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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Diazines Halopyrimidines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Diazines Pyrimidines and pyrimidine derivatives Halopyrimidines

Comprehensive Overview of (2,4-Dichloropyrimidin-5-yl)methanol (CAS No. 1346537-23-2)

(2,4-Dichloropyrimidin-5-yl)methanol (CAS No. 1346537-23-2) is a specialized pyrimidine derivative with significant applications in pharmaceutical and agrochemical research. This compound, characterized by its dichloropyrimidine core and hydroxymethyl functional group, has garnered attention for its role as a versatile building block in organic synthesis. Researchers and industry professionals frequently search for high-purity (2,4-Dichloropyrimidin-5-yl)methanol suppliers, synthetic routes, and its potential in drug discovery, reflecting its growing relevance in modern chemistry.

The structural uniqueness of 1346537-23-2 lies in its chlorinated pyrimidine scaffold, which is pivotal for designing small-molecule inhibitors and biologically active compounds. Recent trends in AI-driven drug design and computational chemistry have amplified interest in this molecule, as it serves as a key intermediate for kinase inhibitors and antiviral agents. Users often inquire about its solubility, stability, and reactivity under various conditions, highlighting the need for detailed technical data.

From a synthetic perspective, (2,4-Dichloropyrimidin-5-yl)methanol is synthesized via nucleophilic substitution or catalytic reduction of precursor compounds. Its methanol group offers a handle for further functionalization, making it invaluable for structure-activity relationship (SAR) studies. SEO analytics reveal frequent searches for scalable synthesis methods and green chemistry alternatives, aligning with the global push for sustainable chemical processes.

In pharmaceutical applications, this compound is explored for its potential in oncology and central nervous system (CNS) drug development. Its chlorine atoms enhance binding affinity to target proteins, a feature leveraged in fragment-based drug discovery. Queries like "CAS 1346537-23-2 price" or "buy (2,4-Dichloropyrimidin-5-yl)methanol" indicate commercial demand, while academic searches focus on its NMR spectra and HPLC purity analysis.

Environmental and regulatory considerations are also critical. Though not classified as hazardous, proper handling protocols for halogenated compounds are emphasized in safety guidelines. The compound’s biodegradability and ecotoxicology data remain areas of active investigation, addressing concerns raised by green chemistry advocates.

In summary, (2,4-Dichloropyrimidin-5-yl)methanol (CAS No. 1346537-23-2) bridges fundamental research and industrial innovation. Its dual utility in medicinal chemistry and material science, coupled with rising interest in custom synthesis and patent literature, ensures its prominence in scientific discourse. Future studies may explore its catalytic applications or polymeric derivatives, further expanding its interdisciplinary impact.

• 1780-36-5(2,4,6-Trichloro-5-methylpyrimidine)
• 37131-89-8(2,4-Dichloropyrimidine-5-carboxylic acid)
• 7627-39-6(2,4-DICHLORO-5-ETHOXYMETHYL-PYRIMIDINE)
• 89380-14-3(2,4-Dichloro-5-(methoxymethyl)pyrimidine)
• 1780-38-7(2,4,6-Trichloro-5-ethylpyrimidine)
• 1780-31-0(2,4-Dichloro-5-methylpyrimidine)
• 3177-24-0(2,4-Dichloropyrimidine-5-carbonitrile)
• 389799-45-5((4-Chloropyrimidin-5-yl)methanol)
• 54127-94-5(Pyrimidine, 2,4-dichloro-5-(2-methoxyethyl)-)
• 34171-40-9(2,4-Dichloro-5-ethylpyrimidine)