Cas no 134672-72-3 (2-(2,4-Difluorophenyl)ethanamine)
2-(2,4-Difluorophenyl)ethanamine is a fluorinated aromatic amine with the molecular formula C8H9F2N. This compound features a phenyl ring substituted with two fluorine atoms at the 2- and 4-positions, attached to an ethanamine side chain. Its structural properties make it a valuable intermediate in pharmaceutical and agrochemical synthesis, particularly in the development of active ingredients requiring fluorinated aromatic motifs. The difluorophenyl group enhances metabolic stability and lipophilicity, which can improve bioavailability in drug design. The primary amine functionality allows for further derivatization, enabling its use in amide formation, reductive amination, or as a building block for heterocyclic compounds. It is typically handled under inert conditions due to its amine reactivity.
134672-72-3 structure
Product Name:2-(2,4-Difluorophenyl)ethanamine
CAS No:134672-72-3
MF:C8H9F2N
MW:157.16056895256
MDL:MFCD01529878
CID:839331
Update Time:2025-06-09
2-(2,4-Difluorophenyl)ethanamine Chemical and Physical Properties
Names and Identifiers
-
- 2-(2,4-Difluorophenyl)ethanamine
- 2,4-Difluorophenethylamine
- Benzeneethanamine, 2,4-difluoro- (9CI)
- 2-(2,4-difluorophenyl)ethan-1-amine
- 2-(2,4-Difluorophenyl)ethylamine
- Benzeneethanamine, 2,4-difluoro-
- 2,4-difluorophenylethylamine
- OGCUAECIKFVXQG-UHFFFAOYSA-N
- 6230AA
- NE46762
- AM83273
- SY025989
- ST24027450
-
- MDL: MFCD01529878
- Inchi: 1S/C8H9F2N/c9-7-2-1-6(3-4-11)8(10)5-7/h1-2,5H,3-4,11H2
- InChI Key: OGCUAECIKFVXQG-UHFFFAOYSA-N
- SMILES: FC1C=C(C=CC=1CCN)F
Computed Properties
- Exact Mass: 157.07000
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 11
- Rotatable Bond Count: 2
- Complexity: 119
- Topological Polar Surface Area: 26
Experimental Properties
- Density: 1.169
- Boiling Point: 197 oC
- Flash Point: 87 oC
- PSA: 26.02000
- LogP: 2.16630
2-(2,4-Difluorophenyl)ethanamine Security Information
- Hazardous Material transportation number:2735
- HazardClass:8
- PackingGroup:Ⅲ
2-(2,4-Difluorophenyl)ethanamine Customs Data
- HS CODE:2921499090
- Customs Data:
China Customs Code:
2921499090Overview:
2921499090 Other aromatic monoamines and derivatives and their salts. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
2-(2,4-Difluorophenyl)ethanamine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | D839148-1g |
2-(2,4-Difluorophenyl)ethanamine |
134672-72-3 | 98% | 1g |
¥429.30 | 2022-01-10 | |
| Fluorochem | 075233-1g |
2-(2,4-Difluorophenyl)ethylamine |
134672-72-3 | 95% | 1g |
£67.00 | 2022-03-01 | |
| Fluorochem | 075233-5g |
2-(2,4-Difluorophenyl)ethylamine |
134672-72-3 | 95% | 5g |
£227.00 | 2022-03-01 | |
| Fluorochem | 075233-10g |
2-(2,4-Difluorophenyl)ethylamine |
134672-72-3 | 95% | 10g |
£430.00 | 2022-03-01 | |
| Fluorochem | 075233-25g |
2-(2,4-Difluorophenyl)ethylamine |
134672-72-3 | 95% | 25g |
£681.00 | 2022-03-01 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | D839148-250mg |
2-(2,4-Difluorophenyl)ethanamine |
134672-72-3 | 98% | 250mg |
¥167.40 | 2022-01-10 | |
| TRC | D475200-50mg |
2-(2,4-Difluorophenyl)ethanamine |
134672-72-3 | 50mg |
$ 50.00 | 2022-06-05 | ||
| TRC | D475200-100mg |
2-(2,4-Difluorophenyl)ethanamine |
134672-72-3 | 100mg |
$ 70.00 | 2022-06-05 | ||
| TRC | D475200-500mg |
2-(2,4-Difluorophenyl)ethanamine |
134672-72-3 | 500mg |
$ 275.00 | 2022-06-05 | ||
| Chemenu | CM117635-5g |
2-(2,4-Difluorophenyl)ethanamine |
134672-72-3 | 95+% | 5g |
$262 | 2021-06-17 |
2-(2,4-Difluorophenyl)ethanamine Related Literature
-
Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
-
Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
-
Manickam Bakthadoss,Tadiparthi Thirupathi Reddy,Vishal Agarwal,Duddu S. Sharada Chem. Commun., 2022,58, 1406-1409
-
Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
-
Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
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