Cas no 1463-67-8 (3,5-Dimethyl-1H-indole-2-carbaldehyde)

3,5-Dimethyl-1H-indole-2-carbaldehyde is a substituted indole derivative featuring a formyl group at the 2-position and methyl groups at the 3- and 5-positions. This compound serves as a versatile intermediate in organic synthesis, particularly in the preparation of heterocyclic compounds and pharmaceuticals. Its structural framework is valuable for constructing indole-based scaffolds, which are prevalent in bioactive molecules. The aldehyde functionality allows for further derivatization through condensation or nucleophilic addition reactions, while the methyl groups enhance steric and electronic properties. The product is characterized by high purity and stability, making it suitable for research and industrial applications requiring precise chemical modifications.
3,5-Dimethyl-1H-indole-2-carbaldehyde structure
1463-67-8 structure
Product Name:3,5-Dimethyl-1H-indole-2-carbaldehyde
CAS No:1463-67-8
MF:C11H11NO
MW:173.211142778397
MDL:MFCD07643177
CID:1076869
PubChem ID:6483893
Update Time:2025-06-14

3,5-Dimethyl-1H-indole-2-carbaldehyde Chemical and Physical Properties

Names and Identifiers

    • 3,5-Dimethyl-1H-indole-2-carbaldehyde
    • 3,5-dimethyl-1H-indole-2-carbaldehyde(SALTDATA: FREE)
    • 2-Formyl-3,5-dimethylindol
    • 3,5-Dimethylindol-2-carbaldehyd
    • 3,5-Dimethylindol-2-carboxaldehyd
    • 3,5-dimethylindole-2-carbaldehyde
    • BS-21422
    • MFCD07643177
    • 1H-Indole-2-carboxaldehyde, 3,5-dimethyl-
    • 1463-67-8
    • AKOS000303203
    • DTXSID90424352
    • 3,5-Dimethyl-1H-indole-2-carbaldehyde, AldrichCPR
    • CS-0208373
    • MDL: MFCD07643177
    • Inchi: 1S/C11H11NO/c1-7-3-4-10-9(5-7)8(2)11(6-13)12-10/h3-6,12H,1-2H3
    • InChI Key: XFYUNHFBHYCXIN-UHFFFAOYSA-N
    • SMILES: O=CC1=C(C)C2C=C(C)C=CC=2N1

Computed Properties

  • Exact Mass: 173.08400
  • Monoisotopic Mass: 173.084063974g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 1
  • Complexity: 204
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.6
  • Topological Polar Surface Area: 32.9?2

Experimental Properties

  • PSA: 32.86000
  • LogP: 2.59720

3,5-Dimethyl-1H-indole-2-carbaldehyde Security Information

  • Hazard Category Code: 36
  • Safety Instruction: 26
  • HazardClass:IRRITANT

3,5-Dimethyl-1H-indole-2-carbaldehyde Customs Data

  • HS CODE:2933990090
  • Customs Data:

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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3,5-Dimethyl-1H-indole-2-carbaldehyde Suppliers

Amadis Chemical Company Limited
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(CAS:1463-67-8)3,5-Dimethyl-1H-indole-2-carbaldehyde
Order Number:A1137500
Stock Status:in Stock
Quantity:5g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 22:44
Price ($):653.0

Additional information on 3,5-Dimethyl-1H-indole-2-carbaldehyde

Exploring the Properties and Applications of 3,5-Dimethyl-1H-indole-2-carbaldehyde (CAS No. 1463-67-8)

3,5-Dimethyl-1H-indole-2-carbaldehyde (CAS No. 1463-67-8) is a specialized organic compound that has garnered significant attention in the fields of medicinal chemistry, material science, and agrochemical research. This indole derivative, characterized by its aldehyde functional group and methyl substitutions at the 3rd and 5th positions, serves as a versatile building block for synthesizing more complex molecules. Its unique structural features make it a valuable intermediate in the development of pharmaceuticals, dyes, and functional materials.

One of the most frequently searched questions about 3,5-Dimethyl-1H-indole-2-carbaldehyde revolves around its synthetic applications. Researchers often inquire about its role in the preparation of heterocyclic compounds, which are pivotal in drug discovery. The compound's reactive aldehyde group allows for facile condensation reactions, enabling the formation of Schiff bases or other derivatives with potential biological activity. Recent studies highlight its utility in designing antimicrobial agents and anticancer scaffolds, aligning with the growing demand for novel therapeutics.

In the context of material science, 3,5-Dimethyl-1H-indole-2-carbaldehyde is explored for its photophysical properties. Its indole core contributes to fluorescence emission, making it a candidate for organic light-emitting diodes (OLEDs) or sensors. This aligns with the current trend of developing sustainable, organic-based electronic devices. Users searching for "indole-based fluorescent probes" or "OLED materials" will find this compound particularly relevant due to its tunable electronic characteristics.

Another hot topic tied to this compound is its green chemistry potential. With increasing emphasis on environmentally friendly synthesis, researchers are investigating catalytic methods to produce 3,5-Dimethyl-1H-indole-2-carbaldehyde with minimal waste. Questions like "How to synthesize indole aldehydes sustainably?" reflect this trend. Recent advancements in biocatalysis and microwave-assisted reactions have shown promise in optimizing its production while reducing energy consumption.

The compound's structural analogs are also a point of interest, particularly in structure-activity relationship (SAR) studies. For instance, modifying the methyl groups or the aldehyde moiety can significantly alter its biological or chemical properties. This flexibility makes it a favorite among chemists designing custom intermediates for targeted applications. Searches for "indole-2-carbaldehyde derivatives" often lead to discussions about this compound's adaptability.

From an industrial perspective, 3,5-Dimethyl-1H-indole-2-carbaldehyde is valued for its scalability. Manufacturers frequently seek information on "bulk suppliers of CAS 1463-67-8" or "high-purity indole aldehydes," underscoring its commercial viability. Quality control parameters, such as HPLC purity and melting point, are critical for buyers, ensuring consistency in downstream applications like pharmaceutical intermediates or specialty chemicals.

In summary, 3,5-Dimethyl-1H-indole-2-carbaldehyde (CAS No. 1463-67-8) stands at the intersection of innovation and practicality. Its multifaceted applications—from drug design to advanced materials—coupled with its alignment with sustainability goals, make it a compound of enduring relevance. As research continues to uncover new uses, its role in addressing contemporary scientific challenges will likely expand further.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:1463-67-8)3,5-Dimethyl-1H-indole-2-carbaldehyde
A1137500
Purity:99%
Quantity:5g
Price ($):653.0
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