Cas no 14727-71-0 (4,5,9,10-Pyrenetetrone)
4,5,9,10-Pyrenetetrone Chemical and Physical Properties
Names and Identifiers
-
- 4,5,9,10-Pyrenetetrone
- pyrene-4,5,9,10-tetrone
- FQVOWPCGHLYSLB-UHFFFAOYSA-N
- SCHEMBL1445657
- 14727-71-0
- DTXSID40458809
- 4,5,9,10-TETRAHYDROPYRENE-4,5,9,10-TETRONE
- E76415
- YSWG406
- Pyrene-4,5,9,10-tetraone
- AKOS027325552
- CS-0111096
- BS-50805
- A898789
-
- MDL: MFCD11502676
- Inchi: 1S/C16H6O4/c17-13-7-3-1-4-8-11(7)12-9(15(13)19)5-2-6-10(12)16(20)14(8)18/h1-6H
- InChI Key: FQVOWPCGHLYSLB-UHFFFAOYSA-N
- SMILES: O=C1C(C2C=CC=C3C(C(C4=CC=CC1=C4C=23)=O)=O)=O
Computed Properties
- Exact Mass: 262.02658
- Monoisotopic Mass: 262.02660867g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 20
- Rotatable Bond Count: 0
- Complexity: 443
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 68.3
- XLogP3: 1.7
Experimental Properties
- Density: 1.604±0.06 g/cm3 (20 oC 760 Torr),
- Melting Point: >350 oC
- Solubility: Very slightly soluble (0.1 g/l) (25 o C),
- PSA: 68.28
4,5,9,10-Pyrenetetrone Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | P302921-1g |
4,5,9,10-Pyrenetetrone |
14727-71-0 | ≥98% | 1g |
¥2523.90 | 2023-09-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | P302921-250mg |
4,5,9,10-Pyrenetetrone |
14727-71-0 | ≥98% | 250mg |
¥1029.90 | 2023-09-01 | |
| Ambeed | A255507-100mg |
Pyrene-4,5,9,10-tetraone |
14727-71-0 | 98% | 100mg |
$18.0 | 2025-02-25 | |
| Ambeed | A255507-250mg |
Pyrene-4,5,9,10-tetraone |
14727-71-0 | 98% | 250mg |
$31.0 | 2025-02-25 | |
| Ambeed | A255507-1g |
Pyrene-4,5,9,10-tetraone |
14727-71-0 | 98% | 1g |
$93.0 | 2025-02-25 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | P29960-250mg |
4,5,9,10-Pyrenetetrone |
14727-71-0 | 250mg |
¥646.0 | 2021-09-08 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | P29960-1g |
4,5,9,10-Pyrenetetrone |
14727-71-0 | 1g |
¥1746.0 | 2021-09-08 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | P29960-100mg |
4,5,9,10-Pyrenetetrone |
14727-71-0 | 100mg |
¥436.0 | 2021-09-08 | ||
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-FG429-50mg |
4,5,9,10-Pyrenetetrone |
14727-71-0 | 98% | 50mg |
298.0CNY | 2021-07-10 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-FG429-200mg |
4,5,9,10-Pyrenetetrone |
14727-71-0 | 98% | 200mg |
804.0CNY | 2021-07-10 |
4,5,9,10-Pyrenetetrone Suppliers
4,5,9,10-Pyrenetetrone Related Literature
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Yaqing Liu,Jiangtao Ren,Jing Li,Jiyang Liu,Erkang Wang Chem. Commun., 2012,48, 802-804
-
Jialiang Yuan,Ran Dong,Yuan Li,Yang Liu,Zhuo Zheng,Yuxia Liu,Yan Sun,Benhe Zhong,Zhenguo Wu,Xiaodong Guo Chem. Commun., 2021,57, 13004-13007
-
Sandip Gangadhar Balwe,Yeon Tae Jeong Org. Biomol. Chem., 2018,16, 1287-1296
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Cheng Fang,Jinjian Wu,Zahra Sobhani,Md. Al Amin,Youhong Tang Anal. Methods, 2019,11, 163-170
Additional information on 4,5,9,10-Pyrenetetrone
Introduction to 4,5,9,10-Pyrenetetrone (CAS No. 14727-71-0)
4,5,9,10-Pyrenetetrone, identified by the Chemical Abstracts Service Number (CAS No.) 14727-71-0, is a polycyclic aromatic hydrocarbon derivative that has garnered significant attention in the field of chemobiology and pharmaceutical research. This compound, characterized by its tetrone structure embedded within a pyrene framework, exhibits unique chemical and biological properties that make it a subject of intense study. The molecular architecture of 4,5,9,10-Pyrenetetrone lends itself to various applications, particularly in the development of novel therapeutic agents and biochemical probes.
