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  José M. Rivera,Mariana Martín-Hidalgo,Jean C. Rivera-Ríos Org. Biomol. Chem., 2012,10, 7562-7565
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  Li-Hua Gan,Rui Wu,Jian-Lei Tian,Patrick W. Fowler Phys. Chem. Chem. Phys., 2017,19, 419-425
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• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Aldehyde/Ketone

1-(3,5-Dichlorophenyl)Ethan-1-One: A Comprehensive Overview

1-(3,5-Dichlorophenyl)ethan-1-one, also known by its CAS registry number 14401-72-0, is a chemical compound that has garnered significant attention in the fields of organic chemistry and pharmacology. This compound, often referred to as dichlorophenyl ketone, is characterized by its unique structure and diverse applications. In this article, we will delve into the properties, synthesis, applications, and recent research findings related to this compound.

The molecular structure of 1-(3,5-dichlorophenyl)ethan-1-one consists of a ketone group attached to a dichlorophenyl ring. The presence of two chlorine atoms at the 3 and 5 positions of the phenyl ring imparts distinct electronic and steric properties to the molecule. This structure not only influences its physical and chemical properties but also plays a crucial role in its reactivity and biological activity.

Recent studies have highlighted the potential of dichlorophenyl ketone in various areas of research. For instance, researchers have explored its role as a precursor in the synthesis of bioactive compounds. The compound's ability to undergo nucleophilic addition reactions has made it a valuable intermediate in organic synthesis. Additionally, its stability under certain reaction conditions has been leveraged in the development of novel pharmaceutical agents.

One of the most notable advancements involving CAS No. 14401-72-0 is its application in medicinal chemistry. Scientists have utilized this compound to design and synthesize potential drug candidates targeting various diseases. For example, derivatives of dichlorophenyl ketone have shown promise in inhibiting enzymes associated with neurodegenerative disorders such as Alzheimer's disease.

Furthermore, the environmental impact of dichlorophenyl ketone has been a subject of recent investigations. Researchers have assessed its biodegradability and toxicity levels under different environmental conditions. These studies are essential for understanding the compound's potential risks and ensuring its safe use in industrial and therapeutic applications.

In terms of synthesis, dichlorophenyl ketone can be prepared through several methods, including Friedel-Crafts acylation and nucleophilic aromatic substitution. The choice of synthesis route depends on factors such as reaction conditions, reagent availability, and desired product purity. Recent advancements in catalytic techniques have further optimized these processes, making them more efficient and cost-effective.

Another area where CAS No. 14401-72-0 has shown potential is in materials science. Its ability to form stable complexes with metal ions has led to its use in the development of novel coordination polymers and metal-organic frameworks (MOFs). These materials hold promise for applications in gas storage, catalysis, and sensing technologies.

In conclusion, dichlorophenyl ketone or CAS No. 14401-72-0 is a versatile compound with a wide range of applications across multiple disciplines. Its unique structure, reactivity, and biological activity continue to make it an area of active research interest. As new findings emerge, this compound is expected to play an even more significant role in advancing scientific knowledge and technological innovations.

• 90-98-2(4,4'-Dichlorobenzophenone)
• 92758-86-6(3,3',5,5'-Tetrachlorobenzophenone)
• 1341-24-8(Ethanone, 1-phenyl-,monochloro deriv. (9CI))
• 844884-95-3(3,3',5'-Trichlorobenzophenone)
• 844885-32-1((3,4-dichlorophenyl)(3,5-dichlorophenyl)methanone)
• 99-91-2(1-(4-chlorophenyl)ethan-1-one)
• 1016-78-0(3-Chlorobenzophenone)
• 99-02-5(3'-Chloroacetophenone)
• 7498-66-0((3-Chlorophenyl)(4-chlorophenyl)methanone)
• 284474-50-6(4'-Chloroacetophenone-2',3',5',6'-d4)