Cas no 16202-50-9 (2-Propenoic acid,3-(2-hydroxy-4-methoxyphenyl)-)
2-Propenoic acid,3-(2-hydroxy-4-methoxyphenyl)- Chemical and Physical Properties
Names and Identifiers
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- 2-Propenoic acid,3-(2-hydroxy-4-methoxyphenyl)-
- 3-(2-HYDROXY-4-METHOXY-PHENYL)-ACRYLIC ACID
- 3-(2-hydroxy-4-methoxyphenyl)prop-2-enoic acid
- 2-hydroxy-4-methoxycinnamic acid
- 16202-50-9
- 2-hydroxy-4-methoxy-cinnamic acid
- DTXSID60610169
- IKNVEOZIOFMENG-UHFFFAOYSA-N
- D87966
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- Inchi: 1S/C10H10O4/c1-14-8-4-2-7(9(11)6-8)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)
- InChI Key: IKNVEOZIOFMENG-UHFFFAOYSA-N
- SMILES: O(C)C1C=CC(C=CC(=O)O)=C(C=1)O
Computed Properties
- Exact Mass: 194.0579
- Monoisotopic Mass: 194.05790880g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 14
- Rotatable Bond Count: 3
- Complexity: 224
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 1
- XLogP3: 1.5
- Topological Polar Surface Area: 66.8?2
Experimental Properties
- PSA: 66.76
2-Propenoic acid,3-(2-hydroxy-4-methoxyphenyl)- Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A015016457-250mg |
2-Hydroxy-4-methoxycinnamic acid |
16202-50-9 | 97% | 250mg |
494.40 USD | 2021-06-18 | |
| Alichem | A015016457-500mg |
2-Hydroxy-4-methoxycinnamic acid |
16202-50-9 | 97% | 500mg |
855.75 USD | 2021-06-18 | |
| Alichem | A015016457-1g |
2-Hydroxy-4-methoxycinnamic acid |
16202-50-9 | 97% | 1g |
1,504.90 USD | 2021-06-18 |
2-Propenoic acid,3-(2-hydroxy-4-methoxyphenyl)- Related Literature
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Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
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Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
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Fereshteh Bayat Environ. Sci.: Nano, 2021,8, 367-389
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David White,Sean R. Stowell Biomater. Sci., 2017,5, 463-474
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Zhixia Liu,Tingjian Chen,Floyd E. Romesberg Chem. Sci., 2017,8, 8179-8182
Related Categories
- Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Cinnamic acids and derivatives Hydroxycinnamic acids
- Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Cinnamic acids and derivatives Hydroxycinnamic acids and derivatives Hydroxycinnamic acids
Additional information on 2-Propenoic acid,3-(2-hydroxy-4-methoxyphenyl)-
2-Propenoic acid, 3-(2-hydroxy-4-methoxyphenyl) and Its Significance in Modern Chemical Research
The compound with the CAS number 16202-50-9, identified as 2-Propenoic acid, 3-(2-hydroxy-4-methoxyphenyl), represents a fascinating molecule with a rich chemical structure that has garnered considerable attention in the field of pharmaceutical and biochemical research. This compound, characterized by its unique phenolic and carboxylic functional groups, exhibits promising properties that make it a valuable candidate for further exploration in drug development and synthetic chemistry.
The molecular structure of 2-Propenoic acid, 3-(2-hydroxy-4-methoxyphenyl) consists of an acrylic acid backbone substituted with a hydroxyl group at the 2-position and a methoxy group at the 4-position of a phenyl ring. This arrangement imparts significant reactivity and potential biological activity, making it a subject of intense interest among researchers aiming to develop novel therapeutic agents. The presence of both hydroxyl and methoxy groups enhances its versatility, allowing for diverse chemical modifications and functionalizations that can tailor its properties for specific applications.
In recent years, the study of polyphenolic derivatives has seen substantial growth due to their inherent biological activities. Compounds like 2-Propenoic acid, 3-(2-hydroxy-4-methoxyphenyl) are particularly noteworthy because they combine the structural features of phenols with the reactivity of carboxylic acids. This combination has been exploited in various research avenues, including the synthesis of antioxidants, anti-inflammatory agents, and even potential chemotherapeutic compounds. The phenolic moiety is well-known for its ability to scavenge free radicals and reduce oxidative stress, while the carboxylic acid group can participate in hydrogen bonding interactions, enhancing solubility and bioavailability.
