Cas no 155306-71-1 (Coumarin 545T)
Coumarin 545T Chemical and Physical Properties
Names and Identifiers
-
- C545T
- 10-(2-Benzothiazolyl)-2,3,6,7-tetrahydro-1,1,7,7-tetramethyl-1H,5H,11H-(1)benzopyropyrano(6,7-8-I,j)quinolizin-11-one
- 10-(2-BENZOTHIAZOLYL)-2 3 6 7-TETRAHYDR&
- 10-(2-Benzothiazolyl)-2,3,6,7-tetrahydro-1,1,7,7,-tetramethyll-1H,5H,11H-1benzopyrano6,7,8-ijquinolizin-11-one
- (BENZOTHIAZOLYL)-TETRAHYDRO-TETRAMETHYL-BENZOPYROPYRANO QUINOLIZIN-11-ONE
- 10-(2-Benzothiazolyl)-1,1,7,7-tetramethyl-2,3,6,7-
- Coumarin545T
- BenzothiazolyltetrahydrotetramethylHHbenzopyranoijquinolizinone
- 1H,5H,11H-[1]Benzopyrano[6,7,8-ij]quinolizin-11-one,10-(2-benzothiazolyl)-2,3,6,7-tetrahydro-1,1,7,7-tetramethyl-
- 10-(2-BENZOTHIAZOLYL)-2,3,6,7-TETRAHYDRO-1,1,7,7-TETRAMETHYL-1H,5H,11H-(1)-BENZOPYROPYRANO(6,7-8-I,J)QUINOLIZIN-11-ONE
- X4214
- 10-(2-Benzothiazolyl)-2,3,6,7-tetrahydro-1,1,7,7-tetramethyl-1H,5H,11H-[1]benzopyrano[6,7,8-ij]quinolizin-11-one
- C545T, 2-Phenyl-9,10-di(naphthalen-2-yl)-anthracene
- C545T , 10-(2-Benzothiazolyl)-2,3,6,7-. Molecular ForMula
- 2,3,6,7-Tetrahydro-1,1,7,7,-tetramethyl-1H, 5H,11H-10-(2-benzothiazolyl)quinolizino[9,9a,1gh]coumarin
- Coumarin 545T
- C545T;X4214;Coumarin 545T
- 10-(2-Benzothiazolyl
- (ppy)2Ir(acac)
- MSDMPJCOOXURQD-UHFFFAOYSA-N
- BCP18976
- C 545T
- B4257
- 10-(2-benzothiazolyl)-2 3 6 7
- 10-(1,3-Benzothiazol-2-yl)-1,1,7,7-tetramethyl-2,3,6,7-tetrahydro- 1H,5H,11H-pyrano[3,2-g]pyrido[3,2,1- hi]quinoline
- 10-(Benzo[d]thiazol-2-yl)-1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H,5H,11H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11-one
- SCHEMBL871160
- 155306-71-1
- FT-0653579
- 3-NITRO-O-DIBROMOMETHYLBENZENE
- 5-(1,3-BENZOTHIAZOL-2-YL)-10,10,16,16-TETRAMETHYL-3-OXA-13-AZATETRACYCLO[7.7.1.0(2),?.0(1)(3),(1)?]HEPTADECA-1,5,7,9(17)-TETRAEN-4-ONE
- AKOS005145795
- 1H,5H,11H-[1]Benzopyrano[6,7,8-ij]quinolizin-11-one, 10-(2-benzothiazolyl)-2,3,6,7-tetrahydro-1,1,7,7-tetramethyl-
- 10-(2-benzothiazolyl)-1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1h,5h,11h-[1]benzopyrano[6,7,8-ij]quinolizin-11-one
- Q27122962
- 10-(2-BENZOTHIAZOLYL)-2 3 6 7-TETRAHYDR&;C545T
- MFCD03427187
- 2,3,6,7-Tetrahydro-1,1,7,7,-tetramethyl-1H,5H,11H-10-(2-
- C-545T
- 10-(2-Benzothiazolyl)-2,3,6,7-tetrahydro-1,1,7,7-tetramethyl-1H,5H,11H-(1)benzopyropyrano(6,7-8-I,j)
- DTXSID60408462
- 2,3,6,7-Tetrahydro-1,1,7,7,-tetramethyl-1H,5H,11H-10-(2-benzothiazolyl)quinol
- A847603
- 2,3,6,7-Tetrahydro-1,1,7,7-tetramethyl-1H,5H,11H-10-(2-benzothiazolyl)quinolizino[9,9a,1gh]coumarin
- CHEBI:51896
- benzothiazolyl)quinolizino[9,9a,1gh]coumarin
- 5-(1,3-Benzothiazol-2-yl)-10,10,16,16-tetramethyl-3-oxa-13-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1,5,7,9(17)-tetraen-4-one
- 10-(2-Benzothiazolyl)-2,3,6,7-tetrahydro- 1,1,7,7-tetramethyl-1H,5H,11H-(1)benzopyropyrano (6,7-8-I,j)quinolizin -11-one
- AS-75003
- 10-(1,3-benzothiazol-2-yl)-1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H,5H,11H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11-one
- A12100
- Bis[2-(2-pyridinyl-N)phenyl-C](acetylacetonato)iridium(III)
-
- MDL： MFCD03427187
- Inchi： 1S/C26H26N2O2S/c1-25(2)9-11-28-12-10-26(3,4)20-21(28)17(25)14-15-13-16(24(29)30-22(15)20)23-27-18-7-5-6-8-19(18)31-23/h5-8,13-14H,9-12H2,1-4H3
- InChI Key： MSDMPJCOOXURQD-UHFFFAOYSA-N
- SMILES： S1C2C=CC=CC=2N=C1C1C(=O)OC2C(C=1)=CC1=C3C=2C(C)(C)CCN3CCC1(C)C
Computed Properties
- Exact Mass: 430.17100
- Monoisotopic Mass: 430.17149925g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 31
- Rotatable Bond Count: 1
- Complexity: 792
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- XLogP3: 6.7
- Topological Polar Surface Area: 70.7
Experimental Properties
- Color/Form: Orange crystal
- Density: 1.3±0.1 g/cm3
- Melting Point: 225.0 to 229.0 deg-C
- Boiling Point: 615.3±65.0 °C at 760 mmHg
- Flash Point: 325.9±34.3 °C
- PSA: 74.58000
- LogP: 6.30370
- Solubility: Not determined
Coumarin 545T Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- WGK Germany：3
- Safety Instruction： S22-S24/25
- Safety Term：S22;S24/25
- Storage Condition：Store at 4°C,-4At ℃Store…Better
Coumarin 545T Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd. | B4257-200MG |
Coumarin 545T |
155306-71-1 | >98.0%(N) | 200mg |
￥1390.00 | 2024-04-17 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | C130046-250mg |
Coumarin 545T |
155306-71-1 | 98% | 250mg |
￥1199.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | C130046-1g |
Coumarin 545T |
155306-71-1 | 98% | 1g |
￥3699.90 | 2023-09-03 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | BB9522-100mg |
