Cas no 16283-36-6 (Zinc Salicylate Dihydrate)

Zinc Salicylate Dihydrate is a crystalline compound with the chemical formula Zn(C?H?O?)?·2H?O, combining zinc and salicylic acid in a stable dihydrate form. It exhibits notable antiseptic, anti-inflammatory, and astringent properties, making it valuable in dermatological and pharmaceutical applications. The compound’s dual functionality—derived from zinc’s wound-healing effects and salicylate’s keratolytic action—enhances its efficacy in treating skin conditions such as acne, eczema, and minor irritations. Its hydrous form ensures improved solubility and bioavailability compared to anhydrous variants. Zinc Salicylate Dihydrate is also utilized in cosmetic formulations and topical antiseptics, offering a balanced combination of stability, low toxicity, and therapeutic performance.
Zinc Salicylate Dihydrate structure
Zinc Salicylate Dihydrate structure
Product Name:Zinc Salicylate Dihydrate
CAS No:16283-36-6
MF:C14H10O6Zn
MW:339.63460111618
CID:50383
Update Time:2026-05-14

Zinc Salicylate Dihydrate Chemical and Physical Properties

Names and Identifiers

    • Zinc salicylate
    • zinc,2-carboxyphenolate
    • Salicylic acid,zinc salt
    • zinc 2-hydroxybenzoate
    • zinc bis(2-hydroxybenzoate)
    • Zinc disalicylate
    • zinc(salicylato)2
    • Zinc,bis(2-hydroxybenzoato-O1,O2)-, (T-4)-
    • Zinc, bis(salicylato)- (6CI,7CI,8CI)
    • Bis(salicylato)zinc
    • Bontron E 304
    • DNA (Fugu rubripes clone 024P08bG3 genomesurvey sequence)
    • E 304
    • GenBank AL025232
    • Zinc bis(salicylate)
    • Zincdisalicylate
    • Zinc Salicylate Dihydrate
    • MDL: MFCD00045820
    • Inchi: InChI=1S/2C7H6O3.3H2O.Zn/c2*8-6-4-2-1-3-5(6)7(9)10;;;;/h2*1-4,8H,(H,9,10);3*1H2;/q;;;;;+2/p-2
    • InChI Key: VIVYBCKORJTEEV-UHFFFAOYSA-L
    • SMILES: O.O.O.[Zn+2].O=C(C1=CC=CC=C1O)[O-].O=C(C1=CC=CC=C1O)[O-]

Computed Properties

  • Exact Mass: 337.97700
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 1
  • Complexity: 229
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • XLogP3: ?3.4
  • Topological Polar Surface Area: 23.8

Experimental Properties

  • Color/Form: White needle crystals or powder.
  • PSA: 93.06000
  • LogP: 2.02410
  • Solubility: Not determined

Zinc Salicylate Dihydrate Security Information

  • Hazardous Material transportation number:UN 3077 9/PG 3
  • WGK Germany:2
  • Safety Instruction: S26; S36/39; S60; S61
  • RTECS:DV1763000
  • Hazardous Material Identification: Xn N
  • Risk Phrases:R20/21/22; R41; R50

Zinc Salicylate Dihydrate Customs Data

  • HS CODE:2918230000
  • Customs Data:

    China Customs Code:

    2918230000

    Overview:

    2918230000 Other salicylic acid esters. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2918230000 other esters of salicylic acid and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Zinc Salicylate Dihydrate Related Literature

Additional information on Zinc Salicylate Dihydrate

Zinc Salicylate Dihydrate: A Comprehensive Overview

Zinc Salicylate Dihydrate, also known as CAS No. 16283-36-6, is a compound that has garnered significant attention in recent years due to its versatile applications and promising research outcomes. This compound, which is represented by the chemical formula C7H5O3Zn·2H2O, is a coordination complex formed between zinc ions and salicylic acid. The dihydrate form indicates the presence of two water molecules associated with each formula unit. Zinc Salicylate Dihydrate has been extensively studied for its potential in various fields, including pharmaceuticals, cosmetics, and food additives.

One of the key attributes of Zinc Salicylate Dihydrate is its ability to act as a bioavailable source of zinc. Zinc is an essential trace element that plays a critical role in numerous physiological processes, including immune function, enzyme activation, and DNA synthesis. The dihydrate form of Zinc Salicylate is particularly advantageous due to its high solubility in water, which enhances its bioavailability and makes it an ideal ingredient for dietary supplements and fortified foods. Recent studies have highlighted the importance of zinc in maintaining skin health, with Zinc Salicylate Dihydrate showing potential as an effective ingredient in anti-inflammatory and acne-fighting skincare products.

The synthesis of Zinc Salicylate Dihydrate typically involves the reaction of zinc salts with salicylic acid under controlled conditions. This process ensures the formation of a stable complex with optimal physical and chemical properties. The compound is characterized by its white crystalline powder appearance and mild odor. Its melting point and solubility characteristics make it suitable for incorporation into various formulations without compromising stability or efficacy.

Recent advancements in research have explored the antioxidant properties of Zinc Salicylate Dihydrate. Antioxidants are crucial in protecting cells from oxidative stress, which is associated with aging and various chronic diseases. Studies have demonstrated that Zinc Salicylate Dihydrate exhibits potent antioxidant activity, potentially making it a valuable addition to functional foods and nutraceuticals. Additionally, its ability to chelate metal ions has been leveraged in environmental applications, such as water treatment and heavy metal remediation.

In the cosmetics industry, Zinc Salicylate Dihydrate has gained popularity as an effective ingredient for combating acne and reducing inflammation. Its anti-inflammatory properties are attributed to its ability to inhibit pro-inflammatory cytokines and modulate cellular signaling pathways. Furthermore, its role in promoting wound healing has been explored in both topical and systemic applications, offering promising results for patients with chronic wounds or skin disorders.

The safety profile of Zinc Salicylate Dihydrate has also been extensively evaluated. Studies indicate that it is well-tolerated when used within recommended dosage limits. However, excessive intake may lead to gastrointestinal discomfort or zinc toxicity in rare cases. Regulatory bodies have established guidelines for the safe use of Zinc Salicylate Dihydrate in food and cosmetic products, ensuring consumer safety while promoting its widespread adoption.

Looking ahead, ongoing research continues to uncover new applications for Zinc Salicylate Dihydrate. Emerging studies are investigating its potential as a natural preservative in food products, leveraging its antimicrobial properties to extend shelf life without relying on synthetic additives. Additionally, advancements in nanotechnology are exploring the encapsulation of Zinc Salicylate Dihydrate to enhance its delivery efficiency and target-specific therapeutic effects.

In conclusion, Zinc Salicylate Dihydrate (CAS No. 16283-36-6) stands out as a multifaceted compound with significant potential across diverse industries. Its unique chemical properties, coupled with recent research findings, underscore its value as a bioavailable zinc source with antioxidant, anti-inflammatory, and antimicrobial attributes. As scientific understanding continues to evolve, Zinc Salicylate Dihydrate is poised to play an increasingly important role in advancing health and wellness solutions worldwide.

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