One of the most compelling aspects of 2-Propenoic acid, 3-(2-hydroxy-4-methoxyphenyl) is its potential as a building block for more complex molecules. Researchers have leveraged its reactive sites to develop derivatives with enhanced pharmacological profiles. For instance, by introducing additional functional groups or coupling it with other bioactive entities, scientists have been able to create novel compounds with targeted effects. This modular approach to drug design is particularly valuable in medicinal chemistry, where precision and specificity are paramount.
TheCAS number 16202-50-9 provides a unique identifier for this compound, facilitating its recognition and study within the scientific community. This standardized naming system ensures that researchers worldwide can accurately reference and discuss this molecule, fostering collaboration and accelerating discovery. The compound’s entry in the Chemical Abstracts Service (CAS) database also includes valuable information such as synthesis methods, physical properties, and references to relevant literature. These resources are indispensable for anyone working with or studying 2-Propenoic acid, 3-(2-hydroxy-4-methoxyphenyl).
Recent advancements in computational chemistry have further enhanced our understanding of this compound’s behavior. Molecular modeling techniques allow researchers to predict how 2-Propenoic acid, 3-(2-hydroxy-4-methoxyphenyl) interacts with biological targets at the atomic level. These simulations can guide experimental design by identifying potential binding sites and predicting the efficacy of different derivatives. Such computational approaches are becoming increasingly integral to modern drug discovery pipelines, complementing traditional experimental methods.
The pharmacological potential of 2-Propenoic acid, 3-(2-hydroxy-4-methoxyphenyl) has been explored in several preclinical studies. Its structural features suggest that it may interfere with key cellular pathways involved in inflammation and cancer progression. For example, some preliminary research indicates that derivatives of this compound may inhibit enzymes such as cyclooxygenase (COX) or lipoxygenase (LOX), which are implicated in pain and inflammation. Additionally, its antioxidant properties could make it useful in combating oxidative damage associated with neurodegenerative diseases.
Another area where this compound shows promise is in the development of antimicrobial agents. The rise of antibiotic-resistant bacteria has necessitated the search for novel antimicrobial compounds with unique mechanisms of action. The phenolic and carboxylic groups in 2-Propenoic acid, 3-(2-hydroxy-4-methoxyphenyl) could potentially disrupt bacterial cell membranes or interfere with essential metabolic processes. Further investigation into its antimicrobial activity could uncover new strategies for combating infections caused by resistant pathogens.
The synthesis of 2-Propenoic acid, 3-(2-hydroxy-4-methoxyphenyl) is another area where significant progress has been made. Chemists have developed efficient routes to produce this compound using readily available starting materials. These synthetic methods often involve palladium-catalyzed cross-coupling reactions or other transition-metal-mediated processes that facilitate the introduction of functional groups at specific positions on the phenyl ring. Such advances in synthetic methodology are crucial for enabling large-scale production and further exploration of this molecule’s potential applications.
The role of natural products as inspiration for drug discovery cannot be overstated. Many polyphenolic compounds are found in plants and exhibit remarkable biological activities due to their complex structures. By studying natural products like flavonoids or stilbenes—compounds that share structural similarities with 2-Propenoic acid, 3-(2-hydroxy-4-methoxyphenyl)—scientists have gained valuable insights into their pharmacological effects. These insights can then be applied to design synthetic analogs with improved properties.
In conclusion,2-Propenoic acid, 3-(hydroxy-4-methoxyphenyl), identified by its CAS number 1620250-509, is a versatile molecule with significant potential in pharmaceutical research. Its unique structural features enable diverse chemical modifications and biological activities, making it a valuable candidate for drug development efforts aimed at treating various diseases ranging from inflammation to cancer. As research continues to uncover new applications for this compound,CAS no16202/50/9 will undoubtedly remain an important reference point for scientists working at the intersection of chemistry and medicine.
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