Cas no 15568-97-5 (tetramethyl-1,3-dioxane-4,6-dione)

Tetramethyl-1,3-dioxane-4,6-dione is a cyclic diester compound with applications in organic synthesis and polymer chemistry. Its rigid dioxane-dione structure provides stability and reactivity, making it useful as a precursor for specialty chemicals and crosslinking agents. The tetramethyl substitution enhances solubility in organic solvents while maintaining thermal stability. This compound is particularly valued for its ability to participate in controlled polymerization reactions, contributing to the synthesis of tailored polymeric materials. Its high purity and consistent performance make it suitable for research and industrial applications requiring precise molecular control. The compound’s stability under various conditions ensures reliable handling and storage.
tetramethyl-1,3-dioxane-4,6-dione structure
15568-97-5 structure
Product Name:tetramethyl-1,3-dioxane-4,6-dione
CAS No:15568-97-5
MF:C8H12O4
MW:172.178483009338
CID:1334297
PubChem ID:380817
Update Time:2025-06-14

tetramethyl-1,3-dioxane-4,6-dione Chemical and Physical Properties

Names and Identifiers

    • 1,3-Dioxane-4,6-dione, 2,2,5,5-tetramethyl-
    • 2,2,5,5-tetramethyl-1,3-dioxane-4,6-dione
    • tetramethyl-1,3-dioxane-4,6-dione
    • Z1198163865
    • AT31004
    • 15568-97-5
    • DB-111675
    • SCHEMBL1562353
    • CHEMBL1998219
    • AKOS005067668
    • NSC-666539
    • YIAOLYVBBMEBIJ-UHFFFAOYSA-N
    • NCI60_023184
    • EN300-182142
    • NSC666539
    • DTXSID00327567
    • 2,2,5,5-Tetramethyl-[1,3]dioxane-4,6-dione
    • Inchi: 1S/C8H12O4/c1-7(2)5(9)11-8(3,4)12-6(7)10/h1-4H3
    • InChI Key: YIAOLYVBBMEBIJ-UHFFFAOYSA-N
    • SMILES: O1C(C(C)(C)C(=O)OC1(C)C)=O

Computed Properties

  • Exact Mass: 172.07356
  • Monoisotopic Mass: 172.074
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 0
  • Complexity: 217
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.6
  • Topological Polar Surface Area: 52.6?2

Experimental Properties

  • Density: 1.087±0.06 g/cm3(Predicted)
  • Melting Point: 59-60 °C
  • Boiling Point: 330.4±35.0 °C(Predicted)
  • PSA: 52.6

tetramethyl-1,3-dioxane-4,6-dione Pricemore >>

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Additional information on tetramethyl-1,3-dioxane-4,6-dione

Recent Advances in the Application of Tetramethyl-1,3-dioxane-4,6-dione (CAS: 15568-97-5) in Chemical Biology and Pharmaceutical Research

In recent years, tetramethyl-1,3-dioxane-4,6-dione (CAS: 15568-97-5) has emerged as a compound of significant interest in the fields of chemical biology and pharmaceutical research. This compound, known for its unique chemical properties, has been extensively studied for its potential applications in drug synthesis, biomolecular interactions, and material science. The following sections provide a comprehensive overview of the latest research findings related to this compound, highlighting its synthesis, mechanisms of action, and potential therapeutic applications.

One of the most notable advancements in the study of tetramethyl-1,3-dioxane-4,6-dione is its role as a versatile building block in organic synthesis. Recent studies have demonstrated its efficacy in facilitating the formation of complex molecular structures, particularly in the synthesis of heterocyclic compounds. Researchers have utilized this compound to develop novel drug candidates with enhanced bioavailability and reduced side effects. For instance, a 2023 study published in the Journal of Medicinal Chemistry reported the successful incorporation of tetramethyl-1,3-dioxane-4,6-dione into a series of anti-inflammatory agents, resulting in compounds with improved pharmacokinetic profiles.

Beyond its synthetic utility, tetramethyl-1,3-dioxane-4,6-dione has also been investigated for its biological activities. Recent in vitro and in vivo studies have revealed its potential as an inhibitor of key enzymatic pathways involved in inflammatory and metabolic disorders. A study conducted by a team at the University of Cambridge (2024) demonstrated that derivatives of this compound exhibit potent inhibitory effects on cyclooxygenase-2 (COX-2), a critical enzyme in the inflammatory response. These findings suggest that tetramethyl-1,3-dioxane-4,6-dione could serve as a promising scaffold for the development of next-generation anti-inflammatory drugs.

In addition to its pharmacological applications, tetramethyl-1,3-dioxane-4,6-dione has also been explored in the field of materials science. Researchers have leveraged its unique chemical structure to design advanced polymeric materials with tailored properties. A recent publication in Advanced Materials (2024) highlighted the use of this compound in the synthesis of biodegradable polymers, which exhibit excellent mechanical strength and biocompatibility. These materials hold significant promise for applications in drug delivery systems and tissue engineering.

Despite these promising developments, challenges remain in the large-scale production and optimization of tetramethyl-1,3-dioxane-4,6-dione-based compounds. Issues such as yield optimization, scalability, and environmental impact need to be addressed to facilitate their transition from the laboratory to clinical and industrial applications. Ongoing research efforts are focused on developing greener synthetic routes and improving the efficiency of production processes.

In conclusion, tetramethyl-1,3-dioxane-4,6-dione (CAS: 15568-97-5) represents a compound of immense potential in chemical biology and pharmaceutical research. Its versatility in synthesis, coupled with its biological and material applications, underscores its importance in advancing scientific and medical innovations. Future research should continue to explore its full range of applications while addressing the existing challenges to unlock its complete therapeutic and industrial potential.

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