Cas no 1350918-91-0 (N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyridin-2-amine)

N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine is a boronic ester derivative featuring a pyridine core functionalized with a benzylamine group. This compound is primarily utilized as a versatile intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the synthesis of complex biaryl structures. The presence of the pinacol boronate group ensures stability under ambient conditions while maintaining reactivity in palladium-catalyzed transformations. Its benzyl-substituted pyridine moiety enhances solubility in organic solvents, facilitating handling in synthetic applications. The product is particularly valuable in pharmaceutical and materials science research, where precise functionalization of heterocyclic frameworks is required. Care should be taken to store it under inert conditions to preserve boronate integrity.
N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyridin-2-amine structure
1350918-91-0 structure
Product Name:N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyridin-2-amine
CAS No:1350918-91-0
MF:C18H23BN2O2
MW:310.198424577713
MDL:MFCD11878175
CID:2110092
Update Time:2025-06-13

N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyridin-2-amine Chemical and Physical Properties

Names and Identifiers

    • N-benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine
    • 2-(BENZYLAMINO)PYRIDINE-4-BORONIC ACID PINACOL ESTER
    • MB10769
    • BENZYL-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDIN-2-YL]-AMINE
    • N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyridin-2-amine
    • MDL: MFCD11878175
    • Inchi: 1S/C18H23BN2O2/c1-17(2)18(3,4)23-19(22-17)15-10-11-20-16(12-15)21-13-14-8-6-5-7-9-14/h5-12H,13H2,1-4H3,(H,20,21)
    • InChI Key: UDLDINKNICOUBD-UHFFFAOYSA-N
    • SMILES: O1B(C2C=CN=C(C=2)NCC2C=CC=CC=2)OC(C)(C)C1(C)C

Computed Properties

  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 23
  • Rotatable Bond Count: 4
  • Complexity: 381
  • Topological Polar Surface Area: 43.4

N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyridin-2-amine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Ambeed
A1441858-1g
N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine
1350918-91-0 97%
1g
$731.0 2024-04-24
abcr
AB389489-1 g
2-(Benzylamino)pyridine-4-boronic acid pinacol ester; .
1350918-91-0
1g
€637.00 2023-04-25
abcr
AB389489-5g
2-(Benzylamino)pyridine-4-boronic acid pinacol ester; .
1350918-91-0
5g
€999.00 2025-04-21
abcr
AB389489-1g
2-(Benzylamino)pyridine-4-boronic acid pinacol ester; .
1350918-91-0
1g
€369.80 2025-04-21

Additional information on N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyridin-2-amine

Recent Advances in the Study of N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyridin-2-amine (CAS: 1350918-91-0)

N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyridin-2-amine (CAS: 1350918-91-0) is a boronic acid derivative that has garnered significant attention in the field of chemical biology and medicinal chemistry. This compound is particularly notable for its role as a key intermediate in the synthesis of various biologically active molecules, including kinase inhibitors and other therapeutic agents. Recent studies have explored its potential applications in drug discovery and development, with a focus on its unique chemical properties and reactivity.

One of the most promising aspects of this compound is its utility in Suzuki-Miyaura cross-coupling reactions, a widely used method for forming carbon-carbon bonds in organic synthesis. The presence of the boronic ester moiety in N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyridin-2-amine makes it an excellent candidate for such reactions, enabling the efficient construction of complex molecular architectures. Recent research has demonstrated its effectiveness in the synthesis of novel pyridine-based compounds, which are of interest for their potential pharmacological activities.

In addition to its synthetic applications, studies have also investigated the biological activity of N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyridin-2-amine and its derivatives. Preliminary findings suggest that these compounds may exhibit inhibitory effects on certain protein kinases, which are implicated in various diseases, including cancer and inflammatory disorders. Further mechanistic studies are underway to elucidate the precise molecular targets and pathways involved.

The stability and handling of N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyridin-2-amine have also been subjects of recent investigation. Researchers have developed optimized protocols for its storage and use, ensuring its reliability in both laboratory and industrial settings. These advancements are critical for scaling up production and facilitating its incorporation into larger drug discovery campaigns.

Looking ahead, the continued exploration of N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyridin-2-amine and related compounds holds great promise for the development of new therapeutic agents. Future research directions may include the design of more potent and selective derivatives, as well as the investigation of their pharmacokinetic and pharmacodynamic properties. Collaborative efforts between chemists, biologists, and pharmacologists will be essential to fully realize the potential of this versatile compound.

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