Cas no 146667-84-7 (Tert-butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate)
Tert-butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate is a versatile intermediate in organic synthesis, particularly in pharmaceutical and agrochemical applications. Its key structural features include a piperidine core with a Boc-protected amine and a 2-hydroxyethyl substituent, enhancing its utility in further functionalization. The Boc group provides stability under basic conditions while allowing selective deprotection under acidic conditions, facilitating controlled synthetic modifications. The hydroxyl group offers a reactive handle for derivatization, enabling coupling or oxidation reactions. This compound is valued for its compatibility with diverse reaction conditions and its role in constructing complex nitrogen-containing scaffolds. High purity and well-defined reactivity make it a reliable building block for medicinal chemistry and drug discovery.
146667-84-7 structure
Product Name:Tert-butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate
CAS No:146667-84-7
MF:C12H23NO3
MW:229.315923929214
MDL:MFCD04114970
CID:64979
PubChem ID:10421352
Update Time:2025-06-07
Tert-butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate Chemical and Physical Properties
Names and Identifiers
-
- tert-Butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate
- 3-(2-Hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester
- 1-Boc-piperidine-3-ethanol
- (3'S)-2-[1-(tert-butoxycarbonyl)piperidin-3-yl]ethanol
- 1-boc-3-(2-hydroxy-ethyl)-piperidine
- 1-boc-3-hydroxyethyl piperidine
- 1-N-Boc-piperidine-3-ethanol
- 1-Piperidinecarboxylicacid, 3-(2-hydroxyethyl)-, 1,1-dimethylethyl ester
- AG-D-91083
- N-BOC-3-PIPERIDINEETHANOL
- N-tert-butoxycarbonyl-3-(2-hydroxyethyl)piperidine
- PubChem11327
- tert-butyl 3-(2-hydroxyethyl)-1-piperidine
- N-Boc-3-(2-hydroxyethyl)piperidine
- 3-(2-HYDROXY-ETHYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- 1-PIPERIDINECARBOXYLIC ACID, 3-(2-HYDROXYETHYL)-, 1,1-DIMETHYLETHYL ESTER
- KSC525A4T
- SCHEMBL771181
- SY002824
- Tert-butyl3-(2-hydroxyethyl)piperidine-1-carboxylate
- A13559
- AB29458
- CS-W001853
- AKOS011659024
- DXABICKZWDHPIP-UHFFFAOYSA-N
- FT-0773265
- FT-0648139
- FT-0770422
- DTXSID40439633
- Z976797004
- DS-10754
- (R)-tert-Butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate; (R)-3-(2-Hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester
- tert-Butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate; 3-(2-Hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester
- 146667-84-7
- PB21853
- Q-102997
- (r)-1-n-boc-3-(2-hydroxyethyl)piperidine
- MFCD04114970
- AB29456
- CS-WAA0064
- A13561
- EN300-61996
- (S)-N-Boc-3-hyroxyethyl piperidine
- (S)-1-Boc-3-hyroxyethyl piperidine
- (R)-1-Boc-3-hyroxyethyl piperidine
- DB-011783
- DB-011747
- (R)-N-Boc-3-hyroxyethyl piperidine
- Tert-butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate
-
- MDL： MFCD04114970
- Inchi： 1S/C12H23NO3/c1-12(2,3)16-11(15)13-7-4-5-10(9-13)6-8-14/h10,14H,4-9H2,1-3H3
- InChI Key： DXABICKZWDHPIP-UHFFFAOYSA-N
- SMILES： O(C(C)(C)C)C(N1CCCC(CCO)C1)=O
Computed Properties
- Exact Mass: 229.16789
- Monoisotopic Mass: 229.16779360g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 16
- Rotatable Bond Count: 4
- Complexity: 235
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 1
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 49.8
- XLogP3: 1.5
Experimental Properties
- Color/Form: Colorless to Yellow Liquid
- Density: 1.0±0.1 g/cm3
- Melting Point: No data available
- Boiling Point: 324℃ at 760 mmHg
- Flash Point: 149.79℃
