Cas no 50-84-0 (2,4-Dichlorobenzoic acid)

2,4-Dichlorobenzoic acid is a chlorinated aromatic carboxylic acid with the molecular formula C?H?Cl?O?. It is a white to off-white crystalline solid, widely used as an intermediate in organic synthesis, particularly in the production of agrochemicals, pharmaceuticals, and dyes. The compound's key advantages include its stability under standard conditions, high purity, and reactivity as a building block for further functionalization. Its dichloro-substituted aromatic ring enhances electrophilic properties, making it valuable for cross-coupling reactions and derivatization. The acid group allows for further modifications, such as esterification or amidation. It is soluble in organic solvents like ethanol and acetone but has limited water solubility, ensuring compatibility with diverse synthetic applications.
2,4-Dichlorobenzoic acid structure
2,4-Dichlorobenzoic acid structure
Product Name:2,4-Dichlorobenzoic acid
CAS No:50-84-0
MF:C7H4Cl2O2
MW:191.01146030426
MDL:MFCD00002414
CID:33502
PubChem ID:5787
Update Time:2025-11-01

2,4-Dichlorobenzoic acid Chemical and Physical Properties

Names and Identifiers

    • 2,4-Dichlorobenzoic acid
    • 2,4-DCBA
    • 2,4-Dichlolrobenzoic Acid
    • 2,4-Dichlorbenzoic acid
    • 2.4-Dichlorobenzoicacid
    • Benzoic acid, 2,4-dichloro-
    • 2,4-Dichlorobenzoesyre
    • 2,4 dichlorobenzoic acid
    • 2,4-Dichloro-benzoic acid
    • ATCRIUVQKHMXSH-UHFFFAOYSA-N
    • 0SR0320D45
    • 2,4-Dichlorobenzoicacid
    • PubChem21313
    • WLN: QVR BG DG
    • DSSTox_CID_4977
    • bmse000672
    • C06670
    • DSSTox_RID_77606
    • DSSTox_GSID_24977
    • KSC269I7L
    • NSC578
    • EN300-18039
    • Q27104142
    • AKOS000119754
    • NSC-578
    • 50-84-0
    • 2,4-Dichlorobenzoic acid, PESTANAL(R), analytical standard
    • NCGC00258310-01
    • MFCD00002414
    • NCGC00091214-02
    • AG-617/02198062
    • 2,4-Dichlorobenzoic acid, 98%
    • NCGC00091214-03
    • BB 0240623
    • A23852
    • AB01333124-02
    • Furosemide Imp. E (EP):2,4-Dichlorobenzoic acid
    • W-105928
    • NCGC00091214-01
    • STR01599
    • FT-0610044
    • DTXSID0024977
    • Tox21_200756
    • 2,4-dichlorbenzoesyre
    • AM20050123
    • BRN 1868192
    • FUROSEMIDE IMPURITY E [EP IMPURITY]
    • 2,4-Dichlorobenzoic Acid; Furosemide Imp. E (EP); 2,4-Dichlorobenzyl Alcohol Impurity E; Furosemide Impurity E
    • D0337
    • SY007062
    • EINECS 200-067-8
    • PS-4049
    • SCHEMBL111279
    • DICHLOROBENZOIC ACID, 2,4-
    • F2191-0069
    • Z57127531
    • UNII-0SR0320D45
    • PD163264
    • AI3-14873
    • DTXCID104977
    • STK297837
    • NSC 578
    • CHEBI:30748
    • CHEMBL1492029
    • LS-146
    • D77744
    • AC-22899
    • CS-W013226
    • CCRIS 9472
    • CAS-50-84-0
    • InChI=1/C7H4Cl2O2/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3H,(H,10,11
    • NS00010527
    • "2
    • "InChI=1S/C7H4Cl2O2/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3H
    • 2,4-Dichlorobenzoic acid,99%
    • 4-09-00-00998 (Beilstein Handbook Reference)
    • FUROSEMIDE IMPURITY E (EP IMPURITY)
    • MDL: MFCD00002414
    • Inchi: 1S/C7H4Cl2O2/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3H,(H,10,11)
    • InChI Key: ATCRIUVQKHMXSH-UHFFFAOYSA-N
    • SMILES: ClC1C=C(C=CC=1C(=O)O)Cl
    • BRN: 1868192

Computed Properties

  • Exact Mass: 189.95900
  • Monoisotopic Mass: 189.958835
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 161
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 2.8
  • Topological Polar Surface Area: 37.3

Experimental Properties

  • Color/Form: Pale yellow powder
  • Density: 1.517g/cm3
  • Melting Point: 157-160?°C(lit.)
  • Boiling Point: 200 °C
  • Flash Point: 141°C
  • Refractive Index: 1.4590 (estimate)
  • PH: 2.8 (0.36g/l, H2O, 15℃)
  • Solubility: ethanol: soluble1g/10 mL, clear, colorless
  • Water Partition Coefficient: 0.36 g/L (15 oC)
  • Stability/Shelf Life: Stable. Incompatible with strong oxidizing agents.
  • PSA: 37.30000
  • LogP: 2.69160
  • Vapor Pressure: 0.000275mmHg at 25°C
  • Solubility: Soluble in ethanol, diethyl ether, benzene, acetone, chloroform, 5% caustic soda solution, insoluble in water and heptane.

