• 1. An atom-economical protocol for direct conversion of Baylis–Hillman alcohols to β-chloro aldehydes in water?
  Raktani Bikshapathi,Sai Prathima Parvathaneni,Vaidya Jayathirtha Rao Green Chem., 2017,19, 4446-4450
• 2. Aggregated-fluorescent detection of PFAS with a simple chip
  Cheng Fang,Jinjian Wu,Zahra Sobhani,Md. Al Amin,Youhong Tang Anal. Methods, 2019,11, 163-170
• 3. An artificial blood vessel implanted three-dimensional microsystem for modeling transvascular migration of tumor cells?
  Xue-Ying Wang,Ying Pei,Min Xie,Zi-He Jin,Ya-Shi Xiao,Yang Wang,Li-Na Zhang,Yan Li,Wei-Hua Huang Lab Chip, 2015,15, 1178-1187
• 4. Alternative donor substrates for inverting and retaining glycosyltransferases?
  Luke L. Lairson,Warren W. Wakarchuk Chem. Commun., 2007, 365-367
• 5. An aptasensor for detection of potassium ions based on RecJf exonuclease mediated signal amplification
  Bidou Wang,Xifeng Chen Analyst, 2014,139, 5695-5699

• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Prenol lipids Bicyclic monoterpenoids
• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Prenol lipids Monoterpenoids Bicyclic monoterpenoids

Comprehensive Guide to 1-Bromobicyclo[2.2.1]heptane (CAS No. 13474-70-9): Properties, Applications, and Industry Insights

1-Bromobicyclo[2.2.1]heptane (CAS No. 13474-70-9) is a specialized organic compound belonging to the class of bicyclic hydrocarbons with a bromine substituent. Its unique bridged ring structure and reactive bromine functional group make it a valuable intermediate in synthetic chemistry, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. This article explores its molecular characteristics, industrial relevance, and answers trending questions from researchers and chemists.

The compound’s systematic name, 1-bromobicyclo[2.2.1]heptane, reflects its norbornane skeleton (a bicyclic framework with two fused cyclohexane rings) and a bromine atom at the 1-position. Its CAS registry number, 13474-70-9, is critical for precise identification in chemical databases. Users often search for synonyms like "bromonorbornane" or "norbornyl bromide," highlighting its role in stereoselective synthesis and cross-coupling reactions.

Recent interest in sustainable chemistry has spurred discussions about 1-bromobicyclo[2.2.1]heptane as a precursor for green solvents and bio-based polymers. Researchers are investigating its potential in catalysis and carbon-carbon bond formation, aligning with the demand for eco-friendly synthetic routes. Questions like "How is 1-bromobicyclo[2.2.1]heptane used in asymmetric synthesis?" or "What are alternatives to halogenated intermediates?" dominate forums, reflecting industry shifts toward safer reagents.

From a technical perspective, 1-bromobicyclo[2.2.1]heptane exhibits notable steric hindrance due to its rigid structure, influencing its reactivity in nucleophilic substitution and radical reactions. Its boiling point, solubility, and stability under various conditions are frequently queried, underscoring the need for accurate physicochemical data in process design. Analytical techniques like NMR spectroscopy and GC-MS are essential for characterizing its purity, a topic often searched alongside "CAS 13474-70-9 analysis."

In the pharmaceutical industry, this compound serves as a building block for chiral auxiliaries and active pharmaceutical ingredients (APIs). Its application in peptide modification and ligand design is gaining traction, particularly in drug discovery programs targeting neurological disorders. Searches for "1-bromobicyclo[2.2.1]heptane in medicinal chemistry" reveal growing academic and commercial interest.

To optimize SEO visibility, this content integrates high-traffic keywords such as "brominated norbornane derivatives," "CAS 13474-70-9 suppliers," and "applications of bicyclic bromides." By addressing user intent—whether technical data, sourcing, or innovative uses—this guide enhances accessibility for chemists, procurement specialists, and R&D teams navigating the evolving landscape of fine chemicals.

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)