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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acid esters
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Benzoic acid esters

Comprehensive Overview of 5-Bromo-2,4-dichloro-benzoic acid methyl ester (CAS No. 1305712-91-7)

5-Bromo-2,4-dichloro-benzoic acid methyl ester is a specialized organic compound widely utilized in pharmaceutical and agrochemical research. With the CAS registry number 1305712-91-7, this ester derivative has garnered significant attention due to its versatile applications in synthetic chemistry. The compound's molecular structure, featuring a bromine and two chlorine substituents on a benzoic acid backbone, makes it a valuable intermediate for designing bioactive molecules. Researchers often explore its reactivity in cross-coupling reactions and esterification processes, aligning with current trends in sustainable chemistry and green synthesis.

In recent years, the demand for halogenated aromatic esters like 5-Bromo-2,4-dichloro-benzoic acid methyl ester has surged, driven by their role in developing API intermediates (Active Pharmaceutical Ingredients). This compound's unique electrophilic properties enable precise modifications, addressing key challenges in drug discovery, such as selective functionalization and structural diversification. Laboratories frequently search for high-purity CAS 1305712-91-7 suppliers, reflecting its criticality in small-molecule synthesis workflows. Additionally, its stability under ambient conditions makes it a preferred choice for long-term storage in research settings.

The synthesis of 5-Bromo-2,4-dichloro-benzoic acid methyl ester typically involves esterification of the corresponding carboxylic acid with methanol, catalyzed by acids like sulfuric acid or via DCC coupling. Modern protocols emphasize solvent-free reactions or microwave-assisted synthesis to enhance yield and reduce environmental impact—a hotspot in contemporary organic chemistry. Analytical techniques such as HPLC, NMR, and mass spectrometry are employed to verify its purity, a topic frequently queried in academic forums and patent literature.

From an industrial perspective, CAS 1305712-91-7 is pivotal in producing crop protection agents and herbicide precursors, resonating with global discussions on food security and sustainable agriculture. Its bioisosteric potential (replacing hydrogen with halogens to modulate bioactivity) is another area of exploration, often highlighted in medicinal chemistry webinars. Users also frequently inquire about its safety data sheets (SDS) and handling precautions, underscoring the importance of laboratory safety compliance.

Innovations in catalytic methodologies have further expanded the utility of 5-Bromo-2,4-dichloro-benzoic acid methyl ester. For instance, palladium-catalyzed Buchwald-Hartwig amination or Sonogashira coupling reactions leverage its aryl halide moieties to construct complex heterocycles. Such applications align with trending searches on click chemistry and fragment-based drug design. Moreover, computational studies using DFT calculations predict its reactivity patterns, a niche yet growing interest among computational chemists.

To conclude, 5-Bromo-2,4-dichloro-benzoic acid methyl ester (CAS 1305712-91-7) exemplifies the intersection of traditional organic synthesis and cutting-edge research. Its multifaceted roles—from pharmaceutical intermediates to agrochemical building blocks—ensure its relevance in evolving scientific landscapes. As industries prioritize cost-effective scalability and eco-friendly protocols, this compound will likely remain a staple in high-value chemical manufacturing.

• 862243-37-6(BENZOIC ACID, 5-BROMO-2,4-DICHLORO-, ETHYL ESTER)
• 203573-12-0(Benzoic acid, 4-bromo-2,3,5,6-tetrachloro-, methyl ester)
• 933672-42-5(Methyl 2-chloro-3,5-dibromobenzoate)
• 76008-73-6(Ethyl 5-bromo-2-chlorobenzoate)
• 251085-87-7(Methyl 5-bromo-2-chlorobenzoate)
• 951884-96-1(3-Bromo-2,4-dichlorobenzoic acid)
• 871224-19-0(Methyl 3-bromo-2-chlorobenzoate)
• 791137-20-7(5-Bromo-2,4-dichlorobenzoic acid)
• 1263377-05-4(Methyl 5-bromo-2-chloro-3-methylbenzoate)
• 80257-12-1(3-bromo-2,6-dichloro-benzoic acid)