Benzylamines
Benzylamines are a class of organic compounds characterized by the presence of an amino group (-NH2) attached to a benzyl group (C6H5CH2-). These compounds are widely used in various applications due to their versatile nature and chemical reactivity. Structurally, they can be primary, secondary, or tertiary depending on the number of alkyl groups directly attached to the nitrogen atom.
Benzylamines find extensive use as intermediates in the synthesis of pharmaceuticals, agrochemicals, and dyes. Their ability to form hydrogen bonds and interact with biological systems makes them valuable in medicinal chemistry for targeting various receptors and enzymes. Additionally, they are employed as precursors for the preparation of other functionalized compounds through electrophilic aromatic substitution reactions or alkylation processes.
The properties of benzylamines vary based on their substituents and degree of functionalization, which influences their solubility, reactivity, and stability in different environments. Due to these characteristics, they are indispensable tools for organic chemists in the development of new materials and drugs.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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1,3,5-Tribenzylhexahydro-1,3,5-triazine | 2547-66-2 | C24H27N3 |
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2(1H)-Pyrimidinone,6-[(phenylmethyl)amino]- | 5785-16-0 | C11H11N3O |
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N-benzyl-4,5,6,7-tetrahydro-1,3-benzothiazol-2-amine | 15087-99-7 | C14H16N2S |
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N-benzyl-4-(4-bromophenyl)-1,3-thiazol-2-amine | 262372-91-8 | C16H13BrN2S |
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6-((4-chlorobenzyl)amino)pyrimidine-2,4(1H,3H)-dione | 21333-15-3 | C11H10ClN3O2 |
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4-(((1-Propyl-1H-pyrazol-3-yl)amino)methyl)phenol | 1006445-51-7 | C13H17N3O |
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N4-(4-Fluorobenzyl)pyrimidine-4,6-diamine | 1488042-66-5 | C11H11FN4 |
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N4-(4-Chlorobenzyl)pyrimidine-4,6-diamine | 1490661-46-5 | C11H11ClN4 |
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1-{4-benzyl-8-thia-4,6-diazatricyclo7.4.0.0^{2,7}trideca-1(9),2(7)-dien-6-yl}ethan-1-one | 57262-78-9 | C19H22N2OS |
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N-benzyl-2-chloro-5-(trifluoromethyl)pyrimidin-4-amine | 26243-43-6 | C12H9ClF3N3 |
Related Literature
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Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
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Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
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Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
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Ross Harder,David C. Dunand,Ian McNulty Nanoscale, 2017,9, 5686-5693
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Matthew J. Gaunt,Jinquan Yu,Jonathan B. Spencer Chem. Commun., 2001, 1844-1845
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