Cas no 137234-74-3 (4-Chloro-6-ethyl-5-fluoropyrimidine)
4-Chloro-6-ethyl-5-fluoropyrimidine is a fluorinated pyrimidine derivative with a chloro and ethyl substituent, offering versatile reactivity for pharmaceutical and agrochemical synthesis. Its halogenated structure facilitates nucleophilic substitution reactions, making it a valuable intermediate for constructing complex heterocyclic compounds. The presence of both chloro and fluoro groups enhances its utility in selective functionalization, while the ethyl group contributes to steric and electronic modulation. This compound is particularly useful in the development of active pharmaceutical ingredients (APIs) and specialty chemicals, where precise molecular tuning is critical. High purity and consistent quality ensure reliable performance in research and industrial applications.
137234-74-3 structure
Product Name:4-Chloro-6-ethyl-5-fluoropyrimidine
CAS No:137234-74-3
MF:C6H6ClFN2
MW:160.576643466949
MDL:MFCD07782087
CID:64467
PubChem ID:16743445
Update Time:2025-06-07
4-Chloro-6-ethyl-5-fluoropyrimidine Chemical and Physical Properties
Names and Identifiers
-
- 4-Chloro-6-ethyl-5-fluoropyrimidine
- 6-CHLORO-4-ETHYL-5-FLUORO-1,6-DIHYDROPYRIMIDINE
- 4-chloro-6-ethyl-5-flouropyrimidine
- 4-Chloro-2-methylsulfanyl-pyrimidine-5-carbonitrile
- 4-Chloro-6-ethyl-5-fluoro-pyrimidine
- Voriconazole Intermediate II
- PYRIMIDINE,4-CHLORO-6-ETHYL-5-FLUORO
- Pyrimidine,4-chloro-6-ethyl-5-fluoro-
- PYRIMIDINE, 4-CHLORO-6-ETHYL-5-FLUORO-
- PubChem7037
- KSC174S6P
- Jsp002244
- LKTGVRWVTAJGMS-UHFFFAOYSA-N
- BCP04247
- EBD51273
- CC0104
- LS20306
- CM14143
- RP22369
- PB10473
- TRA0013718
- N765
- SY011522
- HC210045
- BC650913
- AB0016025
- EN300-102307
- SCHEMBL372414
- 4-Chloro-6-ethyl-5-fluoropyrimidine, AldrichCPR
- MFCD07782087
- F0001-0470
- EC 604-010-1
- NS00004637
- AS-15052
- FT-0643264
- CS-B1291
- Z1198174780
- 4-chloro-6-ethyl-5-fluoro pyrimidine
- 137234-74-3
- DTXSID30587753
- AC-4747
- AKOS005063655
- Q-102789
- DB-042382
- DTXCID20538517
-
- MDL： MFCD07782087
- Inchi： 1S/C6H6ClFN2/c1-2-4-5(8)6(7)10-3-9-4/h3H,2H2,1H3
- InChI Key： LKTGVRWVTAJGMS-UHFFFAOYSA-N
- SMILES： ClC1=C(C(CC)=NC=N1)F
Computed Properties
- Exact Mass: 160.02000
- Monoisotopic Mass: 160.0203541g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 10
- Rotatable Bond Count: 1
- Complexity: 112
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 25.8
- XLogP3: 2.1
Experimental Properties
- Density: 1.286
- Boiling Point: 210.9°C at 760 mmHg
- Flash Point: 81oC
- Refractive Index: 1.4962
- PSA: 25.78000
- LogP: 1.83150
4-Chloro-6-ethyl-5-fluoropyrimidine Security Information
- Signal Word：Warning
- Hazard Statement： H302-H319
- Warning Statement： P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501
- Hazard Category Code： 20/21/22-36/37/38-41
- Safety Instruction： S22; S36/37/39; S45
- Safety Term：22-36/37/39-45
- Risk Phrases：R20/21/22
- HazardClass：8
- Storage Condition：Inert atmosphere,2-8°C
- PackingGroup：III
4-Chloro-6-ethyl-5-fluoropyrimidine Customs Data
- HS CODE：2933599090
- Customs Data：
China Customs Code:
2933599090Overview:
2933599090. Other compounds with pyrimidine ring in structure(Including other compounds with piperazine ring on the structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
4-Chloro-6-ethyl-5-fluoropyrimidine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | C366095-2.5g |
