Cas no 1379324-57-8 (1-Azido-3-bromo-5-chlorobenzene)

1-Azido-3-bromo-5-chlorobenzene is a functionalized benzene derivative featuring azido, bromo, and chloro substituents at the 1, 3, and 5 positions, respectively. This compound serves as a versatile intermediate in organic synthesis, particularly in click chemistry applications due to the reactive azide group. The presence of both bromo and chloro groups enhances its utility in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, enabling further structural diversification. Its well-defined substitution pattern allows for regioselective modifications, making it valuable in pharmaceutical and materials science research. The compound is typically handled under controlled conditions due to the potential instability of the azide functionality.
1-Azido-3-bromo-5-chlorobenzene structure
1379324-57-8 structure
Product Name:1-Azido-3-bromo-5-chlorobenzene
CAS No:1379324-57-8
MF:C6H3BrClN3
MW:232.465118646622
CID:5784334
PubChem ID:129963952
Update Time:2025-11-02

1-Azido-3-bromo-5-chlorobenzene Chemical and Physical Properties

Names and Identifiers

    • 1379324-57-8
    • 1-azido-3-bromo-5-chlorobenzene
    • EN300-734530
    • 1-Azido-3-bromo-5-chlorobenzene
    • Inchi: 1S/C6H3BrClN3/c7-4-1-5(8)3-6(2-4)10-11-9/h1-3H
    • InChI Key: QZCMRZJLTMQCTN-UHFFFAOYSA-N
    • SMILES: BrC1=CC(=CC(=C1)N=[N+]=[N-])Cl

Computed Properties

  • Exact Mass: 230.91989g/mol
  • Monoisotopic Mass: 230.91989g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 181
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 4.2
  • Topological Polar Surface Area: 14.4?2

1-Azido-3-bromo-5-chlorobenzene Pricemore >>

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Additional information on 1-Azido-3-bromo-5-chlorobenzene

Comprehensive Overview of 1-Azido-3-bromo-5-chlorobenzene (CAS No. 1379324-57-8): Properties, Applications, and Market Insights

1-Azido-3-bromo-5-chlorobenzene (CAS No. 1379324-57-8) is a highly specialized aromatic compound that has gained significant attention in recent years due to its unique chemical properties and versatile applications. As a derivative of benzene, this compound features three distinct functional groups: an azido group, a bromo substituent, and a chloro substituent. These functional groups make it particularly valuable in organic synthesis, pharmaceutical research, and materials science.

The molecular structure of 1-Azido-3-bromo-5-chlorobenzene allows it to participate in various chemical reactions, including click chemistry and cross-coupling reactions. These reactions are essential in the development of new drugs, polymers, and advanced materials. Researchers often utilize this compound as a building block in the synthesis of more complex molecules, leveraging its reactive azido group for efficient conjugation with other chemical entities.

In the pharmaceutical industry, 1-Azido-3-bromo-5-chlorobenzene is frequently employed in the design of novel drug candidates. Its ability to undergo Huigsen cycloaddition reactions makes it a valuable tool for creating biologically active compounds. Recent studies have explored its potential in developing targeted therapies for diseases such as cancer and infectious diseases, aligning with the growing demand for precision medicine.

Beyond pharmaceuticals, this compound finds applications in material science and nanotechnology. Its incorporation into polymers and coatings can enhance material properties such as durability, conductivity, and thermal stability. With the rise of smart materials and green chemistry, researchers are increasingly interested in eco-friendly synthesis methods for compounds like 1-Azido-3-bromo-5-chlorobenzene.

The market for 1-Azido-3-bromo-5-chlorobenzene is expanding, driven by advancements in drug discovery and functional materials. Companies specializing in fine chemicals and custom synthesis are investing in scalable production methods to meet the growing demand. Additionally, the compound's role in bioconjugation techniques has made it a staple in diagnostic and therapeutic applications.

From a safety perspective, proper handling and storage of 1-Azido-3-bromo-5-chlorobenzene are crucial due to its reactive nature. Laboratories and industrial facilities must adhere to strict protocols to ensure safe usage. The compound's stability under various conditions is a subject of ongoing research, particularly in optimizing its performance in high-value applications.

In summary, 1-Azido-3-bromo-5-chlorobenzene (CAS No. 1379324-57-8) is a multifaceted compound with broad utility in modern chemistry. Its applications span pharmaceuticals, materials science, and nanotechnology, making it a critical component in cutting-edge research and industrial processes. As scientific innovation continues to evolve, the demand for this compound is expected to grow, further solidifying its importance in the chemical industry.

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