Production Method 1

845959-53-7

16053-58-0

444890-41-9

Reaction Conditions

1.1 Reagents: Sodium borohydride Solvents: Methanol ;  30 min, cooled; 30 min, cooled
1.2 Reagents: Hydrochloric acid Solvents: Water ;  acidified
1.3 Solvents: 1,4-Dioxane ;  72 h, reflux
1.4 Reagents: Oxygen Solvents: Ethanol ;  48 h, rt

Reference

Effect of mitoquinone on liver metabolism and steatosis in obese and diabetic rats

Fink, Brian D.; Yu, Liping; Coppey, Lawrence; Obrosov, Alexander; Shevalye, Hanna; et al, Pharmacology Research & Perspectives, 2021, 9(1),

Methanesulfonic acid,ion(1-) (8CI,9CI) Raw materials

• 10-(4,5-Dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dienyl)decyl methanesulfonate

Methanesulfonic acid,ion(1-) (8CI,9CI) Preparation Products

• Mitoquinone (444890-41-9)
• Methanesulfonic acid,ion(1-) (8CI,9CI) (16053-58-0)

• 1. Effects of acidity and immiscibility of lactam-based Br?nsted-acidic ionic liquids on their catalytic performance for esterification
  Hancheng Zhou,Jing Yang,Linmin Ye,Haiqiang Lin,Youzhu Yuan Green Chem. 2010 12 661
• 2. Methanesulfonate and p-toluenesulfonate salts of the N-methyl-N-alkylpyrrolidinium and quaternary ammonium cations: novel low cost ionic liquids
  J. Golding,S. Forsyth,D. R. MacFarlane,M. Forsyth,G. B. Deacon. Green Chem. 2002 4 223
• 3. Antibiofilm activity of tert-BuOH functionalized ionic liquids with methylsulfonate counteranions
  Govinda R. Navale,Mahesh S. Dharne,Sandip S. Shinde RSC Adv. 2015 5 68136
• 4. Design and preparation of new palladium precatalysts for C–C and C–N cross-coupling reactions
  Nicholas C. Bruno,Matthew T. Tudge,Stephen L. Buchwald Chem. Sci. 2013 4 916
• 5. Design and preparation of new palladium precatalysts for C–C and C–N cross-coupling reactions
  Nicholas C. Bruno,Matthew T. Tudge,Stephen L. Buchwald Chem. Sci. 2013 4 916

• 2386-56-3(Potassium methanesulfonate)
• 75-75-2(Methanesulfonic acid)
• 22515-76-0(Methanesulfonic acid, Ammonium Salt)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)