- Refractive Index: 1.479
- PSA: 49.77
- LogP: 1.95380
- Vapor Pressure: 0.0±1.6 mmHg at 25°C
Tert-butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate Security Information
- Signal Word：Warning
- Hazard Statement： H302;H315;H319;H335
- Warning Statement： P261;P280;P301+P312;P302+P352;P305+P351+P338
- Safety Instruction： H315 (100%) H319 (100%) H335 (100%)
- Storage Condition：Room temperature
Tert-butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-BA829-1g |
Tert-butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate |
146667-84-7 | 97% | 1g |
406.0CNY | 2021-07-12 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-BA829-250mg |
Tert-butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate |
146667-84-7 | 97% | 250mg |
225CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-BA829-5g |
Tert-butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate |
146667-84-7 | 97% | 5g |
1718.0CNY | 2021-07-12 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-BA829-100mg |
Tert-butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate |
146667-84-7 | 97% | 100mg |
100CNY | 2021-05-08 | |
| Fluorochem | 040769-1g |
1-N-Boc-Piperidine-3-ethanol |
146667-84-7 | 95% | 1g |
￡40.00 | 2022-03-01 | |
| Fluorochem | 040769-5g |
1-N-Boc-Piperidine-3-ethanol |
146667-84-7 | 95% | 5g |
￡157.00 | 2022-03-01 | |
| Fluorochem | 040769-10g |
1-N-Boc-Piperidine-3-ethanol |
146667-84-7 | 95% | 10g |
￡236.00 | 2022-03-01 | |
| Fluorochem | 040769-25g |
1-N-Boc-Piperidine-3-ethanol |
146667-84-7 | 95% | 25g |
￡567.00 | 2022-03-01 | |
| AstaTech | 56377-1/G |
1-N-BOC-PIPERIDINE-3-ETHANOL |
146667-84-7 | 98% | 1g |
$53 | 2023-09-17 | |
| AstaTech | 56377-5/G |
1-N-BOC-PIPERIDINE-3-ETHANOL |
146667-84-7 | 98% | 5g |
$198 | 2023-09-17 |
Tert-butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate Related Literature
-
Hyejin Moon,Aaron R. Wheeler,Robin L. Garrell,Chang-Jin “CJ” Kim Lab Chip, 2006,6, 1213-1219
-
Muniyandi Sankaralingam,So Hyun Jeon,Yong-Min Lee,Mi Sook Seo,Wonwoo Nam Dalton Trans., 2016,45, 376-383
-
Dhamodaran Manikandan,S. Amirthapandian,I. S. Zhidkov,A. I. Kukharenko,S. O. Cholakh,Ramaswamy Murugan Phys. Chem. Chem. Phys., 2018,20, 6500-6514
-
Alvin Tanudjaja,Shinsuke Inagi,Fusao Kitamura,Toshikazu Takata,Ikuyoshi Tomita Dalton Trans., 2021,50, 3037-3043
-
Chengbin Yang,Hing Lun Tsang,Pui Man Lau,Ken-Tye Yong,Ho Pui Ho,Siu Kai Kong Analyst, 2017,142, 3579-3587
146667-84-7 (Tert-butyl 3-(2-hydroxyethyl)piperidine-1-carboxylate) Related Products
- 163210-22-8(tert-Butyl 3-(3-hydroxypropyl)piperidine-1-carboxylate)
- 868067-71-4(1-Piperidinecarboxylic acid, 3-(4-hydroxybutyl)-, 1,1-dimethylethyl ester)
- 2167026-13-1(tert-butyl 3-(2-hydroxy-2-methylpropyl)piperidine-1-carboxylate)
- 863578-32-9(tert-butyl (3S)-3-(2-hydroxyethyl)piperidine-1-carboxylate)
- 2007921-25-5(TERT-BUTYL 9-HYDROXY-2-AZASPIRO[5.5]UNDECANE-2-CARBOXYLATE)
- 958026-99-8(tert-butyl 4-(2-hydroxyethyl)-3,3-dimethylpiperidine-1-carboxylate)
- 389889-62-7(tert-butyl (3R)-3-(2-hydroxyethyl)piperidine-1-carboxylate)
- 1341039-65-3(3-Boc-8-hydroxyethyl-3-azabicyclo[3.2.1]octane)
- 2306275-40-9(tert-Butyl 3-(2-hydroxyethyl)-4-methylpiperidine-1-carboxylate)
- 1824290-29-0(tert-butyl 4-(hydroxymethyl)-3-methylpiperidine-1-carboxylate)
Recommended suppliers
Henan Dongyan Pharmaceutical Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
Nanjing Jubai Biopharm
Gold Member
Audited Supplier
CN Supplier
Bulk
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
SHOCHEM(SHANGHAI) CO.,lTD
Gold Member
Audited Supplier
CN Supplier
Bulk
Enjia Trading Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
