Cas no 33130-03-9 (2,3,4-Trimethoxycinnamic Acid)
2,3,4-Trimethoxycinnamic Acid is a methoxy-substituted derivative of cinnamic acid, characterized by its three methoxy groups at the 2, 3, and 4 positions of the phenyl ring. This compound is of interest in organic synthesis and pharmaceutical research due to its role as a versatile intermediate in the preparation of bioactive molecules, including flavonoids and other polyphenolic derivatives. Its methoxy groups enhance electron density, influencing reactivity in coupling and condensation reactions. The compound exhibits moderate solubility in polar organic solvents, facilitating its use in synthetic applications. Its structural features make it valuable for studying structure-activity relationships in medicinal chemistry and as a precursor for fine chemical synthesis.
2,3,4-Trimethoxycinnamic Acid structure
Product Name:2,3,4-Trimethoxycinnamic Acid
CAS No:33130-03-9
MF:C12H14O5
MW:238.236564159393
MDL:MFCD00014376
CID:54019
PubChem ID:87577699
Update Time:2025-06-07
2,3,4-Trimethoxycinnamic Acid Chemical and Physical Properties
Names and Identifiers
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- 3-(2,3,4-Trimethoxyphenyl)acrylic acid
- 2,3,4-Trimethoxycinnamic acid
- (trans)-2,3,4-Trimethoxycinnamic acid
- (2E)-3-(2,3,4-Trimethoxyphenyl)acrylic acid
- trans-2,3,4-Trimethoxycinnamic acid
- 2,3,4,5,6-PENTAFLUOROPHENYL PHENYLMETHANESULPHONATE
- 2,3,4-Trimethoxy-trans-cinnamic acid
- 2,3,4-Trimethoxyzimtsaeure
- RARECHEM BK HC T327
- Trans-2,3,4-Trimethoxycinnam
- trans-2,3,4-Trimethoxycinnamic
- LS-14076
- EINECS 251-388-5
- MFCD00014376
- 33130-03-9
- CHEBI:166597
- AC-8471
- W-106786
- 116406-19-0
- 3-(2,3,4-trimethoxyphenyl)-2-Propenoic acid
- 3-(2,3,4-trimethoxyphenyl)-2-Propenoate
- (2E)-3-(2,3,4-trimethoxyphenyl)prop-2-enoic acid
- (2E)-3-(2,3,4-Trimethoxyphenyl)-2-propenoic acid
- Trans-2, 3, 4-Trimethoxycinnamate
- NS00060390
- 2-Propenoic acid, 3-(2,3,4-trimethoxyphenyl)-
- (E)-3-(2,3,4-trimethoxyphenyl)acrylicacid
- AMY3942
- (E)-3-(2,3,4-trimethoxyphenyl)prop-2-enoic acid
- EN300-1457067
- AC-11307
- SCHEMBL285231
- (2E)-3-(2,3,4-Trimethoxyphenyl)-2-propenoic acid #
- (2E)-3-(2,3,4-Trimethoxyphenyl)-2-propenoate
- MS-8958
- AKOS000145321
- trans-3-(2,3,4-Trimethoxyphenyl)-2-propenoic acid
- T2016
- 2-Propenoic acid,3-(2,3,4-trimethoxyphenyl)-
- (E)-3-(2,3,4-trimethoxyphenyl)acrylic acid
- EN300-1856238
- SCHEMBL285232
- 3-(2,3,4-trimethoxyphenyl)prop-2-enoic acid
- 2-propenoic acid, 3-(2,3,4-trimethoxyphenyl)-, (2E)-
- ALBB-021133
- BBL027804
- STK698033
- 2,3,4-Trimethoxycinnamic Acid
-
- MDL： MFCD00014376
- Inchi： 1S/C12H14O5/c1-15-9-6-4-8(5-7-10(13)14)11(16-2)12(9)17-3/h4-7H,1-3H3,(H,13,14)/b7-5+
- InChI Key： ZYOPDNLIHHFGEC-FNORWQNLSA-N
- SMILES： O(C)C1C(=C(C=CC=1/C=C/C(=O)O)OC)OC
- BRN： 2657904
Computed Properties
- Exact Mass: 238.08400
- Monoisotopic Mass: 238.084
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 17
- Rotatable Bond Count: 5
- Complexity: 271
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 1
- Undefined Bond Stereocenter Count: 0
- Surface Charge: -1
- XLogP3: 2.4
- Topological Polar Surface Area: 67.8
Experimental Properties
- Color/Form: Powder
- Density: 1.1416 (rough estimate)
- Melting Point: 170.0 to 175.0 deg-C
- Boiling Point: 300.83°C (rough estimate)
- Flash Point: 149.7±20.0 °C
- Refractive Index: 1.4571 (estimate)
- PSA: 64.99000
- LogP: 1.81020
- Solubility: Insoluble in water
2,3,4-Trimethoxycinnamic Acid Security Information
-
Symbol:
