Cas no 1504981-94-5 (methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate)
Methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate is a fluorinated pyrimidine derivative with significant utility in pharmaceutical and agrochemical synthesis. Its key structural features—the dichloro and fluoro substituents—enhance reactivity, making it a versatile intermediate for nucleophilic substitution reactions. The ester group at the 2-position further facilitates derivatization, enabling the introduction of diverse functional groups. This compound is particularly valued for its role in constructing heterocyclic frameworks, contributing to the development of bioactive molecules. High purity and stability under standard storage conditions ensure consistent performance in synthetic applications. Its compatibility with common reagents and solvents underscores its practicality in industrial and research settings.
1504981-94-5 structure
Product Name:methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate
CAS No:1504981-94-5
MF:C6H3Cl2FN2O2
MW:225.00462269783
MDL:MFCD23931505
CID:4602795
PubChem ID:80550148
Update Time:2025-05-28
methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate Chemical and Physical Properties
Names and Identifiers
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- methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate
-
- MDL: MFCD23931505
- Inchi: 1S/C6H3Cl2FN2O2/c1-13-6(12)5-10-3(7)2(9)4(8)11-5/h1H3
- InChI Key: BVDDAIMYERQXGF-UHFFFAOYSA-N
- SMILES: C1(C(OC)=O)=NC(Cl)=C(F)C(Cl)=N1
Computed Properties
- Exact Mass: 223.9555609g/mol
- Monoisotopic Mass: 223.9555609g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 13
- Rotatable Bond Count: 2
- Complexity: 195
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.4
- Topological Polar Surface Area: 52.1?2
methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM470567-1g |
methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate |
1504981-94-5 | 95%+ | 1g |
$1305 | 2023-02-02 | |
| SHANG HAI BI DE YI YAO KE JI GU FEN Co., Ltd. | BD00996758-1g |
Methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate |
1504981-94-5 | 95% | 1g |
¥5971.0 | 2023-04-01 | |
| Enamine | EN300-257283-0.05g |
methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate |
1504981-94-5 | 95% | 0.05g |
$222.0 | 2024-06-18 | |
| Enamine | EN300-257283-0.1g |
methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate |
1504981-94-5 | 95% | 0.1g |
$331.0 | 2024-06-18 | |
| Enamine | EN300-257283-0.25g |
methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate |
1504981-94-5 | 95% | 0.25g |
$474.0 | 2024-06-18 | |
| Enamine | EN300-257283-0.5g |
methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate |
1504981-94-5 | 95% | 0.5g |
$746.0 | 2024-06-18 | |
| Enamine | EN300-257283-1.0g |
methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate |
1504981-94-5 | 95% | 1.0g |
$956.0 | 2024-06-18 | |
| Enamine | EN300-257283-2.5g |
methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate |
1504981-94-5 | 95% | 2.5g |
$1874.0 | 2024-06-18 | |
| Enamine | EN300-257283-5.0g |
methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate |
1504981-94-5 | 95% | 5.0g |
$2774.0 | 2024-06-18 | |
| Enamine | EN300-257283-10.0g |
methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate |
1504981-94-5 | 95% | 10.0g |
$4114.0 | 2024-06-18 |
methyl 4,6-dichloro-5-fluoropyrimidine-2-carboxylate Related Literature
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Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026
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Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
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Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
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