The structural uniqueness of 4,5,9,10-Pyrenetetrone arises from its fused ring system and the presence of four carbonyl groups at specific positions. This arrangement confers upon the molecule a high degree of reactivity and specificity, which are critical factors in drug design. Recent advancements in computational chemistry have enabled researchers to predict the binding affinities and interactions of 4,5,9,10-Pyrenetetrone with biological targets with unprecedented accuracy. These studies suggest that the compound may interact with proteins involved in cell signaling pathways, making it a potential candidate for modulating these pathways.
In the realm of medicinal chemistry, 4,5,9,10-Pyrenetetrone has been explored as a scaffold for designing molecules with antimicrobial and anti-inflammatory properties. Preliminary in vitro studies have demonstrated that derivatives of this compound exhibit promising activity against certain resistant bacterial strains. The mechanism by which 4,5,9,10-Pyrenetetrone exerts its effects appears to involve interference with bacterial cell wall synthesis and membrane integrity. This finding is particularly relevant in the context of rising concerns about antibiotic resistance worldwide.
Moreover, the photophysical properties of 4,5,9,10-Pyrenetetrone have been investigated for potential applications in bioimaging and photodynamic therapy. The compound’s ability to absorb and emit light at specific wavelengths makes it suitable for use as a fluorescent probe in cellular studies. Researchers have utilized 4,5,9,10-Pyrenetetrone to track intracellular processes and monitor the localization of target proteins in real time. Such applications hold promise for advancing our understanding of cellular dynamics and for developing new diagnostic tools.
The synthesis of 4,5,9,10-Pyrenetetrone presents a formidable challenge due to its complex structure. Traditional synthetic routes often involve multi-step reactions that require careful optimization to achieve high yields and purity. However recent innovations in synthetic methodologies have streamlined the process considerably. Transition metal-catalyzed reactions and photocatalytic approaches have emerged as powerful tools for constructing the pyrenetetrone core efficiently. These advancements not only facilitate access to 4,5,9,10-Pyrenetetrone but also enable the synthesis of its analogs with tailored properties.
The pharmacokinetic behavior of 4,5,9,10-Pyrenetetrone is another area of active investigation. Studies indicate that the compound exhibits moderate solubility in both aqueous and organic solvents which is advantageous for formulation purposes. Additionally preliminary toxicity assessments have shown that 4,5,9,10-pyrenetetrone is well-tolerated at subtherapeutic doses suggesting its potential for safe clinical use。 Further research is needed to fully characterize its metabolic pathways and excretion profiles。
In conclusion,4,5,9,10-pyrenetetrone(CAS No。14727-71-0)is a versatile compound with significant potential in pharmaceutical research。 Its unique structure,reactivity,and biological activity make it an attractive scaffold for drug discovery。Ongoing studies are aimed at elucidating its mechanisms of action,optimizing its synthesis,and exploring its therapeutic applications。As our understanding of this molecule grows,we can anticipate further breakthroughs that will contribute to the development of novel treatments for various diseases。
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