• 1. An atom efficient route to N-aryl and N-alkyl pyrrolines by transition metal catalysis?
  Supaporn Sawadjoon,Joseph S. M. Samec Org. Biomol. Chem., 2011,9, 2548-2554
• 2. Alternative donor substrates for inverting and retaining glycosyltransferases?
  Luke L. Lairson,Warren W. Wakarchuk Chem. Commun., 2007, 365-367
• 3. An alumina stabilized graphene oxide wrapped SnO2 hollow sphere LIB anode with improved lithium storage?
  Xiang Liu,Qian Sun,A. B. Djuri?i?,Maohai Xie,Baohu Dai,Jinyao Tang,Charles Surya,Changzhong Liao,Kaimin Shih RSC Adv., 2015,5, 100783-100789
• 4. An analyte-triggered artificial peroxidase system based on dimanganese complex for a versatile enzyme assay?
  Suji Lee,Min Su Han Chem. Commun., 2021,57, 9450-9453
• 5. An all-solid-state asymmetric device based on a polyaniline hydrogel for a high energy flexible supercapacitor?
  Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzene and substituted derivatives
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives

Benzeneacetonitrile, 4-Ethenyl- (CAS No. 1592-11-6): An Overview of Its Properties, Applications, and Recent Research

Benzeneacetonitrile, 4-ethenyl- (CAS No. 1592-11-6) is a versatile organic compound with a wide range of applications in the chemical and pharmaceutical industries. This compound, also known as 4-Vinylbenzyl cyanide, is characterized by its unique chemical structure, which includes a benzene ring substituted with a cyano group and a vinyl group. The combination of these functional groups endows the compound with valuable properties that make it an important intermediate in various synthetic processes.

The molecular formula of Benzeneacetonitrile, 4-ethenyl- is C₉H₇N, and its molecular weight is approximately 129.15 g/mol. The compound is a colorless liquid at room temperature and has a boiling point of around 230°C. It is soluble in common organic solvents such as ethanol, acetone, and dichloromethane but has limited solubility in water.

In the field of organic synthesis, Benzeneacetonitrile, 4-ethenyl- serves as a valuable building block for the preparation of more complex molecules. Its reactivity is primarily centered around the cyano group, which can undergo various transformations such as hydrolysis to form carboxylic acids, reduction to generate amines, and nucleophilic substitution reactions. The vinyl group also provides opportunities for polymerization and other addition reactions, making this compound particularly useful in the synthesis of polymers and other functional materials.

Recent research has highlighted the potential applications of Benzeneacetonitrile, 4-ethenyl- in the development of new materials and pharmaceuticals. For instance, studies have shown that derivatives of this compound can be used as precursors for the synthesis of advanced polymers with enhanced mechanical and thermal properties. These polymers find applications in areas such as coatings, adhesives, and electronic materials.

In the pharmaceutical industry, Benzeneacetonitrile, 4-ethenyl- has been explored as an intermediate in the synthesis of various drugs. One notable example is its use in the preparation of certain antiviral agents. The cyano group can be transformed into functional groups that are crucial for the biological activity of these drugs. Additionally, the vinyl group can be utilized to introduce additional functionalities that enhance the drug's efficacy or pharmacokinetic properties.

The environmental impact of Benzeneacetonitrile, 4-ethenyl- has also been a subject of recent research. Studies have shown that this compound can be biodegraded under certain conditions, which is an important consideration for its industrial use. However, proper handling and disposal practices are still necessary to minimize any potential environmental risks.

In terms of safety, while Benzeneacetonitrile, 4-ethenyl- is generally considered safe for industrial use when proper precautions are taken, it is important to handle it with care due to its reactivity and potential health effects. Personal protective equipment (PPE) such as gloves and goggles should be worn when handling this compound to prevent skin contact and inhalation.

The market demand for Benzeneacetonitrile, 4-ethenyl- continues to grow due to its diverse applications in various industries. Key players in the chemical industry are investing in research and development to explore new uses for this compound and improve its production processes. This ongoing innovation is expected to drive further growth in the market for Benzeneacetonitrile, 4-ethenyl- in the coming years.

In conclusion, Benzeneacetonitrile, 4-ethenyl- (CAS No. 1592-11-6) is a multifunctional organic compound with significant potential in both industrial and pharmaceutical applications. Its unique chemical structure and reactivity make it an invaluable intermediate in synthetic chemistry. As research continues to uncover new uses for this compound, it is likely to play an increasingly important role in the development of advanced materials and drugs.

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