Cas no 14788-12-6 (3-(Dimethylamino)propanoic acid hydrochloride)

3-(Dimethylamino)propanoic acid hydrochloride is a quaternary ammonium compound with applications in organic synthesis and pharmaceutical research. Its hydrochloride salt form enhances stability and solubility, making it suitable for use in aqueous and polar solvent systems. The compound serves as a versatile intermediate in the preparation of betaine derivatives, surfactants, and bioactive molecules. Its dimethylamino group facilitates further functionalization, while the carboxylic acid moiety allows for conjugation or derivatization. The hydrochloride form ensures consistent handling and storage properties. This reagent is particularly valued for its role in synthesizing zwitterionic compounds and as a building block in medicinal chemistry.
3-(Dimethylamino)propanoic acid hydrochloride structure
14788-12-6 structure
Product Name:3-(Dimethylamino)propanoic acid hydrochloride
CAS No:14788-12-6
MF:C5H12ClNO2
MW:153.607280731201
MDL:MFCD02093464
CID:120638
PubChem ID:11586327
Update Time:2025-11-02

3-(Dimethylamino)propanoic acid hydrochloride Chemical and Physical Properties

Names and Identifiers

    • 3-(Dimethylamino)propanoic acid hydrochloride
    • 3-(Dimethylamino)propionic Acid Hydrochloride
    • 3-DIMETHYLAMINOPROPIONIC ACID HYDROCHLORIDE
    • b-Alanine, N,N-dimethyl-,hydrochloride (1:1)
    • N,N-Dimethyl-β-alanine Hydrochloride
    • β-(Dimethylamino)propanoic acid hydrochloride
    • N,N-DiMethyl-b-alanine HCl
    • 3-DimethylaminopropionicacidHCl
    • N,N-DIMETHYL-BETA-ALANINE HYDROCHLORIDE
    • Dimethylaminopropionicacidhydrochloride
    • 3-DIMETHYLAMINOPROPIONIC ACID HYDROCHLORIDE 98+%
    • 3-(Dimethylamino)propionic acid hydrochloride 97%
    • 3-(DIMETHYLAMINO)PROPANOIC ACID HCL
    • JTNKXYWGZCNBCH-UHFFFAOYSA-N
    • dimethyl-beta-alanine hydrochloride
    • 3-(Dimethylamino)propionic acid HCl
    • AM86616
    • 3-(dimethylamino)propionic acid
    • 3-(dimethylamino)propanoicacidhydrochloride
    • 3-Dimethylaminopropinoic Acid HCl
    • beta-Alanine, N,N-dimethyl-, hydrochloride (1:1)
    • N,N-Dimethyl-beta-alanine hydrochloride, AldrichCPR
    • BP-12329
    • 3-dimethylamino propionic acid hydrochloride
    • D2690
    • DTXSID10468970
    • SY031864
    • AKOS015845991
    • MFCD02093464
    • CS-W007826
    • FT-0649867
    • 3-(Dimethylamino)propionic acid hydrochloride, 97%
    • A846482
    • 3-(dimethylamino)propanoic acid hydrogen chloride
    • 14788-12-6
    • 3-(dimethylamino)propionic acid HCl salt
    • EN300-110453
    • GS-3831
    • 3-(dimethylamino)propanoic acid;hydrochloride
    • 3-(dimethyleamino) propionic acid hydrochloride
    • 3-Dimethylaminopropanoic acid HCl
    • SCHEMBL445971
    • 3-(Dimethylamino)propionic Acid Hydrochloride; 3-(N,N-Dimethylamino)propionic Acid Hydrochloride; 3-Dimethylaminopropanoic Acid HydrochlorideN,N-Dimethyl-beta-alanine Hydrochloride; beta-(Dimethylamino)propionic Acid Hydrochloride
    • MDL: MFCD02093464
    • Inchi: 1S/C5H11NO2.ClH/c1-6(2)4-3-5(7)8;/h3-4H2,1-2H3,(H,7,8);1H
    • InChI Key: JTNKXYWGZCNBCH-UHFFFAOYSA-N
    • SMILES: Cl.OC(CCN(C)C)=O

Computed Properties

  • Exact Mass: 153.05600
  • Monoisotopic Mass: 153.0556563g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 3
  • Complexity: 80.5
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 40.5
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: nothing

Experimental Properties

  • Color/Form: Not determined
  • Melting Point: 186.0 to 192.0 deg-C
  • Boiling Point: 192.6°C at 760 mmHg
  • Flash Point: 70.3°C
  • Water Partition Coefficient: almost transparency
  • PSA: 40.54000
  • LogP: 0.82470
  • Solubility: Not determined
  • Sensitiveness: Sensitive to air and humidity

3-(Dimethylamino)propanoic acid hydrochloride Security Information

3-(Dimethylamino)propanoic acid hydrochloride Customs Data

  • HS CODE:2922499990
  • Customs Data:

    China Customs Code:

    2922499990

    Overview:

    2922499990 Other amino acids and their esters and their salts(Except those containing more than one oxygen-containing group). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods) MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, The color of ethanolamine and its salt should be reported, The package of ethanolamine and its salt shall be declared

    Regulatory conditions:

    A.Customs clearance form for Inbound Goods
    B.Customs clearance form for outbound goods

    Inspection and quarantine category:

