Cas no 1330750-35-0 (2-Ethoxy-3-propoxypyridine)

2-Ethoxy-3-propoxypyridine is a substituted pyridine derivative characterized by its ethoxy and propoxy functional groups at the 2- and 3-positions, respectively. This compound is primarily utilized as an intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its structural features enhance solubility and reactivity, making it valuable for cross-coupling reactions and heterocyclic modifications. The presence of alkoxy groups contributes to its stability and compatibility with various reaction conditions. It is typically handled under inert conditions due to its sensitivity to moisture and air. Suitable for research and industrial applications, this compound offers versatility in synthetic pathways requiring functionalized pyridine scaffolds.
2-Ethoxy-3-propoxypyridine structure
2-Ethoxy-3-propoxypyridine structure
Product Name:2-Ethoxy-3-propoxypyridine
CAS No:1330750-35-0
MF:C10H15NO2
MW:181.231602907181
CID:1024845
PubChem ID:54758820
Update Time:2025-08-05

2-Ethoxy-3-propoxypyridine Chemical and Physical Properties

Names and Identifiers

    • 2-Ethoxy-3-propoxypyridine
    • 2-ethoxy-3-propoxypyridine;
    • DTXSID10716549
    • CS-0208737
    • A888208
    • Pyridine, 2-ethoxy-3-propoxy-
    • BS-20891
    • SB53522
    • 1330750-35-0
    • MFCD19981543
    • AKOS015892221
    • MDL: MFCD19981543
    • Inchi: 1S/C10H15NO2/c1-3-8-13-9-6-5-7-11-10(9)12-4-2/h5-7H,3-4,8H2,1-2H3
    • InChI Key: PJAQCUKZLHHQBT-UHFFFAOYSA-N
    • SMILES: O(C1=CC=CN=C1OCC)CCC

Computed Properties

  • Exact Mass: 181.11000
  • Monoisotopic Mass: 181.110278721g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 5
  • Complexity: 130
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.4
  • Topological Polar Surface Area: 31.4?2

Experimental Properties

  • PSA: 31.35000
  • LogP: 2.26910

2-Ethoxy-3-propoxypyridine Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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2-Ethoxy-3-propoxypyridine Related Literature

Additional information on 2-Ethoxy-3-propoxypyridine

Professional Introduction to 2-Ethoxy-3-propoxypyridine (CAS No. 1330750-35-0)

2-Ethoxy-3-propoxypyridine, with the CAS number 1330750-35-0, is a specialized organic compound that has garnered significant attention in the field of pharmaceutical chemistry and medicinal research. This compound, featuring an ethoxy and propoxy substituent on a pyridine backbone, exhibits unique chemical properties that make it a valuable intermediate in the synthesis of various bioactive molecules.

The structural configuration of 2-Ethoxy-3-propoxypyridine imparts distinct reactivity and functionalization potential, making it a versatile building block in drug discovery and development. The presence of both ethoxy and propoxy groups allows for further chemical modifications, enabling the creation of complex molecular architectures. These modifications are crucial for tailoring the pharmacokinetic and pharmacodynamic profiles of potential therapeutic agents.

In recent years, there has been growing interest in exploring the applications of 2-Ethoxy-3-propoxypyridine in the synthesis of novel pharmaceuticals. Its pyridine core is a common motif in many bioactive compounds, including kinase inhibitors, antiviral agents, and anti-inflammatory drugs. The compound's ability to serve as a precursor for these molecules has made it a focal point in synthetic organic chemistry research.

One of the most compelling aspects of 2-Ethoxy-3-propoxypyridine is its role in the development of targeted therapies. Researchers have leveraged its structural features to design molecules that interact selectively with specific biological targets. For instance, derivatives of this compound have been investigated for their potential as inhibitors of enzymes involved in cancer progression. The ethoxy and propoxy groups provide handles for further functionalization, allowing chemists to optimize binding affinity and metabolic stability.

The synthesis of 2-Ethoxy-3-propoxypyridine typically involves multi-step organic reactions, often starting from readily available pyridine derivatives. Advanced synthetic methodologies, such as cross-coupling reactions and nucleophilic substitutions, are commonly employed to introduce the ethoxy and propoxy groups at the desired positions. These synthetic routes highlight the compound's importance as a key intermediate in industrial-scale pharmaceutical production.

In academic research, 2-Ethoxy-3-propoxypyridine has been used as a model compound to study reaction mechanisms and develop new synthetic strategies. Its unique reactivity profile has provided insights into how different functional groups influence chemical transformations. Such studies contribute to the broader understanding of organic chemistry principles and can lead to more efficient synthetic protocols.

The pharmacological potential of derivatives of 2-Ethoxy-3-propoxypyridine has also been explored in preclinical studies. These studies aim to evaluate the safety and efficacy of novel compounds derived from this scaffold. Preliminary results suggest that certain derivatives exhibit promising biological activity, making them attractive candidates for further development into therapeutic agents.

The industrial relevance of 2-Ethoxy-3-propoxypyridine extends beyond academic research. Pharmaceutical companies have recognized its value as a starting material for high-value intermediates. The ability to produce this compound efficiently and cost-effectively is crucial for scaling up production for commercial applications. Advances in process chemistry have enabled the optimization of synthetic routes, ensuring a reliable supply chain for researchers and manufacturers alike.

The future prospects for 2-Ethoxy-3-propoxypyridine are bright, with ongoing research efforts aimed at uncovering new applications and expanding its utility in drug discovery. Collaborative initiatives between academia and industry are likely to drive innovation, leading to the development of novel therapeutics based on this versatile compound.

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