Cas no 1428532-93-7 (8-chloro-6-(trifluoromethyl)-1,2,4triazolo4,3-apyridin-3(2H)-one)

8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one is a heterocyclic compound featuring a fused triazolopyridine core with chloro and trifluoromethyl substituents. Its unique structure imparts significant reactivity and potential utility in pharmaceutical and agrochemical applications. The trifluoromethyl group enhances lipophilicity and metabolic stability, while the chloro substitution offers a handle for further functionalization. This compound serves as a versatile intermediate in the synthesis of biologically active molecules, particularly in the development of kinase inhibitors and antimicrobial agents. Its well-defined chemical properties and synthetic accessibility make it a valuable building block for medicinal chemistry research. Proper handling and storage under inert conditions are recommended due to its reactive functional groups.

8-chloro-6-(trifluoromethyl)-1,2,4triazolo4,3-apyridin-3(2H)-one structure

1428532-93-7 structure

Product Name:8-chloro-6-(trifluoromethyl)-1,2,4triazolo4,3-apyridin-3(2H)-one

CAS No:1428532-93-7

MF:C₇H₃ClF₃N₃O

MW:237.566430330276

MDL:MFCD12406875

CID:3163920

PubChem ID:74891415

Update Time:2025-10-28

8-chloro-6-(trifluoromethyl)-1,2,4triazolo4,3-apyridin-3(2H)-one Chemical and Physical Properties

Names and Identifiers

- 8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
- ZEWPPMJHVMHLHL-UHFFFAOYSA-N
- DTXSID901157859
- D79840
- 8-CHLORO-6-(TRIFLUOROMETHYL)-2H-[1,2,4]TRIAZOLO[4,3-A]PYRIDIN-3-ONE
- 1428532-93-7
- 8-chloro-6-(trifluoromethyl)-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one
- 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 8-chloro-6-(trifluoromethyl)-
- SCHEMBL19152183
- MFCD12406875
- AKOS027422314
- GS-1015
- 8-chloro-6-(trifluoromethyl)-1,2,4triazolo4,3-apyridin-3(2H)-one
- MDL： MFCD12406875
- Inchi： 1S/C7H3ClF3N3O/c8-4-1-3(7(9,10)11)2-14-5(4)12-13-6(14)15/h1-2H,(H,13,15)
- InChI Key： ZEWPPMJHVMHLHL-UHFFFAOYSA-N
- SMILES： ClC1=CC(C(F)(F)F)=CN2C(NN=C21)=O

Computed Properties

Exact Mass: 236.9916739g/mol
Monoisotopic Mass: 236.9916739g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 5
Heavy Atom Count: 15
Rotatable Bond Count: 0
Complexity: 424
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: 1.3
Topological Polar Surface Area: 44.7?2

8-chloro-6-(trifluoromethyl)-1,2,4triazolo4,3-apyridin-3(2H)-one Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
SHANG HAI XIAN DING Biotechnology Co., Ltd.	G14675-1g	8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one	1428532-93-7		1g	7456CNY	2021-05-08
SHANG HAI XIAN DING Biotechnology Co., Ltd.	G14675-250mg	8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one	1428532-93-7		250mg	2772CNY	2021-05-08
SHANG HAI XIAN DING Biotechnology Co., Ltd.	G14675-1g	8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one	1428532-93-7		1g	7456.0CNY	2021-07-13
SHANG HAI XIAN DING Biotechnology Co., Ltd.	G14675-250mg	8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one	1428532-93-7		250mg	2772.0CNY	2021-07-13
Apollo Scientific	PC53585-250mg	8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one	1428532-93-7		250mg	￡75.00	2025-02-21
abcr	AB445728-500 mg	8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one, min. 95%; .	1428532-93-7		500mg	€497.00	2023-04-22
abcr	AB445728-1 g	8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one, min. 95%; .	1428532-93-7		1g	€736.30	2023-04-22
Matrix Scientific	143372-1g	8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one, 95%	1428532-93-7	95%	1g	$487.00	2023-09-07
Frontier Specialty Chemicals	G14675-250 mg	8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one	1428532-93-7		250mg	$ 53.00	2022-11-04
Frontier Specialty Chemicals	G14675-1 g	8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one	1428532-93-7		1g	$ 126.00	2022-11-04