Catalytic enantioselective α-sulfenylation of β-ketocarbonyls by chiral primary amines?

Organic Chemistry Frontiers Pub Date: 2018-06-15 DOI: 10.1039/C8QO00496J

Abstract

A simple chiral primary amine catalyst was identified to enable effective catalysis in direct α-sulfenylation of acyclic and cyclic β-ketocarbonyls with good yields and excellent enantioselectivities.

Graphical abstract: Catalytic enantioselective α-sulfenylation of β-ketocarbonyls by chiral primary amines
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