Cas no 1400883-27-3 (2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one)
2,2,2-Trifluoro-1-(1H-indol-6-yl)ethan-1-one is a fluorinated indole derivative with significant utility in organic synthesis and pharmaceutical research. Its trifluoroacetyl group enhances electrophilic reactivity, making it a valuable intermediate for constructing complex heterocyclic frameworks. The indole moiety provides a versatile scaffold for further functionalization, enabling applications in medicinal chemistry, particularly in the development of bioactive molecules. The compound's high purity and stability ensure reliable performance in synthetic workflows. Its unique structural features, including electron-withdrawing effects from the trifluoromethyl group, contribute to selective reactivity in nucleophilic substitution and condensation reactions, making it a preferred choice for targeted molecular design.
1400883-27-3 structure
Product Name:2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one
CAS No:1400883-27-3
MF:C10H6F3NO
MW:213.15595293045
MDL:MFCD28678516
CID:4698557
PubChem ID:71504528
Update Time:2025-06-06
2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one Chemical and Physical Properties
Names and Identifiers
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- Ethanone, 2,2,2-trifluoro-1-(1H-indol-6-yl)-
- 2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one
-
- MDL: MFCD28678516
- Inchi: 1S/C10H6F3NO/c11-10(12,13)9(15)7-2-1-6-3-4-14-8(6)5-7/h1-5,14H
- InChI Key: ZXTSXCNZWOKBRW-UHFFFAOYSA-N
- SMILES: FC(C(C1C=CC2C=CNC=2C=1)=O)(F)F
Computed Properties
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 15
- Rotatable Bond Count: 1
- Complexity: 264
- XLogP3: 3.4
- Topological Polar Surface Area: 32.9
2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Enamine | EN300-1937090-0.05g |
2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one |
1400883-27-3 | 0.05g |
$732.0 | 2023-09-17 | ||
| Enamine | EN300-1937090-0.1g |
2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one |
1400883-27-3 | 0.1g |
$767.0 | 2023-09-17 | ||
| Enamine | EN300-1937090-0.25g |
2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one |
1400883-27-3 | 0.25g |
$801.0 | 2023-09-17 | ||
| Enamine | EN300-1937090-0.5g |
2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one |
1400883-27-3 | 0.5g |
$836.0 | 2023-09-17 | ||
| Enamine | EN300-1937090-1.0g |
2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one |
1400883-27-3 | 1g |
$871.0 | 2023-06-02 | ||
| Enamine | EN300-1937090-2.5g |
2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one |
1400883-27-3 | 2.5g |
$1707.0 | 2023-09-17 | ||
| Enamine | EN300-1937090-5.0g |
2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one |
1400883-27-3 | 5g |
$2525.0 | 2023-06-02 | ||
| Enamine | EN300-1937090-10.0g |
2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one |
1400883-27-3 | 10g |
$3746.0 | 2023-06-02 | ||
| Enamine | EN300-1937090-1g |
2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one |
1400883-27-3 | 1g |
$871.0 | 2023-09-17 | ||
| Enamine | EN300-1937090-5g |
2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one |
1400883-27-3 | 5g |
$2525.0 | 2023-09-17 |
2,2,2-trifluoro-1-(1H-indol-6-yl)ethan-1-one Related Literature
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Ni-Na Sun,Fengli Qu,Xiaobing Zhang,Shufang Zhang,Jinmao You Analyst, 2015,140, 1827-1831
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Mark D. Allendorf,Alauddin Ahmed,Tom Autrey,Jeffrey Camp,Eun Seon Cho,Maciej Haranczyk,Abhi Karkamkar,Di-Jia Liu,Katie R. Meihaus,Iffat H. Nayyar,Roman Nazarov,Donald J. Siegel,Vitalie Stavila,Jeffrey J. Urban,Srimukh Prasad Veccham,Brandon C. Wood Energy Environ. Sci., 2018,11, 2784-2812
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Mei-Yu Xu,Ya-Ting Wang,Qing-Ling Ni,Zi-Hao Zhang,Guang-Ming Liang,Liu-Cheng Gui Dalton Trans., 2016,45, 4993-4997
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Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099
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Eunice Y.-L. Hui,Bhimsen Rout,Yaw Sing Tan,Kok-Ping Chan,Charles W. Johannes Org. Biomol. Chem., 2018,16, 389-392
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