Cas no 153203-80-6 (3,5-dichloro-4-formylbenzoic acid)

3,5-Dichloro-4-formylbenzoic acid is a versatile aromatic compound featuring both aldehyde and carboxylic acid functional groups, along with two chlorine substituents at the 3- and 5-positions. This structure makes it a valuable intermediate in organic synthesis, particularly for constructing complex molecules in pharmaceuticals, agrochemicals, and specialty chemicals. The presence of reactive functional groups allows for further derivatization, enabling applications in cross-coupling reactions, condensation reactions, and heterocycle formation. Its high purity and stability under standard conditions ensure consistent performance in research and industrial processes. The compound is particularly useful in the development of bioactive compounds and advanced materials due to its balanced reactivity and structural rigidity.
3,5-dichloro-4-formylbenzoic acid structure
153203-80-6 structure
Product Name:3,5-dichloro-4-formylbenzoic acid
CAS No:153203-80-6
MF:C8H4Cl2O3
MW:219.021560668945
MDL:MFCD24483956
CID:2950396
PubChem ID:19788159
Update Time:2025-10-28

3,5-dichloro-4-formylbenzoic acid Chemical and Physical Properties

Names and Identifiers

    • 3,5-dichloro-4-formylbenzoic acid
    • 3,5-二氯-4-醛基苯甲酸
    • DS-10240
    • KNZHVHRJCNWQKI-UHFFFAOYSA-N
    • SY109244
    • 4-formyl-3,5-dichloro benzoic acid
    • 153203-80-6
    • AKOS027252197
    • SB17776
    • MFCD24483956
    • SCHEMBL3069036
    • AC-30605
    • CS-0054520
    • DB-218917
    • 3,5-dichloro-4-formylbenzoicacid
    • P13953
    • 4-formyl-3,5-dichlorobenzoic acid
    • C8H4Cl2O3
    • MDL: MFCD24483956
    • Inchi: 1S/C8H4Cl2O3/c9-6-1-4(8(12)13)2-7(10)5(6)3-11/h1-3H,(H,12,13)
    • InChI Key: KNZHVHRJCNWQKI-UHFFFAOYSA-N
    • SMILES: ClC1C=C(C(=O)O)C=C(C=1C=O)Cl

Computed Properties

  • Exact Mass: 217.9537494g/mol
  • Monoisotopic Mass: 217.9537494g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 2
  • Complexity: 207
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.2
  • Topological Polar Surface Area: 54.4?2

Experimental Properties

  • Boiling Point: 366.7±42.0°C at 760 mmHg

3,5-dichloro-4-formylbenzoic acid Security Information

3,5-dichloro-4-formylbenzoic acid Pricemore >>

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Additional information on 3,5-dichloro-4-formylbenzoic acid

3,5-Dichloro-4-formylbenzoic Acid (CAS No. 153203-80-6): Properties, Applications, and Market Insights

3,5-Dichloro-4-formylbenzoic acid (CAS No. 153203-80-6) is a specialized organic compound with a unique molecular structure that combines a benzoic acid core with formyl and dichloro functional groups. This compound has garnered significant attention in the chemical and pharmaceutical industries due to its versatile reactivity and potential applications. With the growing demand for fine chemicals and intermediates in drug development, 3,5-dichloro-4-formylbenzoic acid has emerged as a valuable building block for synthesizing more complex molecules.

The molecular formula of 3,5-dichloro-4-formylbenzoic acid is C8H4Cl2O3, and it features a molecular weight of 219.02 g/mol. The presence of both electron-withdrawing chloro groups and the reactive formyl group makes this compound particularly useful in organic synthesis. Researchers often explore its potential in creating derivatives for various applications, including materials science and medicinal chemistry. The compound's solubility in polar organic solvents like dimethyl sulfoxide (DMSO) and methanol further enhances its utility in laboratory settings.

One of the most prominent applications of 3,5-dichloro-4-formylbenzoic acid is in the pharmaceutical industry, where it serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). The compound's ability to undergo various chemical transformations, such as condensation reactions and nucleophilic substitutions, makes it a valuable tool for drug discovery. Recent studies have highlighted its role in developing novel anti-inflammatory and antimicrobial agents, aligning with the current global focus on combating antibiotic resistance and chronic diseases.

In addition to pharmaceutical applications, 3,5-dichloro-4-formylbenzoic acid finds use in materials science. Its incorporation into polymers and coatings can impart unique properties such as enhanced thermal stability and chemical resistance. The compound's aromatic structure and functional groups make it a promising candidate for developing advanced materials for electronics and nanotechnology applications. Researchers are also exploring its potential in creating metal-organic frameworks (MOFs), which have gained traction in gas storage and separation technologies.

The market for 3,5-dichloro-4-formylbenzoic acid is influenced by several factors, including the growing demand for specialty chemicals and the expansion of the pharmaceutical sector. With increasing investments in research and development, the compound's applications are expected to diversify further. Manufacturers and suppliers are focusing on optimizing production processes to meet the rising demand while ensuring high purity and consistency. The compound's CAS No. 153203-80-6 serves as a unique identifier in global chemical databases, facilitating its trade and regulatory compliance.

Environmental and safety considerations are paramount when handling 3,5-dichloro-4-formylbenzoic acid. While the compound is not classified as hazardous under standard regulations, proper laboratory practices, including the use of personal protective equipment (PPE) and adequate ventilation, are recommended. Researchers and industrial users must adhere to guidelines for safe storage and disposal to minimize environmental impact. The compound's stability under normal conditions makes it a relatively safe choice for various applications, provided standard precautions are followed.

Recent advancements in synthetic chemistry have opened new avenues for utilizing 3,5-dichloro-4-formylbenzoic acid. For instance, its role in click chemistry and multicomponent reactions has been explored, offering efficient pathways to complex molecules. The compound's compatibility with green chemistry principles, such as solvent-free reactions and catalytic processes, aligns with the industry's shift toward sustainable practices. These developments underscore the compound's relevance in modern chemical research and its potential to address contemporary challenges in science and technology.

In conclusion, 3,5-dichloro-4-formylbenzoic acid (CAS No. 153203-80-6) is a multifaceted compound with significant applications in pharmaceuticals, materials science, and beyond. Its unique chemical properties and reactivity make it a valuable asset in research and industrial settings. As the demand for innovative chemical solutions grows, this compound is poised to play a pivotal role in advancing scientific and technological frontiers. Stakeholders across the chemical and pharmaceutical sectors are encouraged to explore its potential further, leveraging its versatility to drive innovation and address global challenges.

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