Cas no 14204-27-4 (N-(Phenylthio)phthalimide)

N-(Phenylthio)phthalimide is a sulfur-containing heterocyclic compound widely utilized as an intermediate in organic synthesis and pharmaceutical applications. Its key advantages include its role as a versatile building block for the preparation of thioether derivatives and its utility in radical reactions, particularly in polymer and material science. The compound’s stability under standard conditions and well-defined reactivity profile make it a reliable reagent for introducing the phenylthio moiety into target molecules. Additionally, its crystalline nature ensures ease of handling and purification. N-(Phenylthio)phthalimide is valued for its consistent performance in synthetic pathways, contributing to efficient and selective transformations.
N-(Phenylthio)phthalimide structure
N-(Phenylthio)phthalimide structure
Product Name:N-(Phenylthio)phthalimide
CAS No:14204-27-4
MF:C14H9NO2S
MW:255.291762113571
MDL:MFCD00192396
CID:120233
Update Time:2025-11-02

N-(Phenylthio)phthalimide Chemical and Physical Properties

Names and Identifiers

    • 1H-Isoindole-1,3(2H)-dione,2-(phenylthio)-
    • N-(PHENYLTHIO)PHTHALIMIDE
    • 2-phenylsulfanylisoindole-1,3-dione
    • 2-PHENYLSULFANYL-ISOINDOLE-1,3-DIONE
    • 2-(Phenylthio)isoindoline-1,3-dione
    • 2-(Phenylthio)-1,3-isoindolinedione
    • Oprea1_393002
    • Oprea1_026778
    • NMHKBABHRKQHOL-UHFFFAOYSA-N
    • 2-(Phenylthio)-1H-isoindole-1,3(2H)-dione
    • 1H-Isoindole-1,3(2H)-dione, 2-(phenylthio)-
    • 2-(Phenylsulfanyl)-1H
    • 2-(phenylsulfanyl)-2,3-dihydro-1H-isoindole-1,3-dione
    • 1H-Isoindole-1,3(2H)-dione, 2-(ph
    • N-(Phenylthio)phthalimide
    • MDL: MFCD00192396
    • Inchi: 1S/C14H9NO2S/c16-13-11-8-4-5-9-12(11)14(17)15(13)18-10-6-2-1-3-7-10/h1-9H
    • InChI Key: NMHKBABHRKQHOL-UHFFFAOYSA-N
    • SMILES: S(C1C=CC=CC=1)N1C(C2C=CC=CC=2C1=O)=O

Computed Properties

  • Exact Mass: 255.03500
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 18
  • Rotatable Bond Count: 2
  • Complexity: 328
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 2.5
  • Topological Polar Surface Area: 62.7

Experimental Properties

  • Color/Form: Not determined
  • Density: 1.42
  • Melting Point: 161.0 to 166.0 deg-C
  • Boiling Point: 432.2°C at 760 mmHg
  • Flash Point: 215.2°C
  • Refractive Index: 1.723
  • Solubility: DMSO: soluble25mg/mL, clear, yellow
  • PSA: 62.68000
  • LogP: 2.92780
  • Solubility: Not determined

N-(Phenylthio)phthalimide Security Information

  • WGK Germany:3
  • Safety Instruction: 24/25

N-(Phenylthio)phthalimide Customs Data

  • HS CODE:2930909090
  • Customs Data:

    China Customs Code:

    2930909090

    Overview:

    2930909090. Other organic sulfur compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Additional information on N-(Phenylthio)phthalimide

N-(Phenylthio)phthalimide (CAS No. 14204-27-4): Properties, Applications, and Market Insights

N-(Phenylthio)phthalimide (CAS No. 14204-27-4) is a specialized organic compound that has garnered significant attention in the chemical and pharmaceutical industries. This compound, also known as N-Phenylthiophthalimide, belongs to the class of phthalimide derivatives, which are widely recognized for their versatility in synthetic chemistry. The CAS number 14204-27-4 uniquely identifies this compound, ensuring precise identification in research and commercial applications.

The molecular structure of N-(Phenylthio)phthalimide features a phthalimide core linked to a phenylthio group, which imparts unique chemical properties. This combination makes it a valuable intermediate in the synthesis of more complex molecules. Researchers and manufacturers often seek N-(Phenylthio)phthalimide CAS 14204-27-4 for its role in producing agrochemicals, pharmaceuticals, and advanced materials. Its stability and reactivity under controlled conditions make it a preferred choice for various chemical transformations.

One of the most common applications of N-(Phenylthio)phthalimide is in the field of polymer chemistry. It serves as a key building block for creating high-performance polymers with enhanced thermal and mechanical properties. Additionally, its use in photoinitiators and crosslinking agents has been explored, particularly in the development of UV-curable coatings and adhesives. The demand for such materials has surged due to the growing emphasis on sustainable and eco-friendly technologies.

In the pharmaceutical sector, N-(Phenylthio)phthalimide 14204-27-4 is utilized as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its ability to participate in N-acylation reactions and other key transformations makes it indispensable in drug development. Recent studies have also highlighted its potential in anticancer drug research, where its derivatives exhibit promising biological activity. This has led to increased interest from biotech companies and academic researchers alike.

The market for N-(Phenylthio)phthalimide CAS No. 14204-27-4 is influenced by several factors, including advancements in green chemistry and the shift toward bio-based materials. As industries strive to reduce their environmental footprint, the demand for efficient and sustainable chemical intermediates like N-(Phenylthio)phthalimide is expected to rise. Furthermore, the compound's compatibility with flow chemistry and continuous manufacturing processes aligns with modern industrial trends.

From a regulatory perspective, N-(Phenylthio)phthalimide is generally regarded as safe for handling when proper precautions are followed. However, users are advised to consult safety data sheets (SDS) and adhere to good laboratory practices (GLP). The compound's stability under standard storage conditions ensures its longevity, making it a reliable choice for long-term projects.

In conclusion, N-(Phenylthio)phthalimide (CAS 14204-27-4) is a multifaceted compound with broad applications across multiple industries. Its unique chemical properties, coupled with its role in innovative research and industrial processes, underscore its importance in modern chemistry. As the demand for specialty chemicals continues to grow, N-(Phenylthio)phthalimide is poised to remain a critical component in the chemical landscape.

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