• 1. Assignment of the charge-transfer bands in some metal phthalocyanines. Evidence for the S= 1 state of iron (II) phthalocyanine in solution
  Martin J. Stillman,Andrew J. Thomson J. Chem. Soc. Faraday Trans. 2 1974 70 790
• 2. Organic synthesis with the most abundant transition metal–iron: from rust to multitasking catalysts
  Sujoy Rana,Jyoti Prasad Biswas,Sabarni Paul,Aniruddha Paik,Debabrata Maiti Chem. Soc. Rev. 2021 50 243
• 3. (μ-Peroxo)bis[pyridine(phthalocyaninato)iron(iii)] as a convenient catalyst for the four-electron reduction of dioxygen
  Kenichi Oyaizu,Agus Haryono,Junichiro Natori,Eishun Tsuchida J. Chem. Soc. Faraday Trans. 1998 94 3737
• 4. A soluble iron(ii)-phthalocyanine-catalyzed intramolecular C(sp3)–H amination with alkyl azides
  Tingjie You,Si-Hao Zeng,Jianqiang Fan,Liangliang Wu,Fangyuan Kang,Yungen Liu,Chi-Ming Che Chem. Commun. 2021 57 10711
• 5. Synthesis and properties of N-methylimidazole solvates of vanadium(ii), chromium(ii) and iron(ii) phthalocyanines. Strong NIR absorption in VII(MeIm)2(Pc2?)
  Dmitri V. Konarev,Alexey V. Kuzmin,Yoshiaki Nakano,Salavat S. Khasanov,Akihiro Otsuka,Hideki Yamochi,Hiroshi Kitagawa,Rimma N. Lyubovskaya Dalton Trans. 2018 47 4661

• Material Chemicals Electrical Materials Biosensor Materials
• Material Chemicals Colorants and Pigments Pigments
• Material Chemicals Electrical Materials

Iron(II) phthalocyanine (CAS No. 132-16-1): A Comprehensive Overview of Its Applications and Recent Research

Iron(II) phthalocyanine, with the chemical formula C₃₂H₁₆N₈Fe and CAS number 132-16-1, is a prominent macrocyclic compound belonging to the phthalocyanine family. This vibrant blue pigment has garnered significant attention in various scientific and industrial domains due to its unique structural and electronic properties. The compound's iron(II) center imparts exceptional stability, making it a valuable candidate for numerous applications, ranging from imaging agents in biomedicine to advanced materials in nanotechnology.

The structure of Iron(II) phthalocyanine consists of a macrocyclic framework composed of four isocyanine units, forming a porphyrin-like core. The presence of the iron(II) ion at the center enhances its magnetic and optical characteristics, which are pivotal for its diverse applications. This compound's ability to absorb light in the near-infrared region (NIR) has made it particularly useful in photodynamic therapy and fluorescence imaging.

In recent years, significant advancements have been made in leveraging Iron(II) phthalocyanine for biomedical applications. One of the most notable areas is its use as a contrast agent in magnetic resonance imaging (MRI). The paramagnetic properties of the iron(II) center allow for enhanced relaxation times, improving image contrast and resolution. This has led to extensive research into developing novel MRI contrast agents based on phthalocyanines for early detection and monitoring of diseases such as cancer.

Moreover, Iron(II) phthalocyanine has shown promise in photodynamic therapy (PDT), a treatment modality that utilizes light-activated compounds to induce cell death in target tissues. The compound's ability to generate reactive oxygen species upon irradiation with specific wavelengths of light makes it an effective photosensitizer. Recent studies have demonstrated its potential in treating various types of cancer, including gliomas and melanomas, by selectively destroying malignant cells while minimizing damage to healthy tissues.

The compound's stability and biocompatibility also make it an attractive candidate for drug delivery systems. Researchers have explored using Iron(II) phthalocyanine-based nanoparticles as carriers for therapeutic agents, enabling targeted delivery to specific sites within the body. This approach not only enhances the efficacy of treatments but also reduces side effects associated with conventional drug delivery methods.

In addition to its biomedical applications, Iron(II) phthalocyanine has found utility in the field of nanotechnology. Its unique electronic properties make it suitable for use in organic electronics, such as organic light-emitting diodes (OLEDs) and photovoltaic cells. The compound's ability to absorb a broad spectrum of light increases the efficiency of these devices, making them more viable for commercial applications.

The environmental impact of using Iron(II) phthalocyanine has also been a subject of interest. Studies have shown that this compound is highly resistant to degradation, which could pose challenges in terms of disposal and environmental persistence. However, research efforts are ongoing to develop sustainable methods for synthesizing and recycling phthalocyanines, ensuring their use is both effective and environmentally responsible.

The synthesis of Iron(II) phthalocyanine typically involves cyclization reactions that form the macrocyclic structure around the iron(II) ion. Advances in synthetic methodologies have enabled the production of high-purity forms of this compound, which is crucial for its intended applications. Techniques such as metallophthalocyanine synthesis have been refined to produce compounds with tailored properties, enhancing their suitability for specific uses.

The future prospects for Iron(II) phthalocyanine are vast and multifaceted. Ongoing research aims to expand its applications into areas such as catalysis, where its unique electronic properties could be harnessed for more efficient chemical transformations. Additionally, efforts are being made to improve its biodegradability and reduce potential environmental risks associated with its use.

In conclusion, Iron(II) phthalocyanine, with its CAS number 132-16-1, represents a cornerstone material in modern science and technology. Its versatility spans from life-saving medical applications to cutting-edge technological innovations. As research continues to uncover new possibilities for this remarkable compound, its impact on society is poised to grow even further.

• 14285-56-4(Iron,chloro[29H,31H-phthalocyaninato(2-)-kN29,kN30,kN31,kN32]-, (SP-5-12)-)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)