2,4-Dichlorobenzoic acid Security Information

  • Symbol: GHS07
  • Prompt:warning
  • Signal Word:Warning
  • Hazard Statement: H302,H315,H319,H335
  • Warning Statement: P261,P305+P351+P338
  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • Hazard Category Code: 22-36/37/38
  • Safety Instruction: S26-S36-S37/39-S22
  • RTECS:DG6650000
  • Hazardous Material Identification: Xn
  • TSCA:Yes
  • Storage Condition:Sealed in dry,Room Temperature
  • Safety Term:S22;S26;S37/39
  • Risk Phrases:R36/37/38

2,4-Dichlorobenzoic acid Customs Data

  • HS CODE:2916399090
  • Customs Data:

    China Customs Code:

    2916399090

    Overview:

    2916399090 Other aromatic monocarboxylic acids. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, Acrylic acid\Acrylates or esters shall be packaged clearly

    Summary:

    2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

2,4-Dichlorobenzoic acid Pricemore >>

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2,4-Dichlorobenzoic acid Production Method

2,4-Dichlorobenzoic acid Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:50-84-0)2,4-二氯苯甲酸
Order Number:LE26721147;LE14564;LE6510
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:58
Price ($):discuss personally
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:50-84-0)2,4-Dichlorobenzoic acid
Order Number:sfd20686
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:38
Price ($):discuss personally

2,4-Dichlorobenzoic acid Spectrogram

GC-MS
GC-MS
13C NMR
13C NMR
1H NMR 300 MHz DMSO
1H NMR

Additional information on 2,4-Dichlorobenzoic acid

Introduction to 2,4-Dichlorobenzoic acid (CAS No: 50-84-0)

2,4-Dichlorobenzoic acid, with the chemical formula C?H?Cl?O? and CAS number 50-84-0, is a significant compound in the field of organic chemistry and pharmaceutical research. This benzoic acid derivative features two chlorine substituents at the 2nd and 4th positions of the benzene ring, which confer unique chemical properties and reactivity. Its molecular structure makes it a valuable intermediate in the synthesis of various pharmaceuticals, agrochemicals, and specialty chemicals.

The compound is widely recognized for its role in medicinal chemistry due to its ability to serve as a precursor for more complex molecules. Its structural framework allows for further functionalization, making it a versatile building block in drug discovery and development. Recent advancements in synthetic methodologies have enhanced the efficiency of producing 2,4-Dichlorobenzoic acid, enabling researchers to explore its potential in diverse applications.

In recent years, 2,4-Dichlorobenzoic acid has garnered attention for its applications in the development of novel therapeutic agents. Studies have highlighted its utility in synthesizing compounds with anti-inflammatory, antimicrobial, and anticancer properties. The chlorine atoms in its structure facilitate various chemical transformations, including nucleophilic aromatic substitution and metal-catalyzed coupling reactions, which are crucial for constructing biologically active molecules.

One of the most compelling aspects of 2,4-Dichlorobenzoic acid is its role in the synthesis of benzoic acid derivatives that exhibit potent biological activity. For instance, researchers have utilized this compound to develop inhibitors targeting specific enzymes involved in metabolic pathways. These inhibitors have shown promise in preclinical studies for treating conditions such as diabetes and hyperlipidemia. The ability to modify the substituents on the benzene ring allows for fine-tuning of pharmacological properties, leading to more effective and selective drugs.

The pharmaceutical industry has also explored the use of 2,4-Dichlorobenzoic acid in creating advanced materials for drug delivery systems. Its incorporation into polymeric matrices enhances the stability and bioavailability of active pharmaceutical ingredients (APIs). This approach has been particularly useful for formulations requiring controlled release profiles, ensuring sustained therapeutic effects.

Beyond pharmaceuticals, 2,4-Dichlorobenzoic acid finds applications in agrochemicals as a key intermediate in the production of herbicides and fungicides. Its structural features contribute to the efficacy of these compounds by improving their binding affinity to target enzymes in plants. This has led to the development of more sustainable agricultural practices by enhancing crop protection strategies.

The environmental impact of using 2,4-Dichlorobenzoic acid as an intermediate has also been studied extensively. Researchers are focusing on developing greener synthetic routes to minimize waste and reduce environmental footprint. Innovations such as catalytic hydrogenation and enzymatic transformations are being explored to achieve this goal. These efforts align with global initiatives aimed at promoting sustainable chemistry practices.

In conclusion, 2,4-Dichlorobenzoic acid (CAS No: 50-84-0) is a multifaceted compound with broad applications across multiple industries. Its unique chemical properties make it an indispensable tool in pharmaceutical research, enabling the development of innovative therapies. Additionally, its role in agrochemicals and specialty chemicals underscores its versatility. As scientific understanding progresses, new applications for this compound are likely to emerge, further solidifying its importance in modern chemistry.

Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:50-84-0)2,4-二氯苯甲酸
LE26721147;LE14564;LE6510
Purity:99%/99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry/Inquiry
Email
Suzhou Senfeida Chemical Co., Ltd
(CAS:50-84-0)2,4-Dichlorobenzoic acid
sfd20686
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email