Cas no 138-39-6 (4-Aminomethylbenzenesulfonamide)
4-Aminomethylbenzenesulfonamide Chemical and Physical Properties
Names and Identifiers
-
- 4-Aminomethylbenzenesulfonamide
- alpha-aminotoluene-4-sulphonamide
- maphenide
- 4-(aminomethyl)Benzenesulfonamide
- Mafenide
- Maphenid
- Marprontil
- Mesudin
- Mesudrin
- NSC 34632
- Neofamid
- Paramenyl
- Septicid
- Sulfamylon
- p-(Aminomethyl)benzenesulfonamide
- p-Sulfamoylbenzylamine
- alpha-Amino-p-toluenesulfonamide
- Emilene
- Homonal
- Homosul
- Ambamide
- MAFENIDE [WHO-DD]
- Prestwick1_000166
- EN300-35248
- Mafenidum
- DB06795
- .alpha.-Amino-p-toluenesulfonamide
- Maphenidum
- KBio2_001365
- Mafenide [USAN:INN:BAN]
- MAFENIDE [INN]
- CAS-138-37-4
- NCGC00016403-03
- 4-sulfamoyl-benzyl-amine
- Oprea1_593766
- 4-Aminomethyl-benzenesulfonamide
- IDI1_000363
- KBio1_000363
- aromatic/heteroaromatic sulfonamide 5
- 6LH
- Mafenida (INN-Spanish)
- 4-(aminosulfonyl)benzylamine
- GS-4341
- 4-sulfamoylbenzylamine
- NINDS_000363
- Oprea1_661906
- C07106
- p-Toluenesulfonamide, .alpha.-amino-
- Spectrum4_000034
- BCP0726000212
- MAFENIDE [USAN]
- Homosulfamine (Salt/Mix)
- Mafenidum (INN-Latin)
- MAFENIDE [MART.]
- CHEBI:6633
- DTXSID6047860
- Marfanil (Salt/Mix)
- D06BA03
- NCGC00016403-01
- BSPBio_001943
- SDCCGMLS-0003097.P003
- BIDD:GT0346
- MAFENIDE [MI]
- Benzenesulfonamide, 4-(aminomethyl)-
- 58447S8P4L
- Spectrum2_000095
- 4-Homosufanilamide
- BPBio1_000035
- AB00053492
- 4-Homosulfanilamide
- SBI-0051431.P003
- Benzamsulfonamide
- NSC-34632
- Prestwick3_000166
- 4-(AMINOMETHYL)-1-BENZENESULFONAMIDE
- 4-(aminomethyl)benzene-1-sulfonamide
- Mafenide (USAN/INN)
- 138-39-6
- UNII-58447S8P4L
- DTXCID2027836
- KBioGR_000467
- KBioSS_001365
- SPBio_001952
- NS00007705
- BCP9000891
- BDBM10860
- p-Aminomethylbenzenesulfonamide
- BSPBio_000031
- MFCD00072084
- Homosulfaminum
- NSC34632
- aromatic sulfonamide compound 6
- Spectrum3_000482
- KBio3_001443
- NCGC00016403-04
- Mafenida
- AM20050422
- AB00053492_18
- Prestwick2_000166
- SPBio_000050
- Mafenidum [INN-Latin]
- p-Toluenesulfonamide, alpha-amino-
- Masudin (Salt/Mix)
- Prestwick0_000166
- NCGC00016403-11
- BCPP000172
- Homosulfanilamide
- EINECS 205-326-9
- KBio2_003933
- DivK1c_000363
- CHEMBL419
- 4-aminomethyl-benzenesulphonamide
- HY-B0614
- SCHEMBL41628
- A886248
- Malfamin
- NCGC00016403-02
- GTPL12697
- alpha-aminotoluene-4-sulphonamide; maphenide;Mafenide
- Mafenida [INN-Spanish]
- KBio2_006501
- TQ0026
- D02351
- Bensulfamide
- MAFENIDE (MART.)
- Q3843044
- Spectrum_000885
- AKOS001074998
- FT-0682668
- Spectrum5_000916
- MAFENIDE [VANDF]
- DB-002011
- BRD-K30649484-003-13-7
- BBL012326
- STK083032
- ALBB-014887
- benzylamine, 4-sulphamoyl-
- benzenesulfonamide, 4-(aminomethyl)-, acetate
-
- MDL： MFCD00072084
- Inchi： 1S/C7H10N2O2S/c8-5-6-1-3-7(4-2-6)12(9,10)11/h1-4H,5,8H2,(H2,9,10,11)
- InChI Key： TYMRLRRVMHJFTF-UHFFFAOYSA-N
- SMILES： S(C1C=CC(CN)=CC=1)(N)(=O)=O
Computed Properties
- Exact Mass: 186.04600
- Monoisotopic Mass: 186.046298
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 12
- Rotatable Bond Count: 2
- Complexity: 224
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: nothing
- Topological Polar Surface Area: 94.6
Experimental Properties
- Density: 1.345±0.06 g/cm3 (20 oC 760 Torr),
- Melting Point: 177-178 °C (decomposition)
- Boiling Point: 382°C at 760 mmHg
- Flash Point: 184.8°C
- Solubility: Slightly soluble (24 g/l) (25 o C),
- PSA: 94.56000
- LogP: 2.27410
- Solubility: Soluble in dilute acid and alkali
4-Aminomethylbenzenesulfonamide Security Information
- Hazard Statement： H302-H315-H319-H332-H335
- HazardClass：IRRITANT
- Storage Condition：Please store the product under the recommended conditions in the Certificate of Analysis.