4-Chloro-6-ethyl-5-fluoropyrimidine |
137234-74-3 | 2.5g |
$ 213.00 | 2023-09-08 | ||
| TRC | C366095-25g |
4-Chloro-6-ethyl-5-fluoropyrimidine |
137234-74-3 | 25g |
$ 1673.00 | 2023-09-08 | ||
| Alichem | A039000034-100g |
4-Chloro-6-ethyl-5-fluoropyrimidine |
137234-74-3 | 98% | 100g |
169.57 USD | 2021-06-01 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 075571-100g |
4-Chloro-6-ethyl-5-fluoropyrimidine |
137234-74-3 | 95+% | 100g |
4193CNY | 2021-05-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 075571-25g |
4-Chloro-6-ethyl-5-fluoropyrimidine |
137234-74-3 | 95+% | 25g |
1542CNY | 2021-05-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 075571-5g |
4-Chloro-6-ethyl-5-fluoropyrimidine |
137234-74-3 | 95+% | 5g |
519CNY | 2021-05-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-GC564-25g |
4-Chloro-6-ethyl-5-fluoropyrimidine |
137234-74-3 | 98% | 25g |
312CNY | 2021-05-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-GC564-5g |
4-Chloro-6-ethyl-5-fluoropyrimidine |
137234-74-3 | 98% | 5g |
71.0CNY | 2021-07-13 | |
| Matrix Scientific | 075571-100g |
4-Chloro-6-ethyl-5-fluoropyrimidine, 95+% |
137234-74-3 | 95+% | 100g |
$258.00 | 2023-09-06 | |
| Matrix Scientific | 075571-25g |
4-Chloro-6-ethyl-5-fluoropyrimidine, 95+% |
137234-74-3 | 95+% | 25g |
$38.00 | 2023-09-06 |
4-Chloro-6-ethyl-5-fluoropyrimidine Suppliers
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:137234-74-3)4-Chloro-6-ethyl-5-fluoropyrimidine
Order Number:sfd10505;1685261
Stock Status:in Stock
Quantity:200kg/Company Customization
Purity:99.9%/98%
Pricing Information Last Updated:Friday, 19 July 2024 14:35
Price ($):discuss personally
Email:[email protected]
Tiancheng Chemical (Jiangsu) Co., Ltd
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Audited Supplier
(CAS:137234-74-3)4-氯-6-乙基-5-氟嘧啶
Order Number:LE1685261
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:32
Price ($):discuss personally
Email:[email protected]
NewCan Biotech Limited
Gold Member
Audited Supplier
(CAS:137234-74-3)4-Chloro-6-ethyl-5-fluoropyrimidine
Order Number:NC9399
Stock Status:
Quantity:10g
Purity:97%
Pricing Information Last Updated:Friday, 18 July 2025 16:15
Price ($):Price inquiry
Email:[email protected]
4-Chloro-6-ethyl-5-fluoropyrimidine Related Literature
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Joo Chuan Yeo,Kenry Lab Chip, 2016,16, 4082-4090
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A. B. F. da Silva,K. Capelle Phys. Chem. Chem. Phys., 2009,11, 4564-4569
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Matthew J. Gaunt,Jinquan Yu,Jonathan B. Spencer Chem. Commun., 2001, 1844-1845
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Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
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5. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
137234-74-3 (4-Chloro-6-ethyl-5-fluoropyrimidine) Related Products
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Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:137234-74-3)4-Chloro-6-ethyl-5-fluoropyrimidine
Purity:99.9%/98%
Quantity:200kg/Company Customization
Price ($):Inquiry/Inquiry
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:137234-74-3)4-氯-6-乙基-5-氟嘧啶
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry