Cas no 158553-98-1 (Cl-PEG4-acid)

Cl-PEG4-acid is a heterobifunctional polyethylene glycol (PEG) derivative featuring a terminal carboxylic acid and a chloro group, separated by a tetraethylene glycol spacer. This compound is widely used in bioconjugation and crosslinking applications due to its hydrophilic PEG backbone, which enhances solubility and reduces immunogenicity. The chloro group serves as a reactive handle for nucleophilic substitution, while the carboxylic acid enables amide bond formation with amines via activation. The PEG4 spacer provides optimal length for flexibility and steric accessibility. Cl-PEG4-acid is particularly valuable in peptide synthesis, antibody-drug conjugates (ADCs), and surface functionalization, offering controlled reactivity and improved biocompatibility in aqueous and organic media.
Cl-PEG4-acid structure
Cl-PEG4-acid structure
Product Name:Cl-PEG4-acid
CAS No:158553-98-1
MF:C10H19ClO6
MW:270.707263231277
CID:1336750
PubChem ID:86177859
Update Time:2025-10-17

Cl-PEG4-acid Chemical and Physical Properties

Names and Identifiers

    • 3,6,9,12-Tetraoxatetradecanoic acid, 14-chloro-
    • Cl-PEG4-acid
    • Acetic acid, 2-[2-[2-[2-(2-chloroethoxy)ethoxy]ethoxy]ethoxy]-
    • MS-23833
    • HY-W096129
    • D84699
    • CS-0147799
    • DA-72287
    • SCHEMBL18173867
    • Cl-PEG4-CH2COOH
    • 2-[2-[2-[2-(2-chloroethoxy)ethoxy]ethoxy]ethoxy]acetic acid
    • 158553-98-1
    • AKOS040756909
    • 14-Chloro-3,6,9,12-tetraoxatetradecanoic acid
    • Inchi： 1S/C10H19ClO6/c11-1-2-14-3-4-15-5-6-16-7-8-17-9-10(12)13/h1-9H2,(H,12,13)
    • InChI Key： XBWVBVYMGRKKOO-UHFFFAOYSA-N
    • SMILES： ClCCOCCOCCOCCOCC(=O)O

Computed Properties

  • Exact Mass: 270.08707
  • Monoisotopic Mass: 270.0870160 g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 13
  • Complexity: 178
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Molecular Weight: 270.71
  • XLogP3: -0.2
  • Topological Polar Surface Area: 74.2?2

Experimental Properties

  • PSA: 74.22

Cl-PEG4-acid Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
eNovation Chemicals LLC
Y1241668-100mg
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 158553-98-1 97%
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eNovation Chemicals LLC
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Cl-PEG4-CH2COOH
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eNovation Chemicals LLC
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MedChemExpress
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 ￥410 2024-04-19
MedChemExpress
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MedChemExpress
HY-W096129-100mg
Cl-PEG4-acid
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SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
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Cl-PEG4-acid
 158553-98-1 97%
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 ￥1,350.00 2022-09-29
Biosynth
IGA55398-100 mg
Cl-PEG4-acid
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100MG
 $90.00 2023-01-04
Biosynth
IGA55398-250 mg
Cl-PEG4-acid
 158553-98-1
250MG
 $170.00 2023-01-04
Biosynth
IGA55398-500 mg
Cl-PEG4-acid
 158553-98-1
500MG
 $270.00 2023-01-04

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