4-Aminomethylbenzenesulfonamide Customs Data
- HS CODE：2935009090
- Customs Data：
China Customs Code:
2935009090Overview:
2935009090 Other sulphonates(Acyl)amine. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:35.0%
Declaration elements:
Product Name, component content, use to
Summary:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%
4-Aminomethylbenzenesulfonamide Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajce57298-1g |
Mafenide |
138-39-6 | 98% | 1g |
￥2607.00 | 2023-09-07 | |
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajce57298-50mg |
Mafenide |
138-39-6 | 98% | 50mg |
￥449.00 | 2023-09-07 | |
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajce57298-100mg |
Mafenide |
138-39-6 | 98% | 100mg |
￥629.00 | 2023-09-07 | |
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajce57298-200mg |
Mafenide |
138-39-6 | 98% | 200mg |
￥890.00 | 2023-09-07 | |
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajce57298-500mg |
Mafenide |
138-39-6 | 98% | 500mg |
￥1708.00 | 2023-09-07 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | A181384-5g |
4-Aminomethylbenzenesulfonamide |
138-39-6 | 96% | 5g |
￥2380.90 | 2023-09-04 | |
| TRC | A613490-100mg |
4-Aminomethylbenzenesulfonamide |
138-39-6 | 100mg |
$ 63.00 | 2023-09-08 | ||
| TRC | A613490-250mg |
4-Aminomethylbenzenesulfonamide |
138-39-6 | 250mg |
$ 81.00 | 2023-09-08 | ||
| TRC | A613490-500mg |
4-Aminomethylbenzenesulfonamide |
138-39-6 | 500mg |
$ 121.00 | 2023-09-08 | ||
| TRC | A613490-1g |
4-Aminomethylbenzenesulfonamide |
138-39-6 | 1g |
$ 135.00 | 2022-06-08 |
4-Aminomethylbenzenesulfonamide Suppliers
Audited Supplier
4-Aminomethylbenzenesulfonamide Related Literature
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Partha Sarathi Addy,Baisakhee Saha,N. D. Pradeep Singh,Amit K. Das,Jacob T. Bush,Clarisse Lejeune,Christopher J. Schofield,Amit Basak Chem. Commun. 2013 49 1930
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Utsab Manna,Rajdip Roy,Abhishek Dutta,Nabanita Roy Org. Biomol. Chem. 2023 21 2375
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Nabanita Roy,Hemanta Kumar Datta,Rajdip Roy,Parthasarathi Dastidar Chem. Commun. 2023 59 9400
-
Suode Cheng,Zhou Wei,Xiao Zhiming,Li Yang,Fan Xia Anal. Methods 2021 13 4452
-
A. H. Stead,R. Gill,T. Wright,J. P. Gibbs,A. C. Moffat Analyst 1982 107 1106
Additional information on 4-Aminomethylbenzenesulfonamide
Comprehensive Overview of 4-Aminomethylbenzenesulfonamide (CAS No. 138-39-6): Properties, Applications, and Industry Insights
4-Aminomethylbenzenesulfonamide (CAS No. 138-39-6), also known as 4-AMBS, is a sulfonamide derivative with significant relevance in pharmaceutical and chemical research. This compound features a benzene ring substituted with an aminomethyl group and a sulfonamide functional group, making it a versatile intermediate in organic synthesis. Its molecular formula, C7H10N2O2S, and structural properties have garnered attention for applications ranging from drug development to material science.
The growing interest in sulfonamide-based compounds stems from their broad biological activity, including antimicrobial and anti-inflammatory effects. Researchers frequently search for "4-Aminomethylbenzenesulfonamide uses" or "CAS 138-39-6 synthesis," reflecting its importance in medicinal chemistry. Recent studies highlight its potential as a building block for enzyme inhibitors and targeted therapies, aligning with trends in personalized medicine and sustainable drug design.
From a technical perspective, 4-AMBS exhibits moderate solubility in water and organic solvents, with a melting point of approximately 165–170°C. Its stability under controlled conditions makes it suitable for industrial-scale production. Analytical techniques like HPLC and NMR spectroscopy are commonly employed for purity verification, addressing frequent queries such as "how to analyze 4-Aminomethylbenzenesulfonamide."
Environmental and safety considerations are critical when handling 138-39-6. While not classified as hazardous, proper storage (e.g., in airtight containers at room temperature) is recommended. This aligns with the increasing focus on "green chemistry" and "safe chemical handling" in search trends, emphasizing the need for responsible usage in laboratories.
In the pharmaceutical sector, 4-Aminomethylbenzenesulfonamide serves as a precursor for diuretic agents and carbonic anhydrase inhibitors. Its structural motif is also explored in covalent organic frameworks (COFs) for advanced material applications. Industry reports suggest rising demand for high-purity grades (>98%), driven by R&D investments in bioconjugation technologies and prodrug development.
Future research directions may explore its role in antibiotic resistance solutions or nanocarrier systems—topics frequently appearing in scientific literature. As regulatory standards evolve, compliance with REACH and GMP guidelines remains essential for manufacturers, addressing common search terms like "4-AMBS supplier regulations."
For researchers seeking alternatives, structurally related compounds such as 4-sulfamoylbenzylamine may offer comparable functionality. This responsiveness to "4-Aminomethylbenzenesulfonamide substitutes" queries demonstrates the compound's interconnected role in chemical innovation networks.
138-39-6 (4-Aminomethylbenzenesulfonamide) Related Products
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- 918810-53-4(1,3-Benzenedisulfonamide, 5-(aminomethyl)-)
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- 21481-58-3(Benzenemethanaminium,4-(aminosulfonyl)-N,N,N-trimethyl-)
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- 628298-58-8(3-Sulfamoylbenzylamine)
