• 1. One-step synthesis of a carbon dot-based fluorescent probe for colorimetric and ratiometric sensing of tetracycline
  Jing Xue,Na-Na Li,Dong-Mei Zhang,Cai-Feng Bi,Cun-Gang Xu,Ning-Ning Shi,Xia Zhang,Yu-Hua Fan Anal. Methods 2020 12 5097
• 2. Deep eutectic solvent-based liquid-phase microextraction for detection of plant growth regulators in edible vegetable oils
  Ting Tan,Zhan Li,Xuejin Mao,Yiqun Wan,Hongdeng Qiu Anal. Methods 2016 8 3511
• 3. Use of ammonium salts or binary mixtures derived from amino acids, glycine betaine, choline and indole-3-butyric acid as plant regulators
  Damian Krystian Kaczmarek,Anna Parus,Marek ?o?yński,Juliusz Pernak RSC Adv. 2020 10 43058
• 4. Simultaneous determination of 10 plant growth promoters in fruits and vegetables with a modified QuEChERS based liquid chromatography tandem mass spectrometry method
  Ren Shuiying,Gao Yun,Feng Shun,Lu Yi Anal. Methods 2015 7 9130
• 5. Synthesis, crystal structure, fluorescence and antimicrobial activity of a series of rare-earth complexes based on indolebutyric acid
  Zhi-Nan Wang,Xue-Ting Xu,Xiao Lv,Feng-Ying Bai,Shu-Qing Liu,Yong-Heng Xing RSC Adv. 2015 5 104263

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Indoles and derivatives 3-alkylindoles
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Indoles and derivatives Indoles 3-alkylindoles
• Pharmaceutical and Biochemical Products Pharmaceutical Active Ingredients Standard Substances
• Solvents and Organic Chemicals Organic Compounds Acids/Esters
• Pharmaceutical and Biochemical Products Pharmaceutical Intermediates
• Pesticide Chemicals

Comprehensive Overview of 4-(1H-indol-3-yl)butanoic acid (CAS No. 133-32-4): Properties, Applications, and Research Insights

4-(1H-indol-3-yl)butanoic acid (CAS No. 133-32-4), also known as indole-3-butyric acid (IBA), is a naturally occurring plant growth hormone belonging to the auxin family. This organic compound has garnered significant attention in both agricultural and pharmaceutical research due to its versatile biological activities. Structurally, it features an indole ring linked to a butanoic acid side chain, which is critical for its physiological functions. The compound is widely utilized in plant tissue culture, rooting agents, and as a precursor in the synthesis of other bioactive molecules.

In recent years, the demand for sustainable agriculture solutions has surged, driving interest in 4-(1H-indol-3-yl)butanoic acid as an eco-friendly alternative to synthetic growth regulators. Researchers are exploring its role in stress tolerance enhancement, particularly under drought conditions and soil salinity, which are pressing concerns in modern farming. Additionally, its potential in biostimulant formulations aligns with the global shift toward organic farming practices.

From a biochemical perspective, CAS No. 133-32-4 operates by stimulating cell elongation and division, primarily in root tissues. This mechanism has made it indispensable in horticulture for propagating cuttings and improving crop yields. Beyond agriculture, studies highlight its neuroprotective properties, with ongoing investigations into its applications in neurological disorders and anti-inflammatory therapies.

The synthesis of 4-(1H-indol-3-yl)butanoic acid typically involves Fischer indole synthesis or enzymatic conversion of tryptophan derivatives. Advances in green chemistry have further optimized its production, reducing reliance on hazardous reagents. Analytical techniques such as HPLC and mass spectrometry are employed to ensure purity, given its sensitivity to light degradation and oxidation.

Consumer trends indicate growing searches for "natural plant hormones" and "rooting hormone alternatives," reflecting broader interest in sustainable gardening. Frequently asked questions include "How does IBA compare to other auxins?" and "Can 4-(1H-indol-3-yl)butanoic acid improve indoor plant growth?"—topics addressed in recent peer-reviewed studies. Its compatibility with hydroponic systems also positions it as a key component in urban farming innovations.

In summary, 4-(1H-indol-3-yl)butanoic acid (CAS No. 133-32-4) exemplifies the intersection of agricultural science and biomedical research. Its multifaceted applications, coupled with rising environmental awareness, underscore its relevance in contemporary scientific discourse. Future research may unlock novel uses in biodegradable materials and precision agriculture, solidifying its status as a cornerstone compound in plant biotechnology.

• 830-96-6(3-Indolepropionic acid)
• 15142-91-3(3-(1H-Indol-3-yl)-2-methylpropanoic acid)
• 3569-20-8(3-(1H-indol-3-yl)butanoic Acid)
• 25177-65-5(6-(1H-indol-3-yl)hexanoic acid)
• 60096-23-3(Indole-3-butyric Acid Potassium Salt)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)