    P.Imported animals and plants\Quarantine of animal and plant products
    Q.Outbound animals and plants\Quarantine of animal and plant products
    R.Sanitary supervision and inspection of imported food
    S.Sanitary supervision and inspection of exported food
    M.Import commodity inspection
    N.Export commodity inspection

    Summary:

    HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

3-(Dimethylamino)propanoic acid hydrochloride Pricemore >>

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3-(Dimethylamino)propanoic acid hydrochloride Production Method

3-(Dimethylamino)propanoic acid hydrochloride Related Literature

Additional information on 3-(Dimethylamino)propanoic acid hydrochloride

3-(Dimethylamino)propanoic acid hydrochloride (CAS 14788-12-6): Properties, Applications, and Market Insights

3-(Dimethylamino)propanoic acid hydrochloride (CAS 14788-12-6) is an important organic compound with a wide range of applications in pharmaceuticals, chemical synthesis, and research. This white crystalline powder is known for its unique chemical properties, making it a valuable intermediate in various industrial processes. In this article, we will explore its molecular structure, key characteristics, applications, and current market trends.

The chemical formula of 3-(Dimethylamino)propanoic acid HCl is C5H12ClNO2, with a molecular weight of 153.61 g/mol. It features a carboxyl group and a tertiary amine group, which contribute to its reactivity and solubility in polar solvents like water and ethanol. Researchers often utilize this compound in peptide synthesis, drug development, and as a building block for more complex molecules.

One of the most common applications of 3-(Dimethylamino)propanoic acid hydrochloride salt is in the pharmaceutical industry, where it serves as a key intermediate for the synthesis of various active pharmaceutical ingredients (APIs). Its structural properties make it particularly useful in creating compounds with potential biological activity, including some that are being studied for their therapeutic effects.

Recent trends in chemical research have shown increased interest in 3-(Dimethylamino)propanoic acid HCl as a precursor for novel materials. With the growing demand for specialized chemicals in material science, this compound has found new applications in polymer modification and surface treatment technologies. Researchers are exploring its potential in creating smart materials with responsive properties.

The synthesis of 3-(Dimethylamino)propanoic acid hydrochloride typically involves the reaction of 3-(dimethylamino)propanoic acid with hydrochloric acid. This process yields a stable, crystalline product that is easier to handle and store than its free base counterpart. The hydrochloride salt form offers improved solubility characteristics, which is particularly valuable in many industrial applications.

Quality control is crucial when working with CAS 14788-12-6. Reputable suppliers typically provide certificates of analysis that include purity assessments (often ≥98%), moisture content, and residual solvent levels. These specifications are particularly important for pharmaceutical applications where stringent quality standards must be met.

From a safety perspective, 3-(Dimethylamino)propanoic acid HCl requires standard laboratory precautions. While not classified as highly hazardous, proper handling procedures should be followed, including the use of personal protective equipment and adequate ventilation. Material safety data sheets (MSDS) provide detailed information about handling, storage, and disposal requirements.

The global market for 3-(Dimethylamino)propanoic acid hydrochloride has shown steady growth in recent years, driven primarily by demand from the pharmaceutical sector. Asia-Pacific regions, particularly China and India, have emerged as significant producers and consumers of this chemical intermediate. Market analysts predict continued expansion as new applications are developed.

Storage recommendations for 3-(Dimethylamino)propanoic acid hydrochloride salt typically include keeping the material in a cool, dry place, protected from moisture and direct sunlight. Many suppliers offer the compound in various packaging options, from small laboratory quantities to bulk industrial-scale containers, depending on customer requirements.

Researchers frequently search for information about 3-(Dimethylamino)propanoic acid HCl solubility, synthesis methods, and potential applications. These search trends reflect the compound's growing importance in various scientific fields. Recent publications have explored its use in novel drug delivery systems and as a component in specialty coatings.

When comparing 3-(Dimethylamino)propanoic acid hydrochloride with similar compounds, its balanced properties of stability and reactivity make it particularly versatile. The hydrochloride salt form offers advantages in many synthetic processes compared to the free base, including better crystallinity and handling characteristics.

Future research directions for CAS 14788-12-6 may include exploring its potential in green chemistry applications. As industries seek more sustainable chemical processes, intermediates like this compound could play important roles in developing environmentally friendly synthetic routes for pharmaceuticals and specialty chemicals.

For laboratories and industrial users considering 3-(Dimethylamino)propanoic acid HCl, it's important to source the material from reputable suppliers who can provide consistent quality and technical support. Many suppliers now offer customized solutions, including specific purity grades or packaging options tailored to particular applications.

Analytical techniques commonly used to characterize 3-(Dimethylamino)propanoic acid hydrochloride include HPLC for purity assessment, NMR spectroscopy for structural confirmation, and various spectroscopic methods for quality control. These analytical methods ensure the compound meets the required specifications for its intended use.

The price of 3-(Dimethylamino)propanoic acid hydrochloride salt can vary depending on purity grade, quantity ordered, and market conditions. Recent market reports suggest stable pricing with moderate fluctuations, reflecting balanced supply and demand dynamics in the specialty chemicals sector.

In conclusion, 3-(Dimethylamino)propanoic acid hydrochloride (CAS 14788-12-6) represents an important chemical intermediate with diverse applications across multiple industries. Its unique combination of chemical properties, stability, and reactivity ensures its continued relevance in scientific research and industrial processes. As new applications emerge and synthesis methods evolve, this compound is likely to maintain its position as a valuable tool for chemists and researchers worldwide.

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