• 1. An integrated droplet-digital microfluidic system for on-demand droplet creation, mixing, incubation, and sorting?
  Lab Chip, 2019,19, 524-535
• 2. An integrated cathode and solid electrolyte via in situ polymerization with significantly reduced interface resistance?
  Jialiang Yuan,Ran Dong,Yuan Li,Yang Liu,Zhuo Zheng,Yuxia Liu,Yan Sun,Benhe Zhong,Zhenguo Wu,Xiaodong Guo Chem. Commun., 2021,57, 13004-13007
• 3. An artificial blood vessel implanted three-dimensional microsystem for modeling transvascular migration of tumor cells?
  Xue-Ying Wang,Ying Pei,Min Xie,Zi-He Jin,Ya-Shi Xiao,Yang Wang,Li-Na Zhang,Yan Li,Wei-Hua Huang Lab Chip, 2015,15, 1178-1187
• 4. An air-stable organometallic polymer containing titanafluorene moieties obtained by the Sonogashira–Hagihara cross-coupling polycondensation?
  Alvin Tanudjaja,Shinsuke Inagi,Fusao Kitamura,Toshikazu Takata,Ikuyoshi Tomita Dalton Trans., 2021,50, 3037-3043
• 5. An investigation on the second-order nonlinear optical response of cationic bipyridine or phenanthroline iridium(iii) complexes bearing cyclometallated 2-phenylpyridines with a triphenylamine substituent?
  David B. Cordes,Alexandra M. Z. Slawin,Stefania Righetto,Denis Jacquemin,Eli Zysman-Colman,Véronique Guerchais Dalton Trans., 2018,47, 8292-8300

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Carboxylic acids

2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]acetic Acid (CAS No. 396106-50-6): Properties, Applications, and Industry Insights

2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]acetic Acid (CAS No. 396106-50-6) is a specialized organic compound with a unique molecular structure that combines ether and carboxylic acid functionalities. This chloroethoxy acetic acid derivative has gained significant attention in recent years due to its versatile applications in pharmaceutical intermediates, polymer chemistry, and specialty chemical synthesis. The compound's systematic name reflects its branched ethoxy chain terminated by a chloroethoxy group and an acetic acid moiety, making it particularly valuable for controlled-release formulations and surface modification technologies.

The chemical industry has shown growing interest in polyether carboxylic acids like 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]acetic Acid due to their ability to serve as building blocks for more complex molecular architectures. Recent studies highlight its potential in creating pH-responsive materials, a hot topic in smart material research. The compound's ethylene oxide chains provide water solubility, while the terminal chloro group offers reactive sites for further chemical modifications, answering frequent search queries about "water-soluble reactive intermediates" and "functionalized polyethers."

From a synthetic chemistry perspective, CAS 396106-50-6 demonstrates remarkable utility in creating PEGylated compounds, addressing the pharmaceutical industry's demand for improved drug delivery systems. The compound's triethylene glycol backbone with a chloroethoxy terminus makes it particularly suitable for conjugation reactions, a fact that aligns with trending searches about "bioconjugation chemistry" and "PEGylation techniques." Researchers have explored its use in creating hydrogel precursors, responding to the growing market for biocompatible materials in medical applications.

The physical properties of 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]acetic Acid contribute to its industrial relevance. As a liquid polyether derivative at room temperature, it offers handling advantages in manufacturing processes. Its balanced hydrophilicity-lipophilicity character makes it valuable for formulating amphiphilic compounds, a key search term in surfactant chemistry. The compound's molecular weight of 240.68 g/mol and moderate viscosity position it as an ideal candidate for precision chemical synthesis applications.

Environmental considerations surrounding chloroethoxy compounds have led to innovative approaches in the application of 396106-50-6. Recent developments focus on its use in creating biodegradable polymer additives, addressing frequent queries about "green chemistry alternatives." The compound's ability to serve as a reactive spacer in macromolecular design has been particularly valuable in developing sustainable material solutions, aligning with current industry trends toward circular economy principles.

Quality control aspects of 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]acetic Acid production have become increasingly important, as evidenced by search trends for "high-purity specialty chemicals." Advanced analytical techniques including HPLC purity testing and spectroscopic characterization ensure batch-to-batch consistency for this polyether carboxylic acid. The compound typically appears as a colorless to pale yellow liquid with characteristic physicochemical properties that make it distinguishable from similar materials in the ethoxy acetic acid family.

Market intelligence reveals growing demand for CAS 396106-50-6 across multiple sectors. Pharmaceutical applications dominate current usage, particularly in developing targeted drug delivery systems—a hot topic in medical research. The material science sector utilizes this compound for creating functionalized surfaces and smart coatings, responding to searches about "surface modification technologies." Emerging applications in electronic materials and advanced lubricants suggest future growth potential for this versatile chemical intermediate.

Safety and handling protocols for 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]acetic Acid follow standard practices for reactive organic compounds. While not classified as hazardous under normal conditions, proper storage in chemical-resistant containers and use of appropriate personal protective equipment are recommended—information frequently sought by laboratory professionals. The compound's chemical stability under controlled conditions and compatibility with common solvents make it relatively straightforward to work with in industrial settings.

Future research directions for 396106-50-6 appear promising, particularly in nanotechnology applications. The compound's molecular architecture lends itself to creating nanocarrier systems, a trending topic in drug delivery research. Additional exploration areas include its potential in ionic liquid formulations and as a ligand precursor in coordination chemistry—subjects generating increasing search traffic in academic circles. These developments position 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]acetic Acid as a compound with expanding scientific and commercial relevance.

In conclusion, 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]acetic Acid (CAS No. 396106-50-6) represents a valuable polyether carboxylic acid derivative with diverse applications across multiple industries. Its unique combination of ether linkages, terminal chloro group, and carboxylic acid functionality make it particularly useful for creating advanced materials and pharmaceutical intermediates. As research continues to uncover new applications for this specialty chemical, its market importance is likely to grow, especially in fields prioritizing molecular precision and functional versatility.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)