Cas no 1461705-47-4 (2,3-Dichloro-5,6-diethylpyrazine)

2,3-Dichloro-5,6-diethylpyrazine is a halogenated pyrazine derivative characterized by its distinct molecular structure, featuring chlorine and ethyl substituents on the pyrazine ring. This compound is primarily utilized as a key intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and specialty chemicals. Its reactive dichloro groups enable selective functionalization, while the diethyl substituents influence steric and electronic properties, enhancing its utility in cross-coupling and heterocyclic transformations. The compound's stability under standard conditions and compatibility with various reaction conditions make it a versatile building block for researchers. Its precise structural attributes contribute to controlled reactivity, facilitating targeted synthesis of complex molecules.
2,3-Dichloro-5,6-diethylpyrazine structure
1461705-47-4 structure
Product Name:2,3-Dichloro-5,6-diethylpyrazine
CAS No:1461705-47-4
MF:C8H10Cl2N2
MW:205.084399700165
CID:2161268
PubChem ID:75480947
Update Time:2025-05-20

2,3-Dichloro-5,6-diethylpyrazine Chemical and Physical Properties

Names and Identifiers

    • 2,3-Dichloro-5,6-diethylpyrazine
    • 1461705-47-4
    • EN300-137648
    • F8880-2956
    • DB-239461
    • Z1688642811
    • AKOS026726688
    • Inchi: 1S/C8H10Cl2N2/c1-3-5-6(4-2)12-8(10)7(9)11-5/h3-4H2,1-2H3
    • InChI Key: IGPMBOSVPGVGPA-UHFFFAOYSA-N
    • SMILES: ClC1=C(N=C(CC)C(CC)=N1)Cl

Computed Properties

  • Exact Mass: 204.0221037g/mol
  • Monoisotopic Mass: 204.0221037g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 2
  • Complexity: 127
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 25.8
  • XLogP3: 3.4

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Additional information on 2,3-Dichloro-5,6-diethylpyrazine

Exploring the Versatile Applications and Properties of 2,3-Dichloro-5,6-diethylpyrazine (CAS No. 1461705-47-4)

2,3-Dichloro-5,6-diethylpyrazine (CAS No. 1461705-47-4) is a specialized heterocyclic compound that has garnered significant attention in recent years due to its unique structural features and broad applicability in various industries. As a chlorinated pyrazine derivative, this compound exhibits distinct chemical properties that make it valuable for research and industrial applications. The presence of both chlorine atoms and ethyl groups on the pyrazine ring creates a molecular structure that is particularly interesting for scientists working in material science and pharmaceutical development.

The growing interest in 2,3-Dichloro-5,6-diethylpyrazine can be attributed to several factors, including the increasing demand for novel organic intermediates in drug discovery and the expanding applications of heterocyclic compounds in advanced materials. Researchers are particularly intrigued by how the strategic placement of chlorine and ethyl groups on the pyrazine core influences the compound's reactivity and physical characteristics. These properties make it a promising candidate for various synthetic transformations and potential applications in multiple fields.

One of the most searched questions regarding 2,3-Dichloro-5,6-diethylpyrazine relates to its synthesis and purification methods. The compound is typically prepared through controlled chlorination of 5,6-diethylpyrazine, followed by careful purification processes to ensure high purity. Recent advancements in synthetic chemistry have led to more efficient production methods, making this compound more accessible for research purposes. The purity of 2,3-Dichloro-5,6-diethylpyrazine is crucial for its applications, especially in pharmaceutical research where impurity profiles can significantly impact biological activity.

In the pharmaceutical sector, 2,3-Dichloro-5,6-diethylpyrazine serves as a valuable building block for the development of new drug candidates. The pyrazine moiety is a common structural element in many biologically active compounds, and the specific substitution pattern in this derivative offers unique opportunities for medicinal chemistry. Researchers are exploring its potential in creating novel antimicrobial agents and other therapeutic compounds, particularly in light of the growing need for new antibiotics to combat drug-resistant pathogens.

The material science community has shown increasing interest in 2,3-Dichloro-5,6-diethylpyrazine due to its potential applications in organic electronics. The compound's ability to participate in various coupling reactions makes it attractive for creating conjugated systems that could be used in organic semiconductors or light-emitting materials. This aligns with current trends in sustainable technology development, where researchers are seeking more environmentally friendly alternatives to traditional inorganic materials.

Another frequently searched aspect of 2,3-Dichloro-5,6-diethylpyrazine concerns its physical and chemical properties. The compound typically appears as a white to off-white crystalline solid with moderate solubility in common organic solvents. Its melting point and stability profile make it suitable for various synthetic applications. The presence of two chlorine atoms on the pyrazine ring provides multiple sites for further functionalization, allowing chemists to create diverse derivatives for specific applications.

From a safety perspective, proper handling procedures for 2,3-Dichloro-5,6-diethylpyrazine are often searched by laboratory personnel. While not classified as highly hazardous, standard precautions for handling chlorinated organic compounds should be observed, including the use of appropriate personal protective equipment and proper ventilation. The compound's stability under normal storage conditions makes it relatively convenient to work with in research settings.

The market for 2,3-Dichloro-5,6-diethylpyrazine has seen steady growth in recent years, driven by increasing research activities in both academic and industrial settings. Suppliers typically offer the compound in various quantities, from small research samples to bulk quantities for industrial applications. Pricing trends reflect the specialized nature of this chemical, with costs varying based on purity levels and order volumes.

Looking to the future, research directions for 2,3-Dichloro-5,6-diethylpyrazine include exploring its potential in agrochemical applications and further investigating its utility in material science innovations. The compound's versatility as a synthetic intermediate continues to attract attention from multiple scientific disciplines, suggesting that its importance in chemical research will likely grow in the coming years.

For researchers considering working with 2,3-Dichloro-5,6-diethylpyrazine, it's important to consult recent literature to stay updated on the latest applications and synthetic methodologies. The compound's unique combination of substituents on the pyrazine scaffold offers numerous possibilities for creative molecular design, making it a valuable tool in modern chemical research and development.

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