- Highly Regioselective Halogenation of Pyridine N-Oxide: Practical Access to 2-Halo-Substituted PyridinesChen, Ying; Huang, Jinkun; Hwang, Tsang-Lin; Chen, Maosheng J.; Tedrow, Jason S.; et al, Organic Letters, 2015, 17(12), 2948-2951
Cas no 138006-41-4 (3-Bromo-2,5-dichloropyridine)
3-Bromo-2,5-dichloropyridine is a halogenated pyridine derivative with the molecular formula C5H2BrCl2N. This heterocyclic compound features a pyridine ring substituted with bromine at the 3-position and chlorine atoms at the 2- and 5-positions, offering multiple reactive sites for further functionalization. Its high purity and stable structure make it valuable as a versatile intermediate in pharmaceutical synthesis and agrochemical applications. The presence of both bromine and chlorine substituents enhances its reactivity in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, enabling efficient construction of complex molecules. It is particularly useful in the development of active pharmaceutical ingredients (APIs) and specialty chemicals requiring precise halogen substitution patterns. The compound's well-defined crystalline form ensures consistent performance in synthetic applications.
3-Bromo-2,5-dichloropyridine structure
Product Name:3-Bromo-2,5-dichloropyridine
CAS No:138006-41-4
MF:C5H2BrCl2N
MW:226.886078357697
MDL:MFCD06659484
CID:64503
PubChem ID:12901596
Update Time:2025-07-02
3-Bromo-2,5-dichloropyridine Chemical and Physical Properties
Names and Identifiers
-
- 3-Bromo-2,5-dichloropyridine
- 2,5 DICHLORO-3-BROMO-PYRIDINE
- 2-Chloro-3-Bromo-5-Chloropyridine
- 2,5-Dichloro-3-Bromo Pyridine
- 2,5-dichloro-3-bromo-pyridine
- 3-bromo-2,5-dichloro-pyridine
- PYRIDINE, 3-BROMO-2,5-DICHLORO-
- 2,5-dichloro-3-bromopyridine
- Pyridine,3-bromo-2,5-dichloro-
- PubChem1173
- 3-bromo-2, 5-dichloropyridine
- 3-bromo-2.5-dichloro-pyridine
- Jsp002284
- CDBHWRZEXFQNBI-UHFFFAOYSA-N
- BCP22191
- 3-Bromo-2 pound not5-dichloropyridine
- 138006-41-4
- AB25941
- SY022285
- EN300-175311
- 3-Bromo-2,5-dichloropyridine, AldrichCPR
- B4832
- AS-14935
- FT-0654888
- AC-895
- SCHEMBL899507
- A2974
- MFCD06659484
- AKOS015851186
- AM20061724
- DTXSID20512574
- J-511833
- CS-W003322
- DB-023734
- 2,5Dichloro-3-BromoPyridine
-
- MDL： MFCD06659484
- Inchi： 1S/C5H2BrCl2N/c6-4-1-3(7)2-9-5(4)8/h1-2H
- InChI Key： CDBHWRZEXFQNBI-UHFFFAOYSA-N
- SMILES： BrC1C(=NC=C(C=1)Cl)Cl
Computed Properties
- Exact Mass: 224.87500
- Monoisotopic Mass: 224.87477g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 9
- Rotatable Bond Count: 0
- Complexity: 101
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: 3.2
- Topological Polar Surface Area: 12.9
Experimental Properties
- Color/Form: White or cream powder
- Density: 1,199g/cm
- Melting Point: 37.0 to 41.0 deg-C
- Boiling Point: 239℃ at 760 mmHg
- Flash Point: 98.3°C
- Refractive Index: 1,424-1,426
- PSA: 12.89000
- LogP: 3.15090
- Solubility: Insoluble in water
3-Bromo-2,5-dichloropyridine Security Information
-
Symbol:
- Prompt：warning
- Signal Word：Warning
- Hazard Statement： H315-H319
- Warning Statement： P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
- Hazardous Material transportation number：UN2811
- Hazard Category Code： 36/37/38-41-37/38-25
- Safety Instruction： S26
-
Hazardous Material Identification：
- HazardClass：6.1
- PackingGroup：III
- Storage Condition：0-10°C
- Safety Term：6.1
- Packing Group：III
- Risk Phrases：R36/37/38
3-Bromo-2,5-dichloropyridine Customs Data
- HS CODE：2933399090
- Customs Data：
China Customs Code:
2933399090Overview:
2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
3-Bromo-2,5-dichloropyridine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B4832-5g |
3-Bromo-2,5-dichloropyridine |
138006-41-4 | 98.0%(GC) | 5g |
3390.0CNY | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B4832-1g |
3-Bromo-2,5-dichloropyridine |
138006-41-4 | 98.0%(GC) | 1g |
735.0CNY | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B12983-5g |
3-Bromo-2,5-dichloropyridine |
138006-41-4 | 98% | 5g |
318.0CNY | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B12983-25g |
3-Bromo-2,5-dichloropyridine |
138006-41-4 | 98% | 25g |
1038.0CNY | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B12983-1g |
3-Bromo-2,5-dichloropyridine |
138006-41-4 | 98% | 1g |
110.0CNY | 2021-08-04 | |
| Matrix Scientific | 024606-25g |
3-Bromo-2,5-dichloropyridine, 98% |
138006-41-4 | 98% | 25g |
$315.00 | 2023-09-09 | |
| Matrix Scientific | 024606-5g |
3-Bromo-2,5-dichloropyridine, 98% |
138006-41-4 | 98% | 5g |
$138.00 | 2023-09-09 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-MI881-25g |
3-Bromo-2,5-dichloropyridine |
138006-41-4 | 95+% | 25g |
989CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-MI881-5g |
3-Bromo-2,5-dichloropyridine |
138006-41-4 | 95+% | 5g |
207.0CNY | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-MI881-1g |
3-Bromo-2,5-dichloropyridine |
138006-41-4 | 95+% | 1g |
69.0CNY | 2021-08-04 |
3-Bromo-2,5-dichloropyridine Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Triethylamine Solvents: Dichloromethane ; rt → -70 °C
1.2 Reagents: Oxalyl chloride ; -70 °C; 30 min, -70 °C
1.3 Reagents: Methanol
1.2 Reagents: Oxalyl chloride ; -70 °C; 30 min, -70 °C
1.3 Reagents: Methanol
Reference
3-Bromo-2,5-dichloropyridine Raw materials
3-Bromo-2,5-dichloropyridine Preparation Products
3-Bromo-2,5-dichloropyridine Suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:138006-41-4)3-Bromo-2,5-dichloropyridine
Order Number:LE106
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:37
Price ($):discuss personally
Email:[email protected]
3-Bromo-2,5-dichloropyridine Related Literature
-
Laure Théveau,Cédric Schneider,Olivier Querolle,Lieven Meerpoel,Vincent Levacher,Christophe Hoarau Org. Biomol. Chem. 2016 14 3459
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Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:138006-41-4)3-Bromo-2,5-dichloropyridine
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry