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• 4. Inclusion compounds of cis- and trans-3,3-bis(4-methylphenyl)cyclopropane-1,2-dicarboxylic acid hosts with ethanol guests. Crystal structures and selective inclusion modes
  Ingeborg Cs?regh,Olga Gallardo,Edwin Weber,Manfred Hecker,Andreas Wierig J. Chem. Soc. Perkin Trans. 2 1992 1939
• 5. Inclusion compounds of cis- and trans-3,3-bis(4-methylphenyl)cyclopropane-1,2-dicarboxylic acid hosts with ethanol guests. Crystal structures and selective inclusion modes
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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Cyclopropanecarboxylic acids
• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Cyclopropanecarboxylic acids and derivatives Cyclopropanecarboxylic acids

Cyclopropane-1,2-dicarboxylic Acid (CAS No. 1489-58-3): A Comprehensive Overview

Cyclopropane-1,2-dicarboxylic acid (CAS No. 1489-58-3) is a unique and versatile compound that has garnered significant attention in the fields of organic chemistry, materials science, and pharmaceutical research. This compound, also known as 1,2-cyclopropanedicarboxylic acid, is characterized by its cyclopropane ring structure with two carboxylic acid groups attached to adjacent carbon atoms. The unique structural features of this molecule make it an intriguing subject for both academic and industrial applications.

The chemical structure of Cyclopropane-1,2-dicarboxylic acid is represented by the formula C₅H₆O₄. Its molecular weight is 130.10 g/mol, and it exists as a white crystalline solid at room temperature. The compound is highly soluble in water and polar organic solvents, which makes it suitable for a wide range of chemical reactions and processes.

In recent years, the study of Cyclopropane-1,2-dicarboxylic acid has expanded significantly due to its potential applications in various fields. One of the most notable areas of research is its use in the synthesis of biodegradable polymers. The cyclopropane ring structure provides a rigid framework that can enhance the mechanical properties of polymers while maintaining biodegradability. This property is particularly valuable in the development of environmentally friendly materials for packaging, biomedical devices, and drug delivery systems.

Another area of interest is the use of Cyclopropane-1,2-dicarboxylic acid in pharmaceutical research. The compound's carboxylic acid groups can be functionalized to create derivatives with specific biological activities. For example, recent studies have explored the potential of these derivatives as anti-inflammatory agents and inhibitors of specific enzymes involved in disease pathways. The ability to tailor the chemical structure through functionalization opens up new possibilities for drug discovery and development.

The synthesis of Cyclopropane-1,2-dicarboxylic acid has been optimized using various methods, including catalytic cycloaddition reactions and ring-opening polymerization techniques. These methods have improved the yield and purity of the compound, making it more accessible for large-scale applications. Additionally, the development of efficient synthetic routes has reduced the environmental impact associated with its production, aligning with sustainable chemistry principles.

In the context of materials science, Cyclopropane-1,2-dicarboxylic acid has shown promise as a building block for advanced materials with unique properties. For instance, researchers have used this compound to create self-healing materials that can repair themselves when damaged. The cyclopropane ring's inherent strain energy contributes to the material's ability to undergo reversible cross-linking reactions, which is crucial for self-healing functionality.

The physical and chemical properties of Cyclopropane-1,2-dicarboxylic acid have also been extensively studied to understand its behavior under different conditions. For example, its thermal stability and solubility characteristics are important factors in determining its suitability for various applications. Recent research has focused on optimizing these properties through chemical modifications and processing techniques.

In conclusion, Cyclopropane-1,2-dicarboxylic acid (CAS No. 1489-58-3) is a multifaceted compound with a wide range of potential applications in organic chemistry, materials science, and pharmaceutical research. Its unique structural features and versatile chemical properties make it an attractive candidate for further investigation and development. As research continues to advance, it is likely that new and innovative uses for this compound will emerge, contributing to advancements in multiple scientific fields.

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• 13536-04-4(2-Butylcyclopropanecarboxylic acid)
• 89615-02-1(3-methylcyclopropane-1,2-dicarboxylic acid, Mixture of diastereomers)
• 10487-86-2((1R,2R)-2-Methylcyclopropanecarboxylic Acid)
• 15898-87-0(2-octylcyclopropanecarboxylic Acid)
• 697290-77-0(2-Heptylcyclopropanecarboxylic acid, trans-)
• 161271-43-8(Heptadecanoic acid, cyclopropyl-)
• 29667-48-9((1R,2S)-2-methylcyclopropanecarboxylic acid)
• 696-75-3(trans-cyclopropane-1,2-dicarboxylic acid)
• 14590-54-6((1S,2S)-Cyclopropane-1,2-dicarboxylic acid)