- Prompt：warning
- Signal Word：Warning
- Hazard Statement： H315,H319,H335
- Warning Statement： P261,P305+P351+P338,P302+P352,P321,P405,P501
- Hazard Category Code： R36/37/38
- Safety Instruction： S37/39-S26
-
Hazardous Material Identification：
- Safety Term：S26;S37/39
- Risk Phrases：R36/37/38
- Storage Condition：Store at 4°C,-4At ℃Store…Better
2,3,4-Trimethoxycinnamic Acid Customs Data
- HS CODE：2918990090
- Customs Data：
China Customs Code:
2918990090Overview:
2918990090. Other additional oxy carboxylic acids(Including anhydrides\Acyl halide\Peroxides, peroxyacids and derivatives of this tax number). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
2,3,4-Trimethoxycinnamic Acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | T818589-5g |
trans-2,3,4-Trimethoxycinnamic acid |
33130-03-9 | 97% | 5g |
186.00 | 2021-05-17 | |
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | TN6666-100 mg |
trans-2,3,4-Trimethoxycinnamic acid |
33130-03-9 | 100MG |
￥740.00 | 2022-04-26 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | T23770-25g |
3-(2,3,4-Trimethoxyphenyl)acrylic acid |
33130-03-9 | 97% | 25g |
￥488.0 | 2023-09-06 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | T23770-5g |
3-(2,3,4-Trimethoxyphenyl)acrylic acid |
33130-03-9 | 97% | 5g |
￥168.0 | 2023-09-06 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R002648-25g |
2,3,4-Trimethoxycinnamic Acid |
33130-03-9 | 98% | 25g |
￥245 | 2024-05-24 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R002648-5g |
2,3,4-Trimethoxycinnamic Acid |
33130-03-9 | 98% | 5g |
￥66 | 2024-05-24 | |
| Fluorochem | 011242-5g |
2,3,4-Trimethoxycinnamic acid |
33130-03-9 | 95% | 5g |
￡81.00 | 2022-03-01 | |
| Fluorochem | 011242-25g |
2,3,4-Trimethoxycinnamic acid |
33130-03-9 | 95% | 25g |
￡243.00 | 2022-03-01 | |
| Fluorochem | 011242-100g |
2,3,4-Trimethoxycinnamic acid |
33130-03-9 | 95% | 100g |
￡663.00 | 2022-03-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | T101268-5g |
2,3,4-Trimethoxycinnamic Acid |
33130-03-9 | 97% | 5g |
￥60.90 | 2023-09-01 |
2,3,4-Trimethoxycinnamic Acid Suppliers
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:33130-03-9)2,3,4-Trimethoxycinnamic Acid
Order Number:A821631
Stock Status:in Stock
Quantity:500g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 16:09
Price ($):350.0
Email:[email protected]
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:33130-03-9)trans-2,3,4-Trimethoxycinnamic acid
Order Number:sfd18753
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:38
Price ($):discuss personally
Email:[email protected]
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:33130-03-9)2,3,4-Trimethoxycinnamic Acid, ≥ 97.0%
Order Number:LE14464;LE2468677
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:10
Price ($):discuss personally
Email:[email protected]
2,3,4-Trimethoxycinnamic Acid Related Literature
-
Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
-
Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
-
Brindha J.,Balamurali M. M.,Kaushik Chanda RSC Adv., 2019,9, 34720-34734
-
Ivor Lon?ari? Phys. Chem. Chem. Phys., 2015,17, 9436-9445
Related Categories
- Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Cinnamic acids and derivatives Coumaric acids and derivatives
- Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Cinnamic acids and derivatives Hydroxycinnamic acids and derivatives Coumaric acids and derivatives
- Solvents and Organic Chemicals Organic Compounds Acids/Esters
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