Cas no 1329793-61-4 (4-Chloro-3-methyl-2-pyridinemethanol 1-Oxide)

4-Chloro-3-methyl-2-pyridinemethanol 1-Oxide is a heterocyclic compound featuring a pyridine core substituted with chloro, methyl, and hydroxymethyl groups, along with an N-oxide moiety. This structure imparts unique reactivity, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. The presence of both electron-withdrawing (chloro) and electron-donating (hydroxymethyl) groups enhances its versatility in functionalization reactions, such as nucleophilic substitutions or oxidations. The N-oxide group further modifies electronic properties, facilitating regioselective transformations. Its stability under standard conditions ensures reliable handling in industrial and research applications. This compound is particularly useful in the development of bioactive molecules, owing to its balanced polarity and synthetic flexibility.
4-Chloro-3-methyl-2-pyridinemethanol 1-Oxide structure
1329793-61-4 structure
Product Name:4-Chloro-3-methyl-2-pyridinemethanol 1-Oxide
CAS No:1329793-61-4
MF:C7H8ClNO2
MW:173.596920967102
CID:2245937
Update Time:2025-06-12

4-Chloro-3-methyl-2-pyridinemethanol 1-Oxide Chemical and Physical Properties

Names and Identifiers

    • 4-Chloro-3-methyl-2-pyridinemethanol 1-Oxide
    • Inchi: 1S/C7H8ClNO2/c1-5-6(8)2-3-9(11)7(5)4-10/h2-3,10H,4H2,1H3
    • InChI Key: OITWZOHDMBRBHT-UHFFFAOYSA-N
    • SMILES: ClC1C=C[N+](=C(CO)C=1C)[O-]

Computed Properties

  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 134
  • Topological Polar Surface Area: 45.7

4-Chloro-3-methyl-2-pyridinemethanol 1-Oxide Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
C369505-10mg
4-Chloro-3-methyl-2-pyridinemethanol 1-Oxide
1329793-61-4
10mg
$ 190.00 2023-04-18
TRC
C369505-100mg
4-Chloro-3-methyl-2-pyridinemethanol 1-Oxide
1329793-61-4
100mg
$ 1487.00 2023-04-18

Additional information on 4-Chloro-3-methyl-2-pyridinemethanol 1-Oxide

Professional Introduction to 4-Chloro-3-methyl-2-pyridinemethanol 1-Oxide (CAS No. 1329793-61-4)

4-Chloro-3-methyl-2-pyridinemethanol 1-Oxide, with the CAS number 1329793-61-4, is a specialized organic compound that has garnered significant attention in the field of pharmaceutical chemistry and bioorganic synthesis. This compound, characterized by its unique structural and functional properties, serves as a crucial intermediate in the development of various pharmacologically active molecules. Its molecular structure, featuring a chlorinated pyridine ring and an hydroxymethyl group oxidized to an epoxide, makes it a versatile building block for medicinal chemists.

The< strong>pyridine core of this compound is a well-known scaffold in medicinal chemistry, widely recognized for its ability to interact with biological targets such as enzymes and receptors. The presence of a< strong>chloro substituent at the 4-position enhances its reactivity, making it an attractive candidate for further functionalization. Additionally, the< strong>methyl group at the 3-position and the< strong>hydroxymethyl group at the 2-position contribute to its complex reactivity profile, enabling diverse synthetic pathways.

In recent years, there has been a surge in research focusing on the development of novel heterocyclic compounds for therapeutic applications. The< strong>epoxide functionality in 4-Chloro-3-methyl-2-pyridinemethanol 1-Oxide is particularly noteworthy, as epoxides are known for their utility in constructing complex molecular architectures through ring-opening reactions. This property has been leveraged in the synthesis of various bioactive compounds, including those with potential antimicrobial and anti-inflammatory properties.

The pharmaceutical industry has shown considerable interest in< strong>pyridine derivatives, owing to their broad spectrum of biological activities. Studies have demonstrated that modifications within the pyridine ring can significantly alter the pharmacological properties of these compounds. For instance, the introduction of electron-withdrawing groups such as chloro can enhance binding affinity to biological targets, while electron-donating groups like methyl can influence metabolic stability.

Recent advancements in synthetic methodologies have enabled more efficient and scalable production of< strong>4-Chloro-3-methyl-2-pyridinemethanol 1-Oxide. These innovations have not only improved yield but also reduced costs, making it more accessible for industrial applications. The compound's stability under various reaction conditions has been a key factor in its adoption by synthetic chemists, allowing for seamless integration into multi-step synthetic routes.

The< strong>CAS number 1329793-61-4 provides a unique identifier for this compound, facilitating its recognition and use in scientific literature and regulatory filings. This standardized nomenclature ensures that researchers worldwide can accurately reference and utilize this compound in their studies. The growing body of literature on< strong>pyridine-based intermediates underscores its importance in drug discovery and development.

In conclusion, 4-Chloro-3-methyl-2-pyridinemethanol 1-Oxide is a multifaceted compound with significant potential in pharmaceutical research. Its unique structural features and reactivity make it an invaluable tool for medicinal chemists seeking to develop novel therapeutic agents. As research continues to uncover new applications for this compound, its importance in the field of chemical biology is expected to grow even further.

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