Coumarins and derivatives
Coumarins and their derivatives are a diverse class of organic compounds characterized by the benzopyran ring system, which includes a benzene ring fused to a heterocyclic pyrrole. These compounds exhibit a wide range of biological activities, including anticoagulant, anti-inflammatory, and antimicrobial properties. Structurally, coumarins can be identified by their characteristic keto-enol tautomerism, where the enolic form (C=O) and the lactone form (C-O) interconvert under physiological conditions.
The derivatives of coumarins are typically modified through substitutions on the benzene ring or within the pyrrole part. These modifications can significantly alter the chemical properties and biological activities of these compounds, making them valuable in pharmaceuticals, agrochemicals, and cosmetic industries. For instance, dicoumarol, a derivative of coumarin, is known for its anticoagulant effects and has been used as a model compound to study vitamin K antagonists.
In the research and development field, coumarins and their derivatives are often synthesized using various chemical reactions such as Friedel-Crafts acylation, alkylation, or reduction. These processes enable the creation of new compounds with specific functionalities tailored for diverse applications in medicine, agriculture, and personal care products.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
![]() |
7-(Diethylamino)-4-(hydroxymethyl)coumarin | 54711-38-5 | C14H17NO3 |
![]() |
2H-1-Benzopyran-3-carboxaldehyde, 7-(diethylamino)-2-oxo- | 57597-64-5 | C14H15NO3 |
![]() |
7H-1,3-Dioxolo[4,5-f][1]benzopyran-7-one,4-[(3,3-dimethyloxiranyl)methoxy]- | 57419-59-7 | C15H14O6 |
![]() |
2H-1-Benzopyran-2-one, 3,6-dimethyl- | 57295-24-6 | C11H10O2 |
![]() |
Methyl (7-Methoxy-2-oxo-2H-chromen-4-yl)acetate | 62935-73-3 | C13H12O5 |
![]() |
3-Acetamidocoumarin | 779-30-6 | C11H9NO3 |
![]() |
4-Methylumbelliferyl Stearate | 79408-85-8 | C28H42O4 |
![]() |
4-Ethoxycoumarin | 35817-27-7 | C11H10O3 |
![]() |
2H-1-Benzopyran-2-one,4-methyl-7-(2-propen-1-yloxy)- | 3993-57-5 | C13H12O3 |
![]() |
2H-1-Benzopyran-2-one,7-(2-oxiranylmethoxy)- | 36651-62-4 | C12H10O4 |
Related Literature
-
Shaun D. Wong,Edward I. Solomon Dalton Trans., 2014,43, 17567-17577
-
Fereshteh Bayat Environ. Sci.: Nano, 2021,8, 367-389
-
Chung-Sung Yang,Mong-Shian Shih,Fang-Yi Chang New J. Chem., 2006,30, 729-735
-
Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
Recommended suppliers
-
TAIXING JOXIN BIO-TEC CO.,LTD.Factory Trade Brand reagentsCompany nature: Private enterprises
-
SunaTech Inc.Factory Trade Brand reagentsCompany nature: Private enterprises
-
Enjia Trading Co., LtdFactory Trade Brand reagentsCompany nature: Private enterprises
-
Hubei Cuiyuan Biotechnology Co.,LtdFactory Trade Brand reagentsCompany nature: Private enterprises
-
Nanjing jingzhu bio-technology Co., Ltd.Factory Trade Brand reagentsCompany nature: Private enterprises
Recommended products