Coumarin 545T |
155306-71-1 | ≥99% | 100mg |
￥1850元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | BB9522-1g |
Coumarin 545T |
155306-71-1 | ≥99% | 1g |
￥5500元 | 2023-09-15 | |
| TRC | C755540-2.5mg |
Coumarin 545T |
155306-71-1 | 2.5mg |
$ 50.00 | 2022-01-10 | ||
| TRC | C755540-5mg |
Coumarin 545T |
155306-71-1 | 5mg |
$184.00 | 2023-05-18 | ||
| TRC | C755540-25mg |
Coumarin 545T |
155306-71-1 | 25mg |
$839.00 | 2023-05-18 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | B838216-25g |
(BENZOTHIAZOLYL)-TETRAHYDRO-TETRAMETHYL-BENZOPYROPYRANO QUINOLIZIN-11-ONE |
155306-71-1 | 90 % | 25g |
376.00 | 2021-05-17 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | B871797-1g |
(BENZOTHIAZOLYL)-TETRAHYDRO-TETRAMETHYL-BENZOPYROPYRANO QUINOLIZIN-11-ONE |
155306-71-1 | 98% | 1g |
2,587.00 | 2021-05-17 |
Coumarin 545T Related Literature
-
Ronggang Shangguan,Guangyuan Mu,Lei Wang,Shaoqing Zhuang,Wangbo,Chin H. Chen J. Mater. Chem. C 2015 3 6916
Additional information on Coumarin 545T
Recent Advances in the Application of Coumarin 545T (155306-71-1) in Chemical Biology and Pharmaceutical Research
Coumarin derivatives have long been recognized for their versatile applications in chemical biology and pharmaceutical research. Among these, Coumarin 545T (CAS: 155306-71-1) has emerged as a particularly promising compound due to its unique photophysical properties and potential therapeutic applications. This research briefing aims to provide an overview of the latest advancements in the study of Coumarin 545T, focusing on its synthesis, characterization, and applications in drug discovery and biomedical imaging.
Recent studies have highlighted the exceptional fluorescence properties of Coumarin 545T, making it a valuable tool for bioimaging and diagnostic applications. Researchers have successfully utilized this compound as a fluorescent probe for tracking cellular processes, such as protein-protein interactions and intracellular signaling pathways. The high quantum yield and photostability of Coumarin 545T enable prolonged imaging sessions with minimal photobleaching, a critical advantage for live-cell imaging studies.
In the realm of drug discovery, Coumarin 545T has shown potential as a scaffold for developing novel therapeutic agents. Structural modifications of the coumarin core have yielded derivatives with enhanced bioavailability and target specificity. Notably, recent computational studies have explored the binding affinities of Coumarin 545T derivatives with various biological targets, including kinases and G-protein-coupled receptors, suggesting promising avenues for future drug development.
The synthesis and optimization of Coumarin 545T have also seen significant progress. Novel synthetic routes have been developed to improve yield and purity while reducing environmental impact. Green chemistry approaches, such as microwave-assisted synthesis and solvent-free reactions, have been successfully applied to the production of Coumarin 545T, aligning with the growing emphasis on sustainable pharmaceutical manufacturing.
Pharmacological evaluations of Coumarin 545T derivatives have revealed interesting biological activities, including anti-inflammatory, antioxidant, and antimicrobial properties. These findings have spurred further investigation into the compound's mechanism of action and potential clinical applications. Recent in vivo studies have demonstrated the compound's favorable pharmacokinetic profile and low toxicity, supporting its potential translation into therapeutic use.
Looking forward, researchers are exploring the integration of Coumarin 545T with emerging technologies such as nanotechnology and targeted drug delivery systems. Preliminary studies have shown that nanoparticle formulations incorporating Coumarin 545T can enhance drug solubility and tissue specificity while maintaining the compound's beneficial properties. These developments open new possibilities for precision medicine applications.
In conclusion, Coumarin 545T (155306-71-1) continues to be a compound of significant interest in chemical biology and pharmaceutical research. Its unique combination of photophysical properties and biological activities makes it a versatile tool for both basic research and therapeutic development. As synthetic methodologies advance and our understanding of its biological interactions deepens, we anticipate seeing more innovative applications of this compound in the coming years.
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