that ensures high yield and purity. Researchers have reported that the incorporation of the dihydroxyboranyl group significantly enhances the compound's reactivity, making it an attractive candidate for various applications in materials science and drug discovery.

One of the most promising applications of this compound lies in its potential use as a building block in medicinal chemistry. The fluorophenyl group is known to impart lipophilicity and bioavailability to molecules, while the cyclopropane ring introduces strain that can be exploited for designing bioactive compounds. Recent studies have demonstrated that derivatives of this compound exhibit potent inhibitory activity against key enzymes involved in neurodegenerative diseases, such as beta-secretase (BACE1). This suggests that CAS No. 1628507-87-8 could serve as a lead compound for developing novel therapeutic agents.

In addition to its medicinal applications, 1-4-(Dihydroxyboranyl)-3-fluorophenylcyclopropane-1-carboxylic Acid has shown potential in materials science, particularly in the development of advanced polymers and coatings. The dihydroxyboranyl group provides opportunities for cross-linking and functionalization, enabling the creation of materials with tailored mechanical and thermal properties. Recent research has highlighted its use as a precursor for synthesizing boron-containing polymers with enhanced stability and conductivity.

The physical and chemical properties of this compound have been extensively studied, revealing insights into its stability, solubility, and reactivity under various conditions. For instance, studies have shown that the compound exhibits good thermal stability up to 200°C, making it suitable for high-temperature applications. Furthermore, its solubility in polar solvents such as DMF and DMSO facilitates its use in solution-based reactions.

From an environmental perspective, the synthesis and application of CAS No. 1628507-87-8 have been designed with sustainability in mind. Researchers have developed eco-friendly synthetic routes that minimize waste generation and reduce the use of hazardous reagents. These efforts align with the growing demand for green chemistry practices in the modern chemical industry.

In conclusion, CAS No. 1628507-87-8: 1-4-(Dihydroxyboranyl)-3-fluorophenylcyclopropane-1-carboxylic Acid is a multifaceted compound with immense potential across diverse fields. Its unique structure, combined with recent advancements in synthetic methodologies and application-oriented research, positions it as a key player in future scientific innovations.

Recommended suppliers
TAIXING JOXIN BIO-TEC CO.,LTD.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
TAIXING JOXIN BIO-TEC CO.,LTD.
Nanjing jingzhu bio-technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Nanjing jingzhu bio-technology Co., Ltd.
Zouping Mingyuan Import and Export Trading Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Zouping Mingyuan Import and Export Trading Co., Ltd
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Wuhan ChemNorm Biotech Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Wuhan ChemNorm Biotech Co